What Do We Know About Clodronate Now? A Medical and Veterinary Perspective.

Animals Clodronic Acid / therapeutic use Diphosphonates / adverse effects Horses
Bisphosphonate Clodronate Horse Lameness Navicular syndrome Osteoarthritis

Journal

Journal of equine veterinary science
ISSN: 0737-0806
Titre abrégé: J Equine Vet Sci
Pays: United States
ID NLM: 8216840

Informations de publication

Date de publication:
05 2020
Historique:
received: 12 08 2019
revised: 18 11 2019
accepted: 19 11 2019
entrez: 19 4 2020
pubmed: 19 4 2020
medline: 23 1 2021
Statut: ppublish

Résumé

There has recently been some controversy over the use of bisphosphonates in horses and some confusion regarding the different classes of bisphosphonates and the differences between the mechanism of actions and effects of each class. This review article explores the different bisphosphonate classes and their different effects and mechanisms of action based on research from both the human and equine veterinary fields. This collaborative review between veterinary surgeons and medical doctors describes the latest use of bisphosphonates in humans and horses, including safety aspects, and allows comparisons to be drawn between the two fields. Potential future uses of bisphosphonates are also discussed.

Identifiants

DOI: 10.1016/j.jevs.2019.102874 PMID: 32303308
pubmed: 32303308
pii: S0737-0806(19)30623-9
doi: 10.1016/j.jevs.2019.102874
pii:
doi:

Substances chimiques

Diphosphonates 0
Clodronic Acid 0813BZ6866

Types de publication

Journal Article Research Support, Non-U.S. Gov't Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

102874

Informations de copyright

Copyright © 2019 The Authors. Published by Elsevier Inc. All rights reserved.

Auteurs

Richard Markell (R)

Ranch & Coast Equine Practice, Inc, Bonsall, CA; IlluminX Consulting Inc, Bonsall, CA.

Gianantonio Saviola (G)

Istituti Clinici Scientifici Maugeri IRCCS, Rheumatology and Rehabilitation Unit of the Institute of Castel Goffredo, Mantua, Italy.

Elizabeth Ann Barker (EA)

Dechra Veterinary Products EU, Shrewsbury, UK. Electronic address: lizzie.barker@dechra.com.

James Daniel Conway (JD)

Dechra Veterinary Products US, Overland Park, KS.

Chris Dujardin (C)

Dechra Veterinary Products EU, 's-Hertogenbosch, Netherlands.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › What Do We Know About Clodronate Now? A...
questionsmedicales.fr › Composés chimiques organiques › Composés organiques du phosphore › Phosphonates › Diphosphonates › Acide clodronique › What Do We Know About Clodronate Now? A...
questionsmedicales.fr › Composés chimiques organiques › Composés organiques du phosphore › Phosphonates › Diphosphonates › What Do We Know About Clodronate Now? A...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Perissodactyla › Equidae › Equus caballus › What Do We Know About Clodronate Now? A...