Salt Taste Genotype, Dietary Habits and Biomarkers of Health: No Associations in an Elderly Cohort.
Aged
Aged, 80 and over
Biomarkers
Cardiovascular Diseases
/ etiology
Cohort Studies
Eating
/ genetics
Feeding Behavior
/ physiology
Female
Health Status
Health Status Indicators
Humans
Hypertension
/ etiology
Male
Polymorphism, Single Nucleotide
Risk Factors
Sensory Receptor Cells
Sodium Chloride, Dietary
TRPV Cation Channels
/ genetics
Taste
/ genetics
TRPV1 gene
biomarker
dietary
elderly
nutrigenetics
rs806500
salt
taste
Journal
Nutrients
ISSN: 2072-6643
Titre abrégé: Nutrients
Pays: Switzerland
ID NLM: 101521595
Informations de publication
Date de publication:
10 Apr 2020
10 Apr 2020
Historique:
received:
29
02
2020
revised:
01
04
2020
accepted:
08
04
2020
entrez:
16
4
2020
pubmed:
16
4
2020
medline:
12
1
2021
Statut:
epublish
Résumé
A small amount of emerging research has observed variations between individual sensitivity, preference and intake of salt in the presence of single nucleotide polymorphisms (SNP) on the genes encoding salt taste receptors. Sodium intake is a significant risk factor for common diseases in elderly populations such as hypertension and cardiovascular disease; however, this does not fully explain the risk. Research into the influence of salt taste genetics on diet quality is yet to be undertaken and current research on indicators of health is limited and mixed in the direction of associations. Therefore, a secondary analysis of data from a well-characterised elderly cohort (the cross-sectional Retirement Health and Lifestyle Study,
Identifiants
pubmed: 32290310
pii: nu12041056
doi: 10.3390/nu12041056
pmc: PMC7231396
pii:
doi:
Substances chimiques
Biomarkers
0
Sodium Chloride, Dietary
0
TRPV Cation Channels
0
TRPV1 protein, human
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : Australian Research Council
ID : G0188386
Organisme : Central Coast Local Health District
ID : G0190658/G1700259
Organisme : UnitingCare Aging
ID : G0189230
Organisme : Urbis Pty Ltd
ID : G0189232
Organisme : Valhalla Village
ID : G1000936
Organisme : Hunter Valley Research Foundation
ID : N/A
Déclaration de conflit d'intérêts
The authors declare no conflicts of interest.
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