Synthesis, spectral properties and antimicrobial activity of a new cationic water-soluble pH-dependent poly(propylene imine) dendrimer modified with 1,8-naphthalimides.

1,8-naphthalimide antimicrobial activity, quaternary ammonium salts dendrimer fluorescence pH sensorpoly(propylene imine)

Journal

Luminescence : the journal of biological and chemical luminescence
ISSN: 1522-7243
Titre abrégé: Luminescence
Pays: England
ID NLM: 100889025

Informations de publication

Date de publication:
Sep 2020
Historique:
received: 21 12 2019
revised: 28 02 2020
accepted: 01 04 2020
pubmed: 26 4 2020
medline: 29 7 2021
entrez: 26 4 2020
Statut: ppublish

Résumé

A three-step synthesis was implemented to prepare a quaternary ammonium functionalized blue fluorescent poly(propylene imine) dendrimer modified with pyridinium salt of 4-acylamino-1,8-naphthalimide. The new cationic dendrimer absorbs in the ultraviolet light region and emits blue fluorescence. Its spectral characteristics in organic solvents and in an aqueous solution were studied. The influence of pH on the fluorescence intensity of the dendrimer was established with regard to its use as a pH sensor. The effect of hydroxyl ions on the absorption and fluorescence spectra in dry N,N-dimethylformamide was also investigated. The antimicrobial activity of the dendrimer was assessed against model pathogenic microorganisms in agar, liquid medium, and after its deposition on cotton fabric.

Identifiants

pubmed: 32333490
doi: 10.1002/bio.3809
doi:

Substances chimiques

Anti-Infective Agents 0
Dendrimers 0
Naphthalimides 0
Polypropylenes 0
poly(propyleneimine) 0
Water 059QF0KO0R

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

947-954

Subventions

Organisme : Ministry of Education and Science of Bulgaria
ID : Grant № DX 09/3 2016
Organisme : Ministry of Education and Science of Bulgaria
ID : DX 09/3 2016

Informations de copyright

© 2020 John Wiley & Sons, Ltd.

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Auteurs

Desislava Staneva (D)

University of Chemical Technology and Metallurgy, Sofia, Bulgaria.

Hristo Manov (H)

Faculty of Chemistry and Pharmacy, Sofia University 'St. Kliment Ohridski', Sofia, Bulgaria.

Stanislava Yordanova (S)

Faculty of Chemistry and Pharmacy, Sofia University 'St. Kliment Ohridski', Sofia, Bulgaria.

Evgenia Vasileva-Tonkova (E)

Bulgarian Academy of Sciences, The Stephan Angeloff Institute of Microbiology, Sofia, Bulgaria.

Stanimir Stoyanov (S)

Faculty of Chemistry and Pharmacy, Sofia University 'St. Kliment Ohridski', Sofia, Bulgaria.

Ivo Grabchev (I)

Faculty of Medicine, Sofia University 'St. Kliment Ohridski', Sofia, Bulgaria.

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