Relation of Advanced Interatrial Block to Risk of Atrial Fibrillation and Stroke.
Journal
The American journal of cardiology
ISSN: 1879-1913
Titre abrégé: Am J Cardiol
Pays: United States
ID NLM: 0207277
Informations de publication
Date de publication:
01 06 2020
01 06 2020
Historique:
received:
13
12
2019
revised:
26
02
2020
accepted:
27
02
2020
pubmed:
15
4
2020
medline:
29
8
2020
entrez:
15
4
2020
Statut:
ppublish
Résumé
Advanced interatrial block (A-IAB) has been associated to atrial fibrillation (AF) and ischemic stroke, raising the question as to whether such patients, even when still in sinus rhythm without documented AF, could benefit from oral anticoagulation. AF and A-IAB are both markers of stroke. The anatomical substrate in both is fibrotic atrial cardiomyopathy, resulting in atrial electromechanical dyssynchrony, dysfunction, and left atrial remodelling, that favour blood stasis and hypercoagulation. Under these conditions thrombogenic cascade may be triggered, resulting in systemic embolization. Before proposing oral anticoagulation in the management of selected patients with A-IAB, as is currently recommended in patients with AF and high CHA
Identifiants
pubmed: 32284175
pii: S0002-9149(20)30208-3
doi: 10.1016/j.amjcard.2020.02.034
pii:
doi:
Substances chimiques
Anticoagulants
0
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
1745-1748Informations de copyright
Copyright © 2020 Elsevier Inc. All rights reserved.