Eicosanoids in Nonalcoholic Fatty Liver Disease (NAFLD) Progression. Do Serum Eicosanoids Profile Correspond with Liver Eicosanoids Content during NAFLD Development and Progression?


Journal

Molecules (Basel, Switzerland)
ISSN: 1420-3049
Titre abrégé: Molecules
Pays: Switzerland
ID NLM: 100964009

Informations de publication

Date de publication:
27 Apr 2020
Historique:
received: 25 03 2020
revised: 22 04 2020
accepted: 23 04 2020
entrez: 1 5 2020
pubmed: 1 5 2020
medline: 9 2 2021
Statut: epublish

Résumé

Nonalcoholic fatty liver disease (NAFLD) is becoming a major public health problem worldwide. The study aimed to evaluate the concentration of eicosanoids in serum and liver tissue during steatosis progression and to assess whether eicosanoid change scores may predict liver tissue remodeling. Thirty six eight-week-old male Sprague Dawley rats were enrolled and sacrificed at different stages of NAFLD. Eicosanoid concentrations, namely lipoxin A

Identifiants

pubmed: 32349225
pii: molecules25092026
doi: 10.3390/molecules25092026
pmc: PMC7248881
pii:
doi:

Substances chimiques

10,17-dihydroxydocosa-4,7,11,13,15,19-hexaenoic acid 0
7,14-dihydroxydocosa-4,8,10,12,16,19-hexaenoic acid 0
Biomarkers 0
Eicosanoids 0
Hydroxyeicosatetraenoic Acids 0
Linoleic Acids 0
Lipoxins 0
lipoxin A4 0
resolvin D1 0
Docosahexaenoic Acids 25167-62-8
13-hydroxy-9,11-octadecadienoic acid 5204-88-6
Eicosapentaenoic Acid AAN7QOV9EA
5S,12R,18R-trihydroxy-6Z,8E,10E,14Z,16E-eicosapentaenoic acid GND3JH08JA
Dinoprostone K7Q1JQR04M

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : Narodowe Centrum Nauki
ID : 2016/21/N/NZ5/02584

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Auteurs

Dominika Maciejewska (D)

Department of Human Nutrition and Metabolomics, Pomeranian Medical University in Szczecin, 70-204 Szczecin, Poland.

Arleta Drozd (A)

Department of Human Nutrition and Metabolomics, Pomeranian Medical University in Szczecin, 70-204 Szczecin, Poland.

Karolina Skonieczna-Żydecka (K)

Department of Human Nutrition and Metabolomics, Pomeranian Medical University in Szczecin, 70-204 Szczecin, Poland.

Marta Skórka-Majewicz (M)

Department of Human Nutrition and Metabolomics, Pomeranian Medical University in Szczecin, 70-204 Szczecin, Poland.

Karolina Dec (K)

Department of Human Nutrition and Metabolomics, Pomeranian Medical University in Szczecin, 70-204 Szczecin, Poland.

Karolina Jakubczyk (K)

Department of Human Nutrition and Metabolomics, Pomeranian Medical University in Szczecin, 70-204 Szczecin, Poland.

Anna Pilutin (A)

Department of Histology and Embryology, Pomeranian Medical University in Szczecin, 70-204 Szczecin, Poland.

Ewa Stachowska (E)

Department of Human Nutrition and Metabolomics, Pomeranian Medical University in Szczecin, 70-204 Szczecin, Poland.

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Classifications MeSH