Predicting risk of low birth weight offspring from maternal features and blood polycyclic aromatic hydrocarbon concentration.
Assam
Low birth weight
POPs
Polycyclic aromatic hydrocarbons
Pregnancy outcome
Journal
Reproductive toxicology (Elmsford, N.Y.)
ISSN: 1873-1708
Titre abrégé: Reprod Toxicol
Pays: United States
ID NLM: 8803591
Informations de publication
Date de publication:
06 2020
06 2020
Historique:
received:
19
01
2020
revised:
26
03
2020
accepted:
31
03
2020
pubmed:
14
4
2020
medline:
24
2
2021
entrez:
14
4
2020
Statut:
ppublish
Résumé
Prenatal exposure to organic pollutants increases the risk of low birth weight (LBW) offspring. Women involved in the plucking of tea leaves can be exposed to polycyclic aromatic hydrocarbons (PAHs) during pregnancy through inhalation and diet. Therefore, the aim of the study was to investigate the association of maternal socio-demographic features and blood PAH concentration with LBW; also to develop a model for predicting LBW risk. The study was performed by recruiting 55 women who delivered LBW and 120 women with NBW (normal birth weight) babies from Assam Medical College. The placental tissue, maternal and cord blood samples were collected. A total of sixteen PAHs and cotinine were analysed by HPLC and GC-MS. Association of PAH concentration with weight was determined using correlation and multiple logistic regression analyses. Predictive model was developed using SVM
Identifiants
pubmed: 32283251
pii: S0890-6238(20)30048-4
doi: 10.1016/j.reprotox.2020.03.009
pii:
doi:
Substances chimiques
Environmental Pollutants
0
Polycyclic Aromatic Hydrocarbons
0
Cotinine
K5161X06LL
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
92-100Informations de copyright
Copyright © 2020 Elsevier Inc. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of Competing Interest No potential conflict of interest was reported by the authors.