Oleoylethanolamide, A Bioactive Lipid Amide, as A Promising Treatment Strategy for Coronavirus/COVID-19.


Journal

Archives of medical research
ISSN: 1873-5487
Titre abrégé: Arch Med Res
Pays: United States
ID NLM: 9312706

Informations de publication

Date de publication:
07 2020
Historique:
received: 05 04 2020
revised: 08 04 2020
accepted: 10 04 2020
pubmed: 25 4 2020
medline: 2 7 2020
entrez: 25 4 2020
Statut: ppublish

Résumé

The current outbreak of COVID-19 (coronavirus) has been identified by World Health Organization (WHO) as a global pandemic. With the emergence of the COVID-19 virus and considering the lack of effective pharmaceutical treatment for it, there is an urgent need to identify safe and effective drugs or potential adjuvant therapy in this regard. Bioactive lipids with an array of known health-promoting properties can be suggested as effective agents in alleviating acute respiratory stress induced by virus. The bioactive lipid amide, oleoylethanolamide (OEA), due to several distinctive homeostatic properties, including anti-inflammatory activities, modulation of immune response, and anti-oxidant effects can be considered as a novel potential pharmacological alternative for the management of COVID-19.

Identifiants

pubmed: 32327293
pii: S0188-4409(20)30475-6
doi: 10.1016/j.arcmed.2020.04.006
pmc: PMC7158763
pii:
doi:

Substances chimiques

Endocannabinoids 0
Oleic Acids 0
oleoylethanolamide 1HI5J9N8E6

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

464-467

Informations de copyright

Copyright © 2020 IMSS. Published by Elsevier Inc. All rights reserved.

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Auteurs

Samad Ghaffari (S)

Cardiovascular Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.

Neda Roshanravan (N)

Cardiovascular Research Center, Tabriz University of Medical Sciences, Tabriz, Iran. Electronic address: Neda.roshanravan10@gmail.com.

Helda Tutunchi (H)

Nutrition Research Center, Department of Clinical Nutrition, School of Nutrition and Food Sciences, Tabriz University of Medical Sciences, Tabriz, Iran.

Alireza Ostadrahimi (A)

Nutrition Research Center, Department of Clinical Nutrition, School of Nutrition and Food Sciences, Tabriz University of Medical Sciences, Tabriz, Iran.

Mahboub Pouraghaei (M)

Emergency Medicine Research Team, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran.

Behnam Kafil (B)

Nutrition Research Center, Department of Clinical Nutrition, School of Nutrition and Food Sciences, Tabriz University of Medical Sciences, Tabriz, Iran.

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Classifications MeSH