Detection of runs of homozygosity in conserved and commercial pig breeds in Poland.
Landrace
Puławska
Złotnicka
pig
runs of homozygosity
Journal
Journal of animal breeding and genetics = Zeitschrift fur Tierzuchtung und Zuchtungsbiologie
ISSN: 1439-0388
Titre abrégé: J Anim Breed Genet
Pays: Germany
ID NLM: 100955807
Informations de publication
Date de publication:
Nov 2020
Nov 2020
Historique:
received:
30
10
2019
revised:
01
04
2020
accepted:
03
04
2020
pubmed:
4
5
2020
medline:
28
5
2021
entrez:
4
5
2020
Statut:
ppublish
Résumé
Runs of homozygosity (ROH) are continuous segments of the genome that arose as a result of inbreeding, resulting in the inheritance of identical haplotypes from both parents who shared a common ancestor. In the present study, we performed a detailed characterization and comparison of ROH in four pig breeds, including intensively selected Polish Landrace as well as native unselected animals of Puławska and two Złotnicka breeds (White and Spotted). We used a medium-density PorcineSNP60 BeadChip assay (Illumina) and cgaTOH software to detect ROH covering a minimum of 30 adjacent SNPs and maintaining a size over 1 Mb. By analysing ROH distribution and frequency across the genome, we also identified genomic regions with high ROH frequency (so-called "ROH hotspots"). The obtained results showed that the analysed conserved breeds were characterized by a higher ROH span and higher ROH-based inbreeding coefficients (F
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
571-580Subventions
Organisme : National Research and Development Center (Poland)
ID : BIOSTRATEG2/297267/14/NCBR/2016
Informations de copyright
© 2020 Wiley-VCH GmbH.
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