Total Atherosclerosis Burden of Baroreceptor-Resident Arteries Independently Predicts Blood Pressure Dipping in Patients With Ischemic Stroke.
Aged
Aorta, Thoracic
/ diagnostic imaging
Atherosclerosis
/ diagnosis
Blood Pressure Monitoring, Ambulatory
/ methods
Carotid Sinus
/ diagnostic imaging
Computed Tomography Angiography
/ methods
Correlation of Data
Female
Heart Disease Risk Factors
Humans
Hypotension
/ diagnosis
Ischemic Stroke
/ diagnosis
Male
Pressoreceptors
/ physiopathology
Severity of Illness Index
atherosclerosis
baroreceptor
baroreflex
blood pressure
carotid sinus
dipping
stroke
Journal
Hypertension (Dallas, Tex. : 1979)
ISSN: 1524-4563
Titre abrégé: Hypertension
Pays: United States
ID NLM: 7906255
Informations de publication
Date de publication:
06 2020
06 2020
Historique:
pubmed:
28
4
2020
medline:
10
4
2021
entrez:
28
4
2020
Statut:
ppublish
Résumé
Nighttime blood pressure (BP) generally dips by 10% to 20% of the daytime values, and abnormal BP dipping may affect vascular health independently of BP level. The regulation of BP dipping involves arterial baroreflex, whose receptors mainly reside in carotid sinuses and aortic arch. Atherosclerosis in these baroreceptor-resident arteries (BRAs) is frequent among patients with ischemic stroke (IS) and might impair their BP-regulating capacity. We aimed to examine associations between atherosclerosis of BRA and BP dipping in patients with IS. BP dipping ratio was measured by 24-hour ambulatory blood pressure monitoring on the sixth day after IS. With computed tomography angiography, atherosclerosis conditions in 10 segments of carotid sinuses and aortic arch were scored and summed as total atherosclerosis burden of BRA. Among the 245 patients with IS, 78.0% had atherosclerosis in BRA. The total AS burden of BRA was negatively correlated with systolic BP dipping ratio (
Identifiants
pubmed: 32336234
doi: 10.1161/HYPERTENSIONAHA.120.15036
pmc: PMC7682798
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
1505-1512Références
JAMA. 2006 Jun 28;295(24):2859-66
pubmed: 16804152
Arterioscler Thromb Vasc Biol. 2004 Jan;24(1):12-22
pubmed: 14604830
BMC Neurol. 2004 Jan 06;4:1
pubmed: 14706120
Exp Physiol. 2003 Nov;88(6):671-80
pubmed: 14603365
Am J Hypertens. 2004 Oct;17(10):977-80
pubmed: 15485763
Clin Exp Pharmacol Physiol. 2008 Sep;35(9):987-94
pubmed: 18565197
J Hypertens. 1996 Dec;14(12):1427-32
pubmed: 8986925
Circ Res. 1978 Feb;42(2):230-6
pubmed: 413669
Circ Res. 1980 Feb;46(2):237-44
pubmed: 7351041
Int J Cardiol. 2018 Jul 15;263:132-137
pubmed: 29754908
Stroke. 1993 Jan;24(1):35-41
pubmed: 7678184
Atherosclerosis. 2016 Aug;251:1-5
pubmed: 27214693
Stroke. 2005 Sep;36(9):1891-5
pubmed: 16100025
Hypertension. 2011 Jan;57(1):3-10
pubmed: 21079049
Int J Gen Med. 2018 Jun 22;11:241-254
pubmed: 29950885
Medicine (Baltimore). 2015 Mar;94(10):e604
pubmed: 25761180
J Hypertens. 2014 Jul;32(7):1359-66
pubmed: 24886823
Stroke. 2014 Jul;45(7):2160-236
pubmed: 24788967
Nat Rev Cardiol. 2013 Mar;10(3):143-55
pubmed: 23399972
Atherosclerosis. 2017 Dec;267:139-145
pubmed: 29128778
Hypertens Res. 2013 Mar;36(3):232-9
pubmed: 23076404
Hypertens Res. 2016 May;39(5):277-92
pubmed: 26657008
Korean Circ J. 2019 Sep;49(9):818-828
pubmed: 31456375
Hypertension. 2016 Apr;67(4):693-700
pubmed: 26902495
Hypertension. 2018 Mar;71(3):403-405
pubmed: 29295854
J Stroke Cerebrovasc Dis. 2019 Jun;28(6):1586-1596
pubmed: 30928215
Acta Neurol Scand. 2012 Aug;126(2):122-8
pubmed: 22077726