Exploring the conformational transition between the fully folded and locally unfolded substates of Escherichia coli thiol peroxidase.

Computer Simulation Escherichia coli / chemistry Escherichia coli Proteins / chemistry Molecular Dynamics Simulation Mutation / genetics Periplasmic Proteins / chemistry Peroxidases / chemistry Protein Conformation Protein Folding

Journal

Physical chemistry chemical physics : PCCP
ISSN: 1463-9084
Titre abrégé: Phys Chem Chem Phys
Pays: England
ID NLM: 100888160

Informations de publication

Date de publication:
07 May 2020
Historique:
pubmed: 23 4 2020
medline: 11 8 2020
entrez: 23 4 2020
Statut: ppublish

Résumé

Thiol peroxidase from Escherichia coli (EcTPx) is a peroxiredoxin that catalyzes the reduction of different hydroperoxides. During the catalytic cycle of EcTPx, the peroxidatic cysteine (C

Identifiants

DOI: 10.1039/d0cp00140f PMID: 32319475
pubmed: 32319475
doi: 10.1039/d0cp00140f
doi:

Substances chimiques

Escherichia coli Proteins 0
Periplasmic Proteins 0
Peroxidases EC 1.11.1.-
Tpx protein, E coli EC 1.11.1.-

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

9518-9533

Auteurs

Diego S Vazquez (DS)

Laboratorio de Expresión y Plegado de Proteínas, Departamento de Ciencia y Tecnología, Universidad Nacional de Quilmes, Roque Sáenz Peña 352 (B1876BXD), Bernal, Buenos Aires, Argentina. dsvazquez86@gmail.com.

Ari Zeida (A)

William A Agudelo (WA)

Mónica R Montes (MR)

Gerardo Ferrer-Sueta (G)

Javier Santos (J)

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Classifications MeSH

questionsmedicales.fr › Sciences de l'information › Méthodologies informatiques › Simulation numérique › Exploring the conformational transition...
questionsmedicales.fr › Bactéries › Proteobacteria › Gammaproteobacteria › Enterobacteriaceae › Escherichia › Escherichia coli › Exploring the conformational transition...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines bactériennes › Protéines Escherichia coli › Exploring the conformational transition...
questionsmedicales.fr › Sciences de l'information › Méthodologies informatiques › Simulation numérique › Simulation de dynamique moléculaire › Exploring the conformational transition...
questionsmedicales.fr › Phénomènes génétiques › Variation génétique › Mutation › Exploring the conformational transition...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines végétales › Protéines périplasmiques › Exploring the conformational transition...
questionsmedicales.fr › Enzymes et coenzymes › Enzymes › Oxidoreductases › Peroxidases › Exploring the conformational transition...
questionsmedicales.fr › Phénomènes chimiques › Phénomènes biochimiques › Conformation moléculaire › Conformation des protéines › Exploring the conformational transition...
questionsmedicales.fr › Phénomènes chimiques › Phénomènes biochimiques › Pliage des protéines › Exploring the conformational transition...