Cold intolerance and neuropathic pain after peripheral nerve injury in upper extremity.
Adult
Cold Temperature
Cross-Sectional Studies
Female
Humans
Male
Microsurgery
Middle Aged
Neuralgia
/ etiology
Neurological Rehabilitation
Neurosurgical Procedures
Peripheral Nerve Injuries
/ complications
Severity of Illness Index
Somatosensory Disorders
/ etiology
Upper Extremity
/ physiopathology
cold intolerance
nerve repair
neuropathic pain
peripheral nerve injury
sensory re-education
Journal
Journal of the peripheral nervous system : JPNS
ISSN: 1529-8027
Titre abrégé: J Peripher Nerv Syst
Pays: United States
ID NLM: 9704532
Informations de publication
Date de publication:
06 2020
06 2020
Historique:
received:
20
01
2020
revised:
28
03
2020
accepted:
05
04
2020
pubmed:
17
4
2020
medline:
2
6
2021
entrez:
17
4
2020
Statut:
ppublish
Résumé
Cold intolerance and pain can be a substantial problem in patients with peripheral nerve injury. We aimed at investigating the relationships among sensory recovery, cold intolerance, and neuropathic pain in patients affected by upper limb peripheral nerve injury (Sunderland type V) treated with microsurgical repair, followed by early sensory re-education. In a cross-sectional clinical study, 100 patients (male/female 81/19; age 40.5 ± 14.8 years and follow-up 17 ± 5 months, mean ± SD), with microsurgical nerve repair and reconstruction in the upper extremity and subsequent early sensory re-education, were evaluated, using Cold Intolerance Symptoms Severity questionnaire-Italian version (CISS-it, cut-off pathology >30/100 points), CISS questionnaire-12 item version (CISS-12, 0-46 points-grouping: healthy that means no cold intolerance [0-14], mild [15-24], moderate [25-34], severe [35-42], very severe [43-46] cold intolerance), probability of neuropathic pain (DouleurNeuropathique-4; [DN4] 4/10), deep and superficial sensibility, tactile threshold (monofilaments), and two-point discrimination (cutoff S2; Medical Research Council scale for sensory function; [MRC-scale]). A high CISS score is associated with possible neuropathic pain (DN4 ≥ 4). Both a low CISS-it score (ie, < 30) and DN4 < 4 is associated with good sensory recovery (MRC ≥ 2). In conclusion patients affected by upper limb peripheral nerve injuries with higher CISS scores more often suffer from cold intolerance and neuropathic pain, and the better their sensory recovery is, the less likely they are to suffer from cold intolerance and neuropathic pain.
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
184-190Informations de copyright
© 2020 Peripheral Nerve Society.
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