Post-traumatic Curvularia sp. arthritis in an immunocompetent adult.
Accidents, Traffic
Adult
Antifungal Agents
/ therapeutic use
Arthritis, Infectious
/ diagnosis
Ascomycota
/ isolation & purification
Fatal Outcome
Female
France
Humans
Immunocompetence
Knee Injuries
/ complications
Knee Joint
/ microbiology
Mali
Mycoses
/ complications
Quadriplegia
/ etiology
Spinal Cord Injuries
/ complications
Travel-Related Illness
Antifungals
Black fungi
Curvularia aeria
Fungal arthritis
Journal
Journal de mycologie medicale
ISSN: 1773-0449
Titre abrégé: J Mycol Med
Pays: France
ID NLM: 9425651
Informations de publication
Date de publication:
Jun 2020
Jun 2020
Historique:
received:
16
10
2019
revised:
08
01
2020
accepted:
31
03
2020
pubmed:
24
4
2020
medline:
21
10
2020
entrez:
24
4
2020
Statut:
ppublish
Résumé
A 44-year-old woman, victim of a road accident in Mali was diagnosed with left knee arthritis. Joint effusion aspiration and subcutaneous surgical biopsies were positive for a melanized asexual ascomycete. Using microscopy and molecular biology, the fungus was identified as Curvularia sp. In vitro antifungal susceptibility was determined by the EUCAST broth microdilution reference technique and by E-test. The patient was treated with liposomal amphotericin B before posaconazole relay. Mycological samples obtained 10 days after starting the antifungal therapy by liposomal amphotericin B were negative in culture. Curvularia spp. are environmental fungi which can under certain conditions be pathogenic for humans.
Identifiants
pubmed: 32321676
pii: S1156-5233(20)30065-2
doi: 10.1016/j.mycmed.2020.100967
pii:
doi:
Substances chimiques
Antifungal Agents
0
Types de publication
Case Reports
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
100967Informations de copyright
Copyright © 2020 Elsevier Masson SAS. All rights reserved.