β-Adrenoceptors regulate matrix metalloproteinase expression in human urothelial cells under hydrostatic pressure.
Adrenergic beta-Agonists
/ pharmacology
Adrenergic beta-Antagonists
/ pharmacology
Epithelial Cells
/ drug effects
Gene Expression Regulation
Humans
Hydrostatic Pressure
Matrix Metalloproteinase 1
/ genetics
Matrix Metalloproteinase 2
/ genetics
Receptors, Adrenergic, beta-2
/ genetics
Receptors, Adrenergic, beta-3
/ genetics
Signal Transduction
/ drug effects
Tissue Inhibitor of Metalloproteinase-1
/ genetics
Urothelium
/ drug effects
human urothelial cells
matrix metalloproteinases
pathological hydrostatic pressure
tissue inhibitors of metalloproteinases
β-adrenoceptor
Journal
Neurourology and urodynamics
ISSN: 1520-6777
Titre abrégé: Neurourol Urodyn
Pays: United States
ID NLM: 8303326
Informations de publication
Date de publication:
06 2020
06 2020
Historique:
received:
01
12
2019
revised:
11
03
2020
accepted:
28
03
2020
pubmed:
25
4
2020
medline:
15
12
2020
entrez:
25
4
2020
Statut:
ppublish
Résumé
The bladder wall is constantly subjected to intravesical pressure during the filling and voiding cycles. An imbalance between matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs) under elevated intravesical pressure contributes to pathological changes in the bladder. To investigate the changes in human urothelial cells (HUCs) under elevated intravesical pressure, this study analyzed the effect of β-adrenoceptor signaling on the expression of MMPs and TIMPs in HUCs exposed to pathological hydrostatic pressure (HP) (70 cm H
Substances chimiques
Adrenergic beta-Agonists
0
Adrenergic beta-Antagonists
0
Receptors, Adrenergic, beta-2
0
Receptors, Adrenergic, beta-3
0
Tissue Inhibitor of Metalloproteinase-1
0
Matrix Metalloproteinase 2
EC 3.4.24.24
Matrix Metalloproteinase 1
EC 3.4.24.7
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
1292-1303Subventions
Organisme : National Natural Science Foundation of China
ID : 81770673
Pays : International
Organisme : National Natural Science Foundation of China
ID : 81702536
Pays : International
Organisme : National Natural Science Foundation of China
ID : 81800667
Pays : International
Organisme : National Natural Science Foundation of China
ID : 81873601
Pays : International
Organisme : Project of Science and Technology Department of Sichuan Province
ID : 2019JDR0144
Pays : International
Organisme : 1.3.5 Project for Disciplines of Excellence, West China Hospital, Sichuan University
ID : ZY2016104
Pays : International
Organisme : 1.3.5 Project for Disciplines of Excellence, West China Hospital, Sichuan University
ID : ZYGD18011
Pays : International
Informations de copyright
© 2020 Wiley Periodicals, Inc.
Références
Ghezzi CE, Marelli B, Muja N, Nazhat SN. Immediate production of a tubular dense collagen construct with bioinspired mechanical properties. Acta Biomater. 2012;8(5):1813-1825. https://doi.org/10.1016/j.actbio.2012.01.025
Natali AN, Audenino AL, Artibani W, Fontanella CG, Carniel EL, Zanetti EM. Bladder tissue biomechanical behavior: experimental tests and constitutive formulation. J Biomech. 2015;48(12):3088-3096. https://doi.org/10.1016/j.jbiomech.2015.07.021
Engebretson B, Mussett ZR, Sikavitsas VI. Tenocytic extract and mechanical stimulation in a tissue-engineered tendon construct increases cellular proliferation and ECM deposition. Biotechnol J. 2017;12(3):1600595. https://doi.org/10.1002/biot.201600595
Dodson RB, Morgan MR, Galambos C, Hunter KS, Abman SH. Chronic intrauterine pulmonary hypertension increases main pulmonary artery stiffness and adventitial remodeling in fetal sheep. Am J Physiol-Lung Cell Mol Physiol. 2014;307(11):L822-L828. https://doi.org/10.1152/ajplung.00256.2014
Vuichoud C, Loughlin KR. Benign prostatic hyperplasia: Epidemiology, economics and evaluation. Can J Urol. 2015;22:1-6.
Fusco F, Creta M, De Nunzio C, et al. Progressive bladder remodeling due to bladder outlet obstruction: a systematic review of morphological and molecular evidences in humans. BMC Urol. 2018;18(1):15. https://doi.org/10.1186/s12894-018-0329-4
Fry CH, Vahabi B. The role of the mucosa in normal and abnormal bladder function. Basic Clin Pharmacol Toxicol. 2016;119:57-62. https://doi.org/10.1111/bcpt.12626
Merrill L, Gonzalez EJ, Girard BM, Vizzard MA. Receptors, channels, and signalling in the urothelial sensory system in the bladder. Nat Rev Urol. 2016;13(4):193-204. https://doi.org/10.1038/nrurol.2016.13
Monson FC, Sun L, Wein AJ, Levin RM. Hyperplasia in the rabbit bladder urothelium following partial outlet obstruction. Autoradiographic evidence. Mol Cell Biochem. 1995;152(2):167-173. https://doi.org/10.1007/bf01076079
Arpino V, Brock M, Gill SE. The role of TIMPs in regulation of extracellular matrix proteolysis. Matrix Biol. 2015;44-46:247-254. https://doi.org/10.1016/j.matbio.2015.03.005
Szarvas T, vom Dorp F, Ergun S, Rubben H. Matrix metalloproteinases and their clinical relevance in urinary bladder cancer. Nat Rev Urol. 2011;8(5):241-254. https://doi.org/10.1038/nrurol.2011.44
Kapoor C, Vaidya S, Wadhwan V, Kaur G, Pathak A. Seesaw of matrix metalloproteinases (MMPs). J Cancer Res Ther. 2016;12(1):28-35. https://doi.org/10.4103/0973-1482.157337
Sumi T, Yoshida H, Hyun Y, et al. Expression of matrix metalloproteinases in human transitional cell carcinoma of the urinary bladder. Oncol Rep. 2003;10(2):345-349. https://doi.org/10.3892/or.10.2.345
Fingleton B. Matrix metalloproteinases as regulators of inflammatory processes. Biochimica et Biophysica Acta (BBA) - Mol Cell Res. 2017;1864(11):2036-2042. https://doi.org/10.1016/j.bbamcr.2017.05.010
Otsuka A, Shinbo H, Matsumoto R, Kurita Y, Ozono S. Expression and functional role of β-adrenoceptors in the human urinary bladder urothelium. Naunyn-Schmiedeberg's Arch Pharmacol. 2008;377(4):473-481. https://doi.org/10.1007/s00210-008-0274-y
Nomiya M, Yamaguchi O. A quantitative analysis of mRNA expression of α1 and β-adrenoceptor subtypes and their functional roles in human normal and obstructed bladders. J Urol. 2003;170(2):649-653. https://doi.org/10.1097/01.ju.0000067621.62736.7c
Rietz A, Spiers J. The relationship between the MMP system, adrenoceptors and phosphoprotein phosphatases. Br J Pharmacol. 2012;166(4):1225-1243. https://doi.org/10.1111/j.1476-5381.2012.01917.x
Wei TQ, Luo DY, Chen L, Wu T, Wang KJ. Cyclic hydrodynamic pressure induced proliferation of bladder smooth muscle cells via integrin alpha5 and FAK. Physiol Res. 2014;63(1):127-134.
Lai J, Ai J, Luo D, et al. β-Adrenoceptor signaling regulates proliferation and contraction of human bladder smooth muscle cells under pathological hydrostatic pressure. J Cell Biochem. 2019;120(10):17872-17886. https://doi.org/10.1002/jcb.29056
Buttyan R, Chen MW, Levin RM. Animal models of bladder outlet obstruction and molecular insights into the basis for the development of bladder dysfunction. Eur Urol. 1997;32:32-39.
Liang Z, Xin W, Qiang L, et al. Hydrostatic pressure and muscarinic receptors are involved in the release of inflammatory cytokines in human bladder smooth muscle cells. Neurourol Urodyn. 2017;36(5):1261-1269. https://doi.org/10.1002/nau.23104
Bu S, Zhu Y, Peng C, et al. Simulated physiological stretch-induced proliferation of human bladder smooth muscle cells is regulated by MMPs. Arch Biochem Biophys. 2014;564:197-202. https://doi.org/10.1016/j.abb.2014.09.012
Chen L, Wei TQ, Wang Y, Zhang J, Li H, Wang K-J. Simulated bladder pressure stimulates human bladder smooth muscle cell proliferation via the PI3K/SGK1 signaling pathway. J Urol. 2012;188(2):661-667. https://doi.org/10.1016/j.juro.2012.03.112
Chen L, Wu T, Wei TQ, et al. Skp2-mediated degradation of p27 regulates cell cycle progression in compressed human bladder smooth muscle cells. Kaohsiung J Med Sci. 2014;30(4):181-186. https://doi.org/10.1016/j.kjms.2013.07.002
Pittayapruek P, Meephansan J, Prapapan O, Komine M, Ohtsuki M. Role of matrix metalloproteinases in photoaging and photocarcinogenesis. Int J Mol Sci. 2016;17(6):868. https://doi.org/10.3390/ijms17060868
Xing Y, Shepherd N, Lan J, et al. MMPs/TIMPs imbalances in the peripheral blood and cerebrospinal fluid are associated with the pathogenesis of HIV-1-associated neurocognitive disorders. Brain Behav Immun. 2017;65:161-172. https://doi.org/10.1016/j.bbi.2017.04.024
Wieczorek E, Reszka E, Jablonowski Z, et al. Genetic polymorphisms in matrix metalloproteinases (MMPs) and tissue inhibitors of MPs (TIMPs), and bladder cancer susceptibility. BJU Int. 2013;112(8):1207-1214. https://doi.org/10.1111/bju.12230
Kim HH, Kim DH, Oh MH, Park KJ, Heo JH, Lee MW. Inhibition of matrix metalloproteinase-1 and type-I procollagen expression by phenolic compounds isolated from the leaves of Quercus mongolica in ultraviolet-irradiated human fibroblast cells. Arch Pharmacal Res. 2015;38(1):11-17. https://doi.org/10.1007/s12272-014-0329-1
Weremijewicz A, Matuszczak E, Sankiewicz A, et al. Matrix metalloproteinase-2 and its correlation with basal membrane components laminin-5 and collagen type IV in paediatric burn patients measured with surface plasmon resonance imaging (SPRI) biosensors. Burns. 2018;44(4):931-940. https://doi.org/10.1016/j.burns.2017.12.001
Yang L, Liu R, Wang X, He D. Imbalance between matrix metalloproteinase-1 (MMP-1) and tissue inhibitor of metalloproteinase-1 (TIMP-1) contributes to bladder compliance changes in rabbits with partial bladder outlet obstruction (PBOO). BJU Int. 2013;112(4):E391-E397. https://doi.org/10.1111/j.1464-410X.2012.11740.x
Peters CA, Freeman MR, Fernandez CA, Shepard J, Wiederschain DG, Moses MA. Dysregulated proteolytic balance as the basis of excess extracellular matrix in fibrotic disease. Am J Physiol-Regul, Integr Comp Physiol. 1997;272(6):R1960-R1965. https://doi.org/10.1152/ajpregu.1997.272.6.R1960
Backhaus BO, Kaefer M, Haberstroh KM, et al. Alterations in the molecular determinants of bladder compliance at hydrostatic pressures less than 40 cm. H2O. J Urol. 2002;168(6):2600-2604. https://doi.org/10.1097/01.ju.0000037531.90922.d4
Barbosa JABA, Reis ST, Nunes M, et al. The obstructed bladder: expression of collagen, matrix metalloproteinases, muscarinic receptors, and angiogenic and neurotrophic factors in patients with benign prostatic hyperplasia. Urology. 2017;106:167-172. https://doi.org/10.1016/j.urology.2017.05.010
Michel M. β-Adrenergic receptor subtypes in the urinary tract. In: Andersson K, Michel M, eds. Urinary tract. Handbook of experimental pharmacology. Berlin, Heidelberg: Springer; 2011:307-318.
Kurizaki Y, Ishizuka O, Imamura T, et al. Relationship between expression of β3-adrenoceptor mRNA in bladder mucosa and urodynamic findings in men with lower urinary tract symptoms. Neurourol Urodyn. 2013;32(1):88-91. https://doi.org/10.1002/nau.22278
Hopps E, Lo Presti R, Caimi G. Matrix metalloproteases in arterial hypertension and their trend after antihypertensive treatment. Kidney Blood Pressure Res. 2017;42(2):347-357. https://doi.org/10.1159/000477785
Kanayama H. Matrix metalloproteinases and bladder cancer. J Med Invest. 2001;48(1-2):31-43.