Cyclic regulation of Trpm4 expression in female vomeronasal neurons driven by ovarian sex hormones.
Action Potentials
/ physiology
Animals
Calcium
/ metabolism
Diglycerides
/ metabolism
Estradiol
/ metabolism
Estrogens
/ metabolism
Female
Male
Mice
Ovary
/ metabolism
Sensory Receptor Cells
/ metabolism
TRPC Cation Channels
/ genetics
TRPM Cation Channels
/ metabolism
Vomeronasal Organ
/ metabolism
Aromatase
Exemestane
Olfactory
Pheromone sensing
Trpm4-IRES-Cre
Trpm5
Journal
Molecular and cellular neurosciences
ISSN: 1095-9327
Titre abrégé: Mol Cell Neurosci
Pays: United States
ID NLM: 9100095
Informations de publication
Date de publication:
06 2020
06 2020
Historique:
received:
05
11
2019
revised:
13
03
2020
accepted:
11
04
2020
pubmed:
17
4
2020
medline:
4
3
2021
entrez:
17
4
2020
Statut:
ppublish
Résumé
The vomeronasal organ (VNO), the sensory organ of the mammalian accessory olfactory system, mediates the activation of sexually dimorphic reproductive behavioral and endocrine responses in males and females. It is unclear how sexually dimorphic and state-dependent responses are generated by vomeronasal sensory neurons (VSNs). Here, we report the expression of the transient receptor potential (TRP) channel Trpm4, a Ca
Identifiants
pubmed: 32298804
pii: S1044-7431(19)30299-4
doi: 10.1016/j.mcn.2020.103495
pii:
doi:
Substances chimiques
Diglycerides
0
Estrogens
0
TRPC Cation Channels
0
TRPM Cation Channels
0
TRPM4 protein, mouse
0
Estradiol
4TI98Z838E
Calcium
SY7Q814VUP
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
103495Informations de copyright
Copyright © 2020 The Authors. Published by Elsevier Inc. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of competing interest The authors declare no conflict of interest.