Dietary nitrate does not acutely enhance skeletal muscle blood flow and vasodilation in the lower limbs of older adults during single-limb exercise.
Aged
Blood Pressure
/ physiology
Composite Resins
Double-Blind Method
Exercise
/ physiology
Female
Femoral Artery
/ diagnostic imaging
Glass Ionomer Cements
Heart Rate
/ physiology
Hemodynamics
/ physiology
Humans
Lower Extremity
/ blood supply
Male
Muscle Contraction
/ physiology
Muscle, Skeletal
/ blood supply
Nitrates
/ administration & dosage
Regional Blood Flow
/ physiology
Ultrasonography, Doppler
Vasodilation
/ physiology
Aging
Blood flow
Dietary nitrate
Nitric oxide
Vasodilator kinetics
Journal
European journal of applied physiology
ISSN: 1439-6327
Titre abrégé: Eur J Appl Physiol
Pays: Germany
ID NLM: 100954790
Informations de publication
Date de publication:
Jun 2020
Jun 2020
Historique:
received:
03
12
2019
accepted:
05
04
2020
pubmed:
19
4
2020
medline:
18
3
2021
entrez:
19
4
2020
Statut:
ppublish
Résumé
Blood flow (BF) and vasodilator responses to knee-extension exercise are attenuated in older adults across an exercise transient (onset, kinetics, and steady-state), and reduced nitric oxide bioavailability (NO) has been hypothesized to be a primary mechanism contributing to this attenuation. We tested the hypothesis acute dietary nitrate (NO Older (n = 10) untrained adults performed single and rhythmic knee-extension contractions at 20% and 40% work-rate maximum (WR Acute ingestion of dietary NO The key findings of this study are that despite increasing plasma [NO
Identifiants
pubmed: 32303829
doi: 10.1007/s00421-020-04368-8
pii: 10.1007/s00421-020-04368-8
doi:
Substances chimiques
Composite Resins
0
Duet cement
0
Glass Ionomer Cements
0
Nitrates
0
Types de publication
Journal Article
Randomized Controlled Trial
Langues
eng
Sous-ensembles de citation
IM
Pagination
1357-1369Subventions
Organisme : American Diabetes Association
ID : 1-16-1CTA-015
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