Human Serum Albumin Facilitates Heme-Iron Utilization by Fungi.
Candida albicans
heme transport
iron acquisition
mycology
Journal
mBio
ISSN: 2150-7511
Titre abrégé: mBio
Pays: United States
ID NLM: 101519231
Informations de publication
Date de publication:
21 04 2020
21 04 2020
Historique:
entrez:
23
4
2020
pubmed:
23
4
2020
medline:
20
11
2020
Statut:
epublish
Résumé
A large portion of biological iron is found in the form of an iron-protoporphyrin IX complex, or heme. In the human host environment, which is exceptionally poor in free iron, heme iron, particularly from hemoglobin, constitutes a major source of iron for invading microbial pathogens. Several fungi were shown to utilize free heme, and
Identifiants
pubmed: 32317324
pii: mBio.00607-20
doi: 10.1128/mBio.00607-20
pmc: PMC7175094
pii:
doi:
Substances chimiques
Hemoglobins
0
Heme
42VZT0U6YR
Iron
E1UOL152H7
Serum Albumin, Human
ZIF514RVZR
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Informations de copyright
Copyright © 2020 Pinsky et al.
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