Improving effects of Epimedium flavonoids on the selected reproductive features in layer hens after forced molting.
Animals
Avian Proteins
/ metabolism
Chickens
/ metabolism
Epimedium
/ chemistry
Estrogens
/ metabolism
Fallopian Tubes
/ drug effects
Female
Flavonoids
/ administration & dosage
Molting
Ovarian Follicle
/ drug effects
RNA, Messenger
/ metabolism
Receptors, Estrogen
/ metabolism
Receptors, Progesterone
/ metabolism
Reproduction
/ drug effects
fallopian tube
forced molting
layer hen
total flavonoid of Epimedium
Journal
Poultry science
ISSN: 1525-3171
Titre abrégé: Poult Sci
Pays: England
ID NLM: 0401150
Informations de publication
Date de publication:
May 2020
May 2020
Historique:
received:
22
09
2019
revised:
10
12
2019
accepted:
11
12
2019
entrez:
4
5
2020
pubmed:
4
5
2020
medline:
18
11
2020
Statut:
ppublish
Résumé
In the present study, for the purpose of investigating the effects of the total flavonoids of Epimedium (TFE) in regard to preventing the development of atrophied oviducts and follicles induced by forced molting, 300-day-old Hy-Line Brown layer hens were divided into 3 study groups as follows: the control (CON) group was the normal group, without forced molting and TFE treatments; the TFE1 group was treated by adding a 1‰ TFE treatment after forced molting; and the TFE0 group was not treated by TFE after forced molting. During this study's experimental process, the egg production rates were recorded each day. In addition, the hens were randomly chosen to be weighed every 4 D and also randomly selected to be sacrificed every 7 D. Then, sample tissues of albumen-secreting part and uterus from the fallopian tube of the layer hens were collected for PCR and hematoxylin-eosin staining tests. The results showed that the body weights, number of follicles, and weights and sizes of the fallopian tube for the TFE1 and TFE0 groups were significantly reduced when compared with those of the control group on the 15th D of the experiment. Furthermore, at the end of study, it was found that the egg production rates, weights of the fallopian tube, and ovarian follicles of TFE1 had recovered to normal levels. At the same time, the serum estrogen and the expressions of the progesterone receptor and estrogen receptor mRNA in fallopian tube were higher than those observed for the TFE0 group. The results of this study provided valuable evidence that TFE could improve the development of atrophied oviducts and increase the egg laying rates, thereby making it a potential multicomponent natural drug for egg production in the future.
Identifiants
pubmed: 32359613
pii: S0032-5791(20)30070-5
doi: 10.1016/j.psj.2019.12.053
pmc: PMC7597462
pii:
doi:
Substances chimiques
Avian Proteins
0
Estrogens
0
Flavonoids
0
RNA, Messenger
0
Receptors, Estrogen
0
Receptors, Progesterone
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
2757-2765Informations de copyright
Copyright © 2020. Published by Elsevier Inc.
Références
Andrologia. 2017 Dec;49(10):
pubmed: 28370226
Br Poult Sci. 2019 Jun;60(3):187-194
pubmed: 30686025
Poult Sci. 2019 Dec 1;98(12):7022-7029
pubmed: 31309232
Vet World. 2019;12(2):277-287
pubmed: 31040571
Anat Histol Embryol. 2018 Oct;47(5):493-497
pubmed: 29862543
Poult Sci. 2019 Oct 1;98(10):4416-4425
pubmed: 31065721
J Endocrinol. 2000 Dec;167(3):363-9
pubmed: 11115763
Clin Chim Acta. 2019 Aug;495:646-651
pubmed: 29729232
Poult Sci. 2016 Nov 1;95(11):2576-2591
pubmed: 27143766
Zhongguo Ying Yong Sheng Li Xue Za Zhi. 2017 Feb 08;33(2):174-178
pubmed: 29931927
Ultrason Sonochem. 2008 Apr;15(4):376-385
pubmed: 17951093
J Ethnopharmacol. 2011 Apr 12;134(3):519-41
pubmed: 21215308
Cell Differ Dev. 1990 Jun;30(3):207-18
pubmed: 2207839
J Agric Food Chem. 2014 Dec 24;62(51):12346-59
pubmed: 25436390
Poult Sci. 2014 Jun;93(6):1337-43
pubmed: 24879683
BMC Mol Cell Biol. 2019 Apr 1;20(1):3
pubmed: 31041887
Toxicol Lett. 2014 Mar 3;225(2):264-74
pubmed: 24398026
Poult Sci. 2017 Jun 1;96(6):1925-1933
pubmed: 28339778
J Microsc Ultrastruct. 2019 Jan-Mar;7(1):9-13
pubmed: 31008051
Food Chem. 2017 Mar 1;218:152-158
pubmed: 27719892
Biochem Biophys Res Commun. 2016 Sep 16;478(2):999-1005
pubmed: 27526993
Domest Anim Endocrinol. 2017 Oct;61:1-10
pubmed: 28551483
Am J Reprod Immunol. 2019 Sep;82(3):e13159
pubmed: 31206849
Poult Sci. 2019 Dec 1;98(12):7041-7049
pubmed: 31399736
Phytother Res. 2014 Jan;28(1):88-97
pubmed: 23494828