A reference map of the human binary protein interactome.

Extracellular Space / metabolism Humans Organ Specificity Protein Interaction Mapping Proteome / metabolism

Journal

Nature
ISSN: 1476-4687
Titre abrégé: Nature
Pays: England
ID NLM: 0410462

Informations de publication

Date de publication:
04 2020
Historique:
received: 19 04 2019
accepted: 14 02 2020
entrez: 17 4 2020
pubmed: 17 4 2020
medline: 10 5 2020
Statut: ppublish

Résumé

Global insights into cellular organization and genome function require comprehensive understanding of the interactome networks that mediate genotype-phenotype relationships

Identifiants

DOI: 10.1038/s41586-020-2188-x PMID: 32296183 PMC: PMC7169983
pubmed: 32296183
doi: 10.1038/s41586-020-2188-x
pii: 10.1038/s41586-020-2188-x
pmc: PMC7169983
mid: NIHMS1562320
doi:

Substances chimiques

Proteome 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

402-408

Subventions

Organisme : NHGRI NIH HHS
ID : U01 HG007690
Pays : United States
Organisme : NHGRI NIH HHS
ID : P50 HG004233
Pays : United States
Organisme : NIGMS NIH HHS
ID : R01 GM109199
Pays : United States
Organisme : NHGRI NIH HHS
ID : U41 HG001715
Pays : United States
Organisme : NHLBI NIH HHS
ID : U01 HL098166
Pays : United States
Organisme : NCI NIH HHS
ID : T32 CA009361
Pays : United States

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Auteurs

Katja Luck (K)

Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USA.
Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA.
Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.

Dae-Kyum Kim (DK)

Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USA.
The Donnelly Centre, University of Toronto, Toronto, Ontario, Canada.
Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.
Lunenfeld-Tanenbaum Research Institute (LTRI), Sinai Health System, Toronto, Ontario, Canada.

Luke Lambourne (L)

Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USA.
Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA.
Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.
ORCID: 0000-0002-7001-7575

Kerstin Spirohn (K)

Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USA.
Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA.
Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.
ORCID: 0000-0002-2071-1606

Bridget E Begg (BE)

Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USA.
Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA.
Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.

Wenting Bian (W)

Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USA.
Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA.
Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.

Ruth Brignall (R)

Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USA.
Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA.
Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.

Tiziana Cafarelli (T)

Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USA.
Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA.
Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.

Francisco J Campos-Laborie (FJ)

Cancer Research Center (CiC-IBMCC, CSIC/USAL), Consejo Superior de Investigaciones Científicas (CSIC) and University of Salamanca (USAL), Salamanca, Spain.
Institute for Biomedical Research of Salamanca (IBSAL), Salamanca, Spain.

Benoit Charloteaux (B)

Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USA.
Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA.
Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.

Dongsic Choi (D)

The Research Institute of the McGill University Health Centre (RI-MUHC), Montreal, Quebec, Canada.

Atina G Coté (AG)

Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USA.
The Donnelly Centre, University of Toronto, Toronto, Ontario, Canada.
Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.
Lunenfeld-Tanenbaum Research Institute (LTRI), Sinai Health System, Toronto, Ontario, Canada.

Meaghan Daley (M)

Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USA.
Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA.
Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.

Steven Deimling (S)

Department of Cell and Systems Biology, University of Toronto, Toronto, Ontario, Canada.

Alice Desbuleux (A)

Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USA.
Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA.
Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.
Molecular Biology of Diseases, Groupe Interdisciplinaire de Génomique Appliquée (GIGA) and Laboratory of Viral Interactomes, University of Liège, Liège, Belgium.

Amélie Dricot (A)

Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USA.
Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA.
Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.

Marinella Gebbia (M)

Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USA.
The Donnelly Centre, University of Toronto, Toronto, Ontario, Canada.
Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.
Lunenfeld-Tanenbaum Research Institute (LTRI), Sinai Health System, Toronto, Ontario, Canada.

Madeleine F Hardy (MF)

Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USA.
Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA.
Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.

Nishka Kishore (N)

Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USA.
The Donnelly Centre, University of Toronto, Toronto, Ontario, Canada.
Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.
Lunenfeld-Tanenbaum Research Institute (LTRI), Sinai Health System, Toronto, Ontario, Canada.

Jennifer J Knapp (JJ)

Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USA.
The Donnelly Centre, University of Toronto, Toronto, Ontario, Canada.
Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.
Lunenfeld-Tanenbaum Research Institute (LTRI), Sinai Health System, Toronto, Ontario, Canada.

István A Kovács (IA)

Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USA.
Network Science Institute, Northeastern University, Boston, MA, USA.
Wigner Research Centre for Physics, Institute for Solid State Physics and Optics, Budapest, Hungary.

Irma Lemmens (I)

Center for Medical Biotechnology, Vlaams Instituut voor Biotechnologie (VIB), Ghent, Belgium.
Cytokine Receptor Laboratory (CRL), Department of Biomolecular Medicine, Faculty of Medicine and Health Sciences, Ghent University, Ghent, Belgium.

Miles W Mee (MW)

The Donnelly Centre, University of Toronto, Toronto, Ontario, Canada.
Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.
Department of Computer Science, University of Toronto, Toronto, Ontario, Canada.

Joseph C Mellor (JC)

Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USA.
The Donnelly Centre, University of Toronto, Toronto, Ontario, Canada.
Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.
Lunenfeld-Tanenbaum Research Institute (LTRI), Sinai Health System, Toronto, Ontario, Canada.
seqWell, Beverly, MA, USA.

Carl Pollis (C)

Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USA.
Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA.
Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.

Carles Pons (C)

Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute for Science and Technology, Barcelona, Catalonia, Spain.

Aaron D Richardson (AD)

Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USA.
Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA.
Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.

Sadie Schlabach (S)

Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USA.
Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA.
Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.

Bridget Teeking (B)

Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USA.
Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA.
Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.

Anupama Yadav (A)

Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USA.
Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA.
Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.
ORCID: 0000-0001-5338-0455

Mariana Babor (M)

Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USA.
The Donnelly Centre, University of Toronto, Toronto, Ontario, Canada.
Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.
Lunenfeld-Tanenbaum Research Institute (LTRI), Sinai Health System, Toronto, Ontario, Canada.

Dawit Balcha (D)

Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USA.
Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA.
Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.

Omer Basha (O)

Department of Clinical Biochemistry and Pharmacology, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel.
National Institute for Biotechnology in the Negev (NIBN), Ben-Gurion University of the Negev, Beer-Sheva, Israel.

Christian Bowman-Colin (C)

Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA.
Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.

Suet-Feung Chin (SF)

Cancer Research UK (CRUK) Cambridge Institute, University of Cambridge, Cambridge, UK.
ORCID: 0000-0001-5697-1082

Soon Gang Choi (SG)

Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USA.
Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA.
Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.
ORCID: 0000-0003-0314-3958

Claudia Colabella (C)

Department of Pharmaceutical Sciences, University of Perugia, Perugia, Italy.
Istituto Zooprofilattico Sperimentale dell'Umbria e delle Marche "Togo Rosati" (IZSUM), Perugia, Italy.
ORCID: 0000-0002-2156-4150

Georges Coppin (G)

Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USA.
Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA.
Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.
Molecular Biology of Diseases, Groupe Interdisciplinaire de Génomique Appliquée (GIGA) and Laboratory of Viral Interactomes, University of Liège, Liège, Belgium.

Cassandra D'Amata (C)

Department of Cell and Systems Biology, University of Toronto, Toronto, Ontario, Canada.

David De Ridder (D)

Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USA.
Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA.
Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.

Steffi De Rouck (S)

Center for Medical Biotechnology, Vlaams Instituut voor Biotechnologie (VIB), Ghent, Belgium.
Cytokine Receptor Laboratory (CRL), Department of Biomolecular Medicine, Faculty of Medicine and Health Sciences, Ghent University, Ghent, Belgium.

Miquel Duran-Frigola (M)

Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute for Science and Technology, Barcelona, Catalonia, Spain.

Hanane Ennajdaoui (H)

Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USA.
The Donnelly Centre, University of Toronto, Toronto, Ontario, Canada.
Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.
Lunenfeld-Tanenbaum Research Institute (LTRI), Sinai Health System, Toronto, Ontario, Canada.

Florian Goebels (F)

The Donnelly Centre, University of Toronto, Toronto, Ontario, Canada.
Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.
Department of Computer Science, University of Toronto, Toronto, Ontario, Canada.

Liana Goehring (L)

Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA.
Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.

Anjali Gopal (A)

Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USA.
The Donnelly Centre, University of Toronto, Toronto, Ontario, Canada.
Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.
Lunenfeld-Tanenbaum Research Institute (LTRI), Sinai Health System, Toronto, Ontario, Canada.

Ghazal Haddad (G)

Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USA.
The Donnelly Centre, University of Toronto, Toronto, Ontario, Canada.
Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.
Lunenfeld-Tanenbaum Research Institute (LTRI), Sinai Health System, Toronto, Ontario, Canada.

Elodie Hatchi (E)

Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA.
Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.

Mohamed Helmy (M)

The Donnelly Centre, University of Toronto, Toronto, Ontario, Canada.
Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.
Department of Computer Science, University of Toronto, Toronto, Ontario, Canada.
ORCID: 0000-0002-9561-7956

Yves Jacob (Y)

Département de Virologie, Unité de Génétique Moléculaire des Virus à ARN (GMVR), Institut Pasteur, UMR3569, Centre National de la Recherche Scientifique (CNRS), Paris, France.
Université Paris Diderot, Paris, France.
ORCID: 0000-0001-9125-2374

Yoseph Kassa (Y)

Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USA.
Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA.
Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.

Serena Landini (S)

Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA.
Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.

Roujia Li (R)

Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USA.
The Donnelly Centre, University of Toronto, Toronto, Ontario, Canada.
Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.
Lunenfeld-Tanenbaum Research Institute (LTRI), Sinai Health System, Toronto, Ontario, Canada.

Natascha van Lieshout (N)

Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USA.
The Donnelly Centre, University of Toronto, Toronto, Ontario, Canada.
Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.
Lunenfeld-Tanenbaum Research Institute (LTRI), Sinai Health System, Toronto, Ontario, Canada.

Andrew MacWilliams (A)

Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USA.
Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA.
Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.

Dylan Markey (D)

Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USA.
Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA.
Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.

Joseph N Paulson (JN)

Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Boston, MA, USA.
Department of Biostatistics, Harvard School of Public Health, Boston, MA, USA.
Department of Biostatistics, Product Development, Genentech Inc., South San Francisco, CA, USA.
ORCID: 0000-0001-8221-7139

Sudharshan Rangarajan (S)

Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USA.
Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA.
Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.

John Rasla (J)

Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USA.
Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA.
Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.

Ashyad Rayhan (A)

Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USA.
The Donnelly Centre, University of Toronto, Toronto, Ontario, Canada.
Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.
Lunenfeld-Tanenbaum Research Institute (LTRI), Sinai Health System, Toronto, Ontario, Canada.

Thomas Rolland (T)

Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USA.
Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA.
Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.

Adriana San-Miguel (A)

Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USA.
Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA.
Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.

Yun Shen (Y)

Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USA.
Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA.
Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.

Dayag Sheykhkarimli (D)

Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USA.
The Donnelly Centre, University of Toronto, Toronto, Ontario, Canada.
Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.
Lunenfeld-Tanenbaum Research Institute (LTRI), Sinai Health System, Toronto, Ontario, Canada.
ORCID: 0000-0001-8415-6659

Gloria M Sheynkman (GM)

Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USA.
Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA.
Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.

Eyal Simonovsky (E)

Department of Clinical Biochemistry and Pharmacology, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel.
National Institute for Biotechnology in the Negev (NIBN), Ben-Gurion University of the Negev, Beer-Sheva, Israel.

Murat Taşan (M)

Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USA.
The Donnelly Centre, University of Toronto, Toronto, Ontario, Canada.
Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.
Lunenfeld-Tanenbaum Research Institute (LTRI), Sinai Health System, Toronto, Ontario, Canada.
Department of Computer Science, University of Toronto, Toronto, Ontario, Canada.

Alexander Tejeda (A)

Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USA.
Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA.
Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.

Vincent Tropepe (V)

Department of Cell and Systems Biology, University of Toronto, Toronto, Ontario, Canada.

Jean-Claude Twizere (JC)

Molecular Biology of Diseases, Groupe Interdisciplinaire de Génomique Appliquée (GIGA) and Laboratory of Viral Interactomes, University of Liège, Liège, Belgium.
ORCID: 0000-0002-8683-705X

Yang Wang (Y)

Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USA.
Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA.
Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.

Robert J Weatheritt (RJ)

The Donnelly Centre, University of Toronto, Toronto, Ontario, Canada.

Jochen Weile (J)

Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USA.
The Donnelly Centre, University of Toronto, Toronto, Ontario, Canada.
Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.
Lunenfeld-Tanenbaum Research Institute (LTRI), Sinai Health System, Toronto, Ontario, Canada.
Department of Computer Science, University of Toronto, Toronto, Ontario, Canada.

Yu Xia (Y)

Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USA.
Department of Bioengineering, McGill University, Montreal, Quebec, Canada.
ORCID: 0000-0002-5596-5518

Xinping Yang (X)

Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USA.
Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA.
Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.

Esti Yeger-Lotem (E)

Department of Clinical Biochemistry and Pharmacology, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel.
National Institute for Biotechnology in the Negev (NIBN), Ben-Gurion University of the Negev, Beer-Sheva, Israel.
ORCID: 0000-0002-8279-7898

Quan Zhong (Q)

Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USA.
Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA.
Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.
Department of Biological Sciences, Wright State University, Dayton, OH, USA.
ORCID: 0000-0003-2910-5597

Patrick Aloy (P)

Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute for Science and Technology, Barcelona, Catalonia, Spain.
Institució Catalana de Recerca i Estudis Avançats (ICREA), Barcelona, Catalonia, Spain.

Gary D Bader (GD)

The Donnelly Centre, University of Toronto, Toronto, Ontario, Canada.
Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.
Department of Computer Science, University of Toronto, Toronto, Ontario, Canada.
ORCID: 0000-0003-0185-8861

Javier De Las Rivas (J)

Cancer Research Center (CiC-IBMCC, CSIC/USAL), Consejo Superior de Investigaciones Científicas (CSIC) and University of Salamanca (USAL), Salamanca, Spain.
Institute for Biomedical Research of Salamanca (IBSAL), Salamanca, Spain.
ORCID: 0000-0002-0984-9946

Suzanne Gaudet (S)

Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USA.
Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA.
Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.

Tong Hao (T)

Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USA.
Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA.
Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.
ORCID: 0000-0001-7908-3256

Janusz Rak (J)

The Research Institute of the McGill University Health Centre (RI-MUHC), Montreal, Quebec, Canada.
ORCID: 0000-0002-2912-5566

Jan Tavernier (J)

Center for Medical Biotechnology, Vlaams Instituut voor Biotechnologie (VIB), Ghent, Belgium.
Cytokine Receptor Laboratory (CRL), Department of Biomolecular Medicine, Faculty of Medicine and Health Sciences, Ghent University, Ghent, Belgium.

David E Hill (DE)

Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USA. david_hill@dfci.harvard.edu.
Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA. david_hill@dfci.harvard.edu.
Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA. david_hill@dfci.harvard.edu.
ORCID: 0000-0001-5192-0921

Marc Vidal (M)

Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USA. marc_vidal@dfci.harvard.edu.
Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA. marc_vidal@dfci.harvard.edu.

Frederick P Roth (FP)

Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USA. fritz.roth@utoronto.ca.
The Donnelly Centre, University of Toronto, Toronto, Ontario, Canada. fritz.roth@utoronto.ca.
Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada. fritz.roth@utoronto.ca.
Lunenfeld-Tanenbaum Research Institute (LTRI), Sinai Health System, Toronto, Ontario, Canada. fritz.roth@utoronto.ca.
Department of Computer Science, University of Toronto, Toronto, Ontario, Canada. fritz.roth@utoronto.ca.
Canadian Institute for Advanced Research (CIFAR), Toronto, Ontario, Canada. fritz.roth@utoronto.ca.
ORCID: 0000-0002-6628-649X

Michael A Calderwood (MA)

Center for Cancer Systems Biology (CCSB), Dana-Farber Cancer Institute, Boston, MA, USA. michael_calderwood@dfci.harvard.edu.
Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA. michael_calderwood@dfci.harvard.edu.
Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA. michael_calderwood@dfci.harvard.edu.
ORCID: 0000-0001-6475-1418

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Classifications MeSH

questionsmedicales.fr › Cellules › Structures cellulaires › Espace extracellulaire › A reference map of the human binary protein...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › A reference map of the human binary protein...
questionsmedicales.fr › Phénomènes physiologiques › Spécificité d'organe › A reference map of the human binary protein...
questionsmedicales.fr › Techniques d'investigation › Techniques de sonde moléculaire › Cartographie d'interactions entre protéines › A reference map of the human binary protein...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéome › A reference map of the human binary protein...