T Follicular Regulatory Cell Suppression of T Follicular Helper Cell Function Is Context-Dependent
Animals
B-Lymphocytes
/ immunology
CD40 Antigens
/ genetics
Cell Communication
Cells, Cultured
Germinal Center
/ immunology
Interleukin-4
/ metabolism
Interleukins
/ metabolism
Lymphocyte Activation
Mice
Mice, Inbred C57BL
Mice, Knockout
Signal Transduction
T-Lymphocytes, Helper-Inducer
/ immunology
T-Lymphocytes, Regulatory
/ immunology
B cell receptor
T follicular helper cell
T regulatory cell
antibody production
germinal center
Journal
Frontiers in immunology
ISSN: 1664-3224
Titre abrégé: Front Immunol
Pays: Switzerland
ID NLM: 101560960
Informations de publication
Date de publication:
2020
2020
Historique:
received:
02
01
2020
accepted:
20
03
2020
entrez:
5
5
2020
pubmed:
5
5
2020
medline:
30
3
2021
Statut:
epublish
Résumé
The production of antibody-secreting plasma cells and memory B cells requires the interaction of T follicular helper (Tfh) cells with B cells in the follicle and is modulated by T follicular regulatory (Tfr) cells. We compare the effects of Tfr cells in an
Identifiants
pubmed: 32362895
doi: 10.3389/fimmu.2020.00637
pmc: PMC7181357
doi:
Substances chimiques
CD40 Antigens
0
Interleukins
0
Interleukin-4
207137-56-2
interleukin-21
MKM3CA6LT1
Types de publication
Journal Article
Research Support, N.I.H., Intramural
Langues
eng
Sous-ensembles de citation
IM
Pagination
637Informations de copyright
Copyright © 2020 Lopez-Ocasio, Buszko, Blain, Wang and Shevach.
Références
Immunity. 2008 Jul 18;29(1):138-49
pubmed: 18599325
Autoimmunity. 2012 Aug;45(5):333-47
pubmed: 22390182
J Immunol. 2002 Feb 1;168(3):1473-8
pubmed: 11801691
Immunology. 2002 Jun;106(2):222-8
pubmed: 12047751
J Immunol. 2007 Oct 15;179(8):5099-108
pubmed: 17911595
Immunity. 2001 Jan;14(1):1-11
pubmed: 11163225
Immunity. 2014 Dec 18;41(6):1026-39
pubmed: 25526313
J Clin Invest. 2014 Dec;124(12):5191-204
pubmed: 25347469
J Exp Med. 2000 Dec 4;192(11):1553-62
pubmed: 11104798
Immunol Rev. 2012 May;247(1):52-63
pubmed: 22500831
J Clin Invest. 2004 Dec;114(11):1640-9
pubmed: 15578096
Immunology. 2017 Sep;152(1):25-35
pubmed: 28617936
J Immunol. 2009 Aug 1;183(3):1518-22
pubmed: 19570829
J Exp Med. 2018 Mar 5;215(3):815-825
pubmed: 29378778
J Immunol. 2011 Nov 1;187(9):4553-60
pubmed: 21984700
Nat Med. 2011 Jul 24;17(8):975-82
pubmed: 21785433
Nat Immunol. 2019 Oct;20(10):1360-1371
pubmed: 31477921
Nat Immunol. 2016 Dec;17(12):1436-1446
pubmed: 27695002
Methods Mol Biol. 2015;1291:151-60
pubmed: 25836309
Nat Med. 2011 Jul 24;17(8):983-8
pubmed: 21785430
J Immunol. 2018 Dec 15;201(12):3569-3579
pubmed: 30446568
ACS Synth Biol. 2016 Jul 15;5(7):774-80
pubmed: 27110723
Immunity. 2014 Dec 18;41(6):1013-25
pubmed: 25526312
Nat Immunol. 2013 Feb;14(2):152-61
pubmed: 23242415
J Exp Med. 2000 Dec 4;192(11):1545-52
pubmed: 11104797
Nature. 2014 May 29;509(7502):637-40
pubmed: 24805232
Elife. 2017 May 12;6:
pubmed: 28498098
Immunity. 2008 Jul 18;29(1):127-37
pubmed: 18602282