Air Particulate Matter Induces Skin Barrier Dysfunction and Water Transport Alteration on a Reconstructed Human Epidermis Model.
Journal
The Journal of investigative dermatology
ISSN: 1523-1747
Titre abrégé: J Invest Dermatol
Pays: United States
ID NLM: 0426720
Informations de publication
Date de publication:
12 2020
12 2020
Historique:
received:
01
12
2018
revised:
24
03
2020
accepted:
31
03
2020
pubmed:
28
4
2020
medline:
2
4
2021
entrez:
28
4
2020
Statut:
ppublish
Résumé
Knowing the damage that particulate matter (PM) can cause in skin is important for tightly controlling the release of air pollutants and preventing more serious diseases. This study investigates if such alterations are present in reconstructed human epidermis exposed to coarse air PM. Exposure of reconstructed human epidermis to increasing concentrations (2.2, 8.9, and 17.9 μg/cm
Identifiants
pubmed: 32339540
pii: S0022-202X(20)31403-2
doi: 10.1016/j.jid.2020.03.971
pii:
doi:
Substances chimiques
Air Pollutants
0
Biomarkers
0
FLG protein, human
0
Filaggrin Proteins
0
Particulate Matter
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
2343-2352.e3Informations de copyright
Copyright © 2020 The Authors. Published by Elsevier Inc. All rights reserved.