Single-cell O


Journal

Proceedings of the National Academy of Sciences of the United States of America
ISSN: 1091-6490
Titre abrégé: Proc Natl Acad Sci U S A
Pays: United States
ID NLM: 7505876

Informations de publication

Date de publication:
05 05 2020
Historique:
pubmed: 24 4 2020
medline: 29 7 2020
entrez: 24 4 2020
Statut: ppublish

Résumé

Disorders of oxygen transport are commonly attributed to inadequate carrying capacity (anemia) but may also relate to inefficient gas exchange by red blood cells (RBCs), a process that is poorly characterized yet assumed to be rapid. Without direct measurements of gas exchange at the single-cell level, the barriers to O

Identifiants

pubmed: 32321831
pii: 1916641117
doi: 10.1073/pnas.1916641117
pmc: PMC7211990
doi:

Substances chimiques

Gases 0
Hemoglobins 0
Carbon Dioxide 142M471B3J
Oxygen S88TT14065

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

10067-10078

Subventions

Organisme : British Heart Foundation
ID : RG/15/9/31534
Pays : United Kingdom
Organisme : British Heart Foundation
ID : RG/15/9/31534
Pays : United Kingdom

Informations de copyright

Copyright © 2020 the Author(s). Published by PNAS.

Déclaration de conflit d'intérêts

The authors declare no competing interest.

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Auteurs

Sarah L Richardson (SL)

Department of Physiology, Anatomy & Genetics, University of Oxford, OX1 3PT Oxford, England.

Alzbeta Hulikova (A)

Department of Physiology, Anatomy & Genetics, University of Oxford, OX1 3PT Oxford, England.

Melanie Proven (M)

Molecular Haematology Laboratory, Oxford University Hospitals National Health Service (NHS) Foundation Trust, John Radcliffe Hospital, OX3 9DS Oxford, England.

Ria Hipkiss (R)

Molecular Haematology Laboratory, Oxford University Hospitals National Health Service (NHS) Foundation Trust, John Radcliffe Hospital, OX3 9DS Oxford, England.

Magbor Akanni (M)

Haematology, Milton Keynes University Hospital, MK6 5LD Milton Keynes, England.

Noémi B A Roy (NBA)

Molecular Haematology Laboratory, Oxford University Hospitals National Health Service (NHS) Foundation Trust, John Radcliffe Hospital, OX3 9DS Oxford, England.
Weatherall Institute of Molecular Medicine & National Institute for Health Research (NIHR) Oxford Biomedical Research Center (BRC) Haematology Theme, University of Oxford, OX3 9DS Oxford, England.

Pawel Swietach (P)

Department of Physiology, Anatomy & Genetics, University of Oxford, OX1 3PT Oxford, England; pawel.swietach@dpag.ox.ac.uk.

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