Requirement for cleavage factor II

3' Untranslated Regions / genetics Breast Neoplasms / genetics Cell Line, Tumor Humans MCF-7 Cells Poly A / genetics Polyadenylation / genetics Protein Binding / genetics RNA Polymerase II / genetics RNA Precursors / genetics RNA, Messenger / genetics mRNA Cleavage and Polyadenylation Factors / genetics
alternative polyadenylation breast cancer gene expression pre-mRNA 3′ end formation

Journal

RNA (New York, N.Y.)
ISSN: 1469-9001
Titre abrégé: RNA
Pays: United States
ID NLM: 9509184

Informations de publication

Date de publication:
08 2020
Historique:
received: 27 02 2020
accepted: 09 04 2020
pubmed: 17 4 2020
medline: 6 10 2020
entrez: 17 4 2020
Statut: ppublish

Résumé

Alternative polyadenylation (APA) determines stability, localization and translation potential of the majority of mRNA in eukaryotic cells. The heterodimeric mammalian cleavage factor II (CF II

Identifiants

DOI: 10.1261/rna.075226.120 PMID: 32295865 PMC: PMC7373993
pubmed: 32295865
pii: rna.075226.120
doi: 10.1261/rna.075226.120
pmc: PMC7373993
doi:

Substances chimiques

3' Untranslated Regions 0
RNA Precursors 0
RNA, Messenger 0
cleavage factor Im, human 0
mRNA Cleavage and Polyadenylation Factors 0
Poly A 24937-83-5
RNA Polymerase II EC 2.7.7.-

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

969-981

Informations de copyright

© 2020 Turner et al.; Published by Cold Spring Harbor Laboratory Press for the RNA Society.

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Auteurs

Rachael E Turner (RE)

Development and Stem Cells Program, Monash Biomedicine Discovery Institute and Department of Biochemistry and Molecular Biology, Monash University, Melbourne, Victoria 3800, Australia.

Lee M Henneken (LM)

School of Life and Environmental Sciences, Deakin University, Geelong, Victoria 3220, Australia.

Marije Liem-Weits (M)

School of Life and Environmental Sciences, Deakin University, Geelong, Victoria 3220, Australia.

Paul F Harrison (PF)

Development and Stem Cells Program, Monash Biomedicine Discovery Institute and Department of Biochemistry and Molecular Biology, Monash University, Melbourne, Victoria 3800, Australia.
Monash Bioinformatics Platform, Monash University, Melbourne, Victoria 3800, Australia.

Angavai Swaminathan (A)

Development and Stem Cells Program, Monash Biomedicine Discovery Institute and Department of Biochemistry and Molecular Biology, Monash University, Melbourne, Victoria 3800, Australia.

Robert Vary (R)

Victorian Centre for Functional Genomics, Peter MacCallum Cancer Centre, Melbourne, Victoria 3000, Australia.

Iva Nikolic (I)

Victorian Centre for Functional Genomics, Peter MacCallum Cancer Centre, Melbourne, Victoria 3000, Australia.

Kaylene J Simpson (KJ)

Victorian Centre for Functional Genomics, Peter MacCallum Cancer Centre, Melbourne, Victoria 3000, Australia.
Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville 3010, Australia.

David R Powell (DR)

Monash Bioinformatics Platform, Monash University, Melbourne, Victoria 3800, Australia.

Traude H Beilharz (TH)

Development and Stem Cells Program, Monash Biomedicine Discovery Institute and Department of Biochemistry and Molecular Biology, Monash University, Melbourne, Victoria 3800, Australia.
ORCID: 0000-0002-8942-9502

Bernhard Dichtl (B)

School of Life and Environmental Sciences, Deakin University, Geelong, Victoria 3220, Australia.

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Classifications MeSH

questionsmedicales.fr › Phénomènes génétiques › Structures génétiques › Génome › Composants de génome › Gènes › Composants de gène › Régions non traduites › Régions 3' non traduites › Requirement for cleavage factor II
questionsmedicales.fr › Maladies de la peau et du tissu conjonctif › Maladies de la peau › Maladies du sein › Tumeurs du sein › Requirement for cleavage factor II
questionsmedicales.fr › Cellules › Cellules cultivées › Cellules cancéreuses en culture › Lignée cellulaire tumorale › Requirement for cleavage factor II
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Requirement for cleavage factor II
questionsmedicales.fr › Cellules › Cellules cultivées › Lignée cellulaire › Cellules MCF-7 › Requirement for cleavage factor II
questionsmedicales.fr › Acides nucléiques, nucléotides et nucléosides › Nucléotides › Polynucléotides › Polyribonucléotides › Poly A › Requirement for cleavage factor II
questionsmedicales.fr › Phénomènes génétiques › Régulation de l'expression des gènes › Maturation post-transcriptionnelle des ARN › Maturation de l'extrémité 3' des ARN › Polyadénylation › Requirement for cleavage factor II
questionsmedicales.fr › Métabolisme › Liaison aux protéines › Requirement for cleavage factor II
questionsmedicales.fr › Enzymes et coenzymes › Enzymes › Transferases › Phosphotransferases › Nucleotidyltransferases › RNA nucleotidyltransferases › DNA-directed RNA polymerases › RNA polymerase II › Requirement for cleavage factor II
questionsmedicales.fr › Acides nucléiques, nucléotides et nucléosides › Acides nucléiques › ARN › Précurseurs des ARN › Requirement for cleavage factor II
questionsmedicales.fr › Acides nucléiques, nucléotides et nucléosides › Acides nucléiques › ARN › ARN messager › Requirement for cleavage factor II
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Nucléoprotéines › Protéines de liaison à l'ARN › Facteurs de clivage et de polyadénylation de l'ARN messager › Requirement for cleavage factor II