Screening and Treatment Outcomes in Adults and Children With Type 1 Diabetes and Asymptomatic Celiac Disease: The CD-DIET Study.
Adolescent
Adult
Asymptomatic Diseases
Autoantibodies
/ analysis
Biopsy
Blood Glucose
/ analysis
Blood Glucose Self-Monitoring
Canada
Celiac Disease
/ blood
Child
Diabetes Mellitus, Type 1
/ blood
Diet, Gluten-Free
Female
Humans
Male
Mass Screening
Middle Aged
Postprandial Period
Serologic Tests
Treatment Outcome
Young Adult
Journal
Diabetes care
ISSN: 1935-5548
Titre abrégé: Diabetes Care
Pays: United States
ID NLM: 7805975
Informations de publication
Date de publication:
07 2020
07 2020
Historique:
received:
30
09
2019
accepted:
25
03
2020
pubmed:
30
4
2020
medline:
16
3
2021
entrez:
30
4
2020
Statut:
ppublish
Résumé
To describe celiac disease (CD) screening rates and glycemic outcomes of a gluten-free diet (GFD) in patients with type 1 diabetes who are asymptomatic for CD. Asymptomatic patients (8-45 years) were screened for CD. Biopsy-confirmed CD participants were randomized to GFD or gluten-containing diet (GCD) to assess changes in HbA Adults had higher CD-seropositivity rates than children (6.8% [95% CI 4.9-8.2%, CD is frequently observed in asymptomatic patients with type 1 diabetes, and clinical vigilance is warranted with initiation of a GFD.
Identifiants
pubmed: 32345653
pii: dc19-1944
doi: 10.2337/dc19-1944
doi:
Substances chimiques
Autoantibodies
0
Blood Glucose
0
Banques de données
figshare
['10.2337/figshare.12041016']
ClinicalTrials.gov
['NCT01566110']
Types de publication
Journal Article
Multicenter Study
Randomized Controlled Trial
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
1553-1556Informations de copyright
© 2020 by the American Diabetes Association.