Voltage-Dependent Protonation of the Calcium Pocket Enable Activation of the Calcium-Activated Chloride Channel Anoctamin-1 (TMEM16A).
Action Potentials
/ drug effects
Animals
Anoctamin-1
/ antagonists & inhibitors
Anthracenes
/ pharmacology
Calcium
/ metabolism
Cations, Divalent
Chlorides
/ metabolism
Genes, Reporter
Green Fluorescent Proteins
/ genetics
HEK293 Cells
Humans
Ion Channel Gating
/ drug effects
Ion Transport
/ drug effects
Mice
Mutation
Patch-Clamp Techniques
Plasmids
/ chemistry
Protons
Recombinant Fusion Proteins
/ genetics
Structure-Activity Relationship
Tannins
/ pharmacology
Transfection
Journal
Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288
Informations de publication
Date de publication:
20 04 2020
20 04 2020
Historique:
received:
19
02
2020
accepted:
21
03
2020
entrez:
22
4
2020
pubmed:
22
4
2020
medline:
1
12
2020
Statut:
epublish
Résumé
Anoctamin-1 (ANO1 or TMEM16A) is a homo-dimeric Ca
Identifiants
pubmed: 32313203
doi: 10.1038/s41598-020-62860-9
pii: 10.1038/s41598-020-62860-9
pmc: PMC7170896
doi:
Substances chimiques
ANO1 protein, mouse
0
Anoctamin-1
0
Anthracenes
0
Cations, Divalent
0
Chlorides
0
Protons
0
Recombinant Fusion Proteins
0
Tannins
0
enhanced green fluorescent protein
0
Green Fluorescent Proteins
147336-22-9
9-anthroic acid
723-62-6
Calcium
SY7Q814VUP
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
6644Références
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