Periventricular pseudocysts of noninfectious origin: Prenatal associated findings and prognostic factors.
Adult
Cysts
/ congenital
Female
Fetal Diseases
/ diagnosis
Humans
Infant, Newborn
Israel
/ epidemiology
Magnetic Resonance Imaging
Male
Nervous System Malformations
/ diagnosis
Pregnancy
Pregnancy Outcome
/ epidemiology
Prenatal Diagnosis
/ methods
Prognosis
Retrospective Studies
Risk Factors
Ultrasonography, Prenatal
Young Adult
Journal
Prenatal diagnosis
ISSN: 1097-0223
Titre abrégé: Prenat Diagn
Pays: England
ID NLM: 8106540
Informations de publication
Date de publication:
07 2020
07 2020
Historique:
received:
14
01
2020
revised:
22
02
2020
accepted:
03
03
2020
pubmed:
12
4
2020
medline:
14
7
2021
entrez:
12
4
2020
Statut:
ppublish
Résumé
The purpose of this study was to establish prognostic factors in fetuses diagnosed with periventricular pseudocysts (PVPCs) without known congenital infection, between 28 and 37 weeks of gestation. This retrospective study included cases of fetal PVPC from 2008 to 2018. PVPCs were classified according to location, number, extension, morphology, and size. Additional findings, MRI and genetic studies were recorded. Pregnancy outcome, postnatal, or postmortem results were obtained. Images from patients with normal (Group 1) and abnormal postnatal development (Group 2) were compared for analysis of factors predictive of outcome. One-hundred and fifteen pseudocysts were observed in 59 patients. In 34 fetuses (57%), the PVPC was an isolated finding. Thirty-nine patients delivered live newborns, 27% opted for termination of pregnancy, and 4 patients were lost to follow-up. Eighty-four percent of the liveborns had normal development. When assessing for the influence of pseudocyst characteristics, a wide CSP, or large head circumference, neither of these affected the outcome. The presence of additional anomalies was the only positive predictor for abnormal development regradless of specific PVPC characteristics (P = .002). In fetuses with PVPCs, the presence of additional anomalies was the only predictor for adverse postnatal outcome. No association between cystic characteristics and adverse outcome was observed.
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
931-941Informations de copyright
© 2020 John Wiley & Sons, Ltd.
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