Chronotherapy for reduction of cardiovascular risk.

Cronoterapia para reducción de riesgo cardiovascular.
Antihypertensive Agents / therapeutic use Blood Pressure Blood Pressure Monitoring, Ambulatory Cardiovascular Diseases / diagnosis Chronotherapy Circadian Rhythm Heart Disease Risk Factors Humans Hypertension / diagnosis Prospective Studies Risk Factors
Ambulatory blood pressure monitoring Asleep blood pressure Cardiovascular risk Chronobiology Chronotherapy Cronobiología Cronoterapia Diabetes Diagnosis of hypertension Diagnóstico de hipertensión Enfermedad renal Kidney disease Monitorización ambulatoria de la presión arterial Presión arterial durante el sueño Profundidad de la presión arterial Riesgo cardiovascular Sleep-time relative blood pressure decline

Journal

Medicina clinica
ISSN: 1578-8989
Titre abrégé: Med Clin (Barc)
Pays: Spain
ID NLM: 0376377

Informations de publication

Date de publication:
26 06 2020
Historique:
received: 12 12 2019
revised: 25 02 2020
accepted: 26 02 2020
pubmed: 28 4 2020
medline: 15 5 2021
entrez: 28 4 2020
Statut: ppublish

Résumé

Numerous prospective studies establish that elevated asleep blood pressure (BP) constitutes a significant cardiovascular disease (CVD) risk factor, irrespective of daytime office BP measurements or awake and 24h BP measurements. Moreover, except for a small number of studies with flawed methodology, multiple clinical trials of high consistency document significantly better BP-lowering efficacy of hypertension medication and their combinations when ingested at bedtime compared to upon awakening as is customary. Additionally, recent trials conclude bedtime hypertension chronotherapy markedly reduces CVD risk not only in the general population, but also in more vulnerable patients of advanced age, with kidney disease, diabetes, or resistant hypertension. Collectively, these results call for a new definition of true arterial hypertension and its proper diagnosis and management.

Identifiants

DOI: 10.1016/j.medcli.2020.02.004 PMID: 32336474
pubmed: 32336474
pii: S0025-7753(20)30171-8
doi: 10.1016/j.medcli.2020.02.004
pii:
doi:

Substances chimiques

Antihypertensive Agents 0

Types de publication

Journal Article Review

Langues

eng spa

Sous-ensembles de citation

IM

Pagination

505-511

Informations de copyright

Copyright © 2020 Elsevier España, S.L.U. All rights reserved.

Auteurs

Ramón C Hermida (RC)

Laboratorio de Bioingeniería y Cronobiología, Atlantic Research Center for Information and Communication Technologies (atlanTTic), Universidad de Vigo, Vigo, España; Department of Biomedical Engineering, Cockrell School of Engineering, The University of Texas at Austin, Austin, Texas, Estados Unidos. Electronic address: rhermida@uvigo.es.

Ramón G Hermida-Ayala (RG)

Chief Parmacology Officer (CPO), Circadian Ambulatory Technology & Diagnostics (CAT&D), Santiago de Compostela, La Coruña, España.

Michael Smolensky (M)

Department of Biomedical Engineering, Cockrell School of Engineering, The University of Texas at Austin, Austin, Texas, Estados Unidos.

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Classifications MeSH

questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Utilisations thérapeutiques › Agents cardiovasculaires › Antihypertenseurs › Chronotherapy for reduction of cardiovascular risk.
questionsmedicales.fr › Phénomènes physiologiques respiratoires et circulatoires › Phénomènes physiologiques cardiovasculaires › Hémodynamique › Pression sanguine › Chronotherapy for reduction of cardiovascular risk.
questionsmedicales.fr › Diagnostic › Techniques et procédures diagnostiques › Monitorage physiologique › Surveillance électronique ambulatoire › Surveillance ambulatoire de la pression artérielle › Chronotherapy for reduction of cardiovascular risk.
questionsmedicales.fr › Maladies cardiovasculaires › Chronotherapy for reduction of cardiovascular risk.
questionsmedicales.fr › Thérapeutique › Chronothérapie › Chronotherapy for reduction of cardiovascular risk.
questionsmedicales.fr › Phénomènes physiologiques › Phénomènes chronobiologiques › Périodicité › Rythme circadien › Chronotherapy for reduction of cardiovascular risk.
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Statistiques comme sujet › Probabilité › Risque › Facteurs de risque › Facteurs de risque de maladie cardiaque › Chronotherapy for reduction of cardiovascular risk.
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Chronotherapy for reduction of cardiovascular risk.
questionsmedicales.fr › Maladies cardiovasculaires › Maladies vasculaires › Hypertension artérielle › Chronotherapy for reduction of cardiovascular risk.
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Caractéristiques des études épidémiologiques › Études épidémiologiques › Études de cohortes › Études prospectives › Chronotherapy for reduction of cardiovascular risk.
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Statistiques comme sujet › Probabilité › Risque › Facteurs de risque › Chronotherapy for reduction of cardiovascular risk.