May patients receiving 5-alpha-reductase inhibitors be in higher risk of COVID-19 complications?
5-alpha Reductase Inhibitors
/ adverse effects
Animals
Betacoronavirus
COVID-19
Coronavirus Infections
/ complications
Finasteride
/ adverse effects
Humans
Lung
/ drug effects
Male
Pandemics
Pneumonia, Viral
/ complications
Prognosis
Prostatic Hyperplasia
/ complications
Respiratory Mucosa
/ drug effects
SARS-CoV-2
Sex Factors
Journal
Medical hypotheses
ISSN: 1532-2777
Titre abrégé: Med Hypotheses
Pays: United States
ID NLM: 7505668
Informations de publication
Date de publication:
Jul 2020
Jul 2020
Historique:
received:
30
03
2020
accepted:
21
04
2020
pubmed:
29
4
2020
medline:
12
9
2020
entrez:
29
4
2020
Statut:
ppublish
Résumé
COVID-19 pandemic is a major challenge for global and national healthcare providers. Number of new cases is continuously increasing with an emerging trend showing worse prognosis in males in comparison to females. Based on this observation, our proposed hypothesis is that 5-alpha-reductase inhibitors, that are commonly used for BPH treatment, may be one of the factors contributing to poorer prognosis in males.
Identifiants
pubmed: 32344304
pii: 109751
pii: S0306-9877(20)30590-9
doi: 10.1016/j.mehy.2020.109751
pmc: PMC7175887
doi:
Substances chimiques
5-alpha Reductase Inhibitors
0
Finasteride
57GNO57U7G
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
109751Informations de copyright
© 2020 Published by Elsevier Ltd.
Déclaration de conflit d'intérêts
The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
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