Plasma copeptin levels in patients with multiple sclerosis.


Journal

Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia
ISSN: 1532-2653
Titre abrégé: J Clin Neurosci
Pays: Scotland
ID NLM: 9433352

Informations de publication

Date de publication:
Aug 2020
Historique:
received: 14 04 2020
accepted: 15 04 2020
pubmed: 30 4 2020
medline: 19 3 2021
entrez: 30 4 2020
Statut: ppublish

Résumé

We compared copeptin levels in relapsing-remitting multiple sclerosis (RRMS) patients with controls and investigated how plasma copeptin levels were changed with the disease period. Thirty patients with RRMS without a prior attack in the last twelve months, and 19 RRMS patients with a clinical acute attack and 30 healthy individuals were included into the study. Copeptin levels were significantly higher in all RRMS patient groups than healthy controls. Plasma copeptin levels were higher in patients in remission period compared with relapse period of 19 RRMS patients with an acute attack. We consider copeptin can be used as a potential biomarker for RRMS.

Identifiants

pubmed: 32345514
pii: S0967-5868(20)30348-9
doi: 10.1016/j.jocn.2020.04.095
pii:
doi:

Substances chimiques

Biomarkers 0
Glycopeptides 0
copeptins 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

143-146

Informations de copyright

Copyright © 2020 Elsevier Ltd. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Auteurs

Mesrure Koseoglu (M)

Department of Neurology, Bakirkoy Psychiatry and Neurology Research and Training Hospital, Istanbul, Turkey.

Serkan Ozben (S)

Department of Neurology, Antalya Training and Research Hospital, Antalya, Turkey. Electronic address: serkanozben@yahoo.com.

Gokcen Gozubatik-Celik (G)

Department of Neurology, Bakirkoy Psychiatry and Neurology Research and Training Hospital, Istanbul, Turkey.

Mesude Tutuncu (M)

Department of Neurology, Bakirkoy Psychiatry and Neurology Research and Training Hospital, Istanbul, Turkey.

Ertan Kucuksayan (E)

Department of Biochemistry, Medical Faculty, Akdeniz University, Antalya, Turkey.

Aysegul Hanikoğlu (A)

Department of Biochemistry, Medical Faculty, Akdeniz University, Antalya, Turkey.

Dilek Atakli (D)

Department of Neurology, Bakirkoy Psychiatry and Neurology Research and Training Hospital, Istanbul, Turkey.

Tomris Ozben (T)

Department of Biochemistry, Medical Faculty, Akdeniz University, Antalya, Turkey.

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Classifications MeSH