questionsmedicales.fr
Facteurs biologiques
Protéines et peptides de signalisation intercellulaire
Cytokines
Interleukines
Interleukine-4
Interleukine-4 : Questions médicales fréquentes
Diagnostic
5
Tests diagnostiques
Cytométrie en flux
Asthme
Maladies auto-immunes
Inflammation
Lymphocytes B
Symptômes
5
Réactions allergiques
Asthme
Symptômes respiratoires
Interleukine-4
Urticaire
Rhinite allergique
Système immunitaire
Lymphocytes T
Prévention
5
Prévention des maladies
Allergènes
Éducation allergologique
Symptômes allergiques
Vaccinations
Réponse immunitaire
Contrôle de l'environnement
Allergènes
Régimes alimentaires
Réponse immunitaire
Traitements
5
Anticorps monoclonaux
Dupilumab
Thérapies biologiques
Inflammation
Médicaments anti-inflammatoires
Corticostéroïdes
Biomarqueurs
Efficacité des traitements
Complications
5
Exacerbations d'asthme
Réactions allergiques
Infections
Réponse immunitaire
Maladies chroniques
Rhinite allergique
Qualité de vie
Symptômes chroniques
Facteurs de risque
5
Antécédents familiaux
Allergènes
Polluants
Allergènes environnementaux
Tabagisme
Réponses allergiques
Stress
Réponse immunitaire
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"@type": "Question",
"name": "Quels tests diagnostiques sont utilisés pour l'IL-4 ?",
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"@type": "Question",
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"name": "L'IL-4 peut-elle causer des symptômes respiratoires ?",
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"name": "Quels signes cliniques indiquent une activité d'IL-4 ?",
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{
"@type": "Question",
"name": "L'IL-4 est-elle liée à des symptômes cutanés ?",
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"text": "Oui, l'IL-4 est impliquée dans des affections cutanées comme l'eczéma."
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"@type": "Question",
"name": "Comment l'IL-4 affecte-t-elle le système immunitaire ?",
"position": 10,
"acceptedAnswer": {
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"text": "L'IL-4 modifie la réponse immunitaire en favorisant la différenciation des lymphocytes T en Th2."
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},
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"@type": "Question",
"name": "Comment prévenir les maladies liées à l'IL-4 ?",
"position": 11,
"acceptedAnswer": {
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"text": "Éviter les allergènes et adopter un mode de vie sain peut aider à prévenir les maladies liées à l'IL-4."
}
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{
"@type": "Question",
"name": "L'éducation allergologique aide-t-elle ?",
"position": 12,
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{
"@type": "Question",
"name": "Les vaccinations influencent-elles l'IL-4 ?",
"position": 13,
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"position": 14,
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}
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{
"@type": "Question",
"name": "Les régimes alimentaires affectent-ils l'IL-4 ?",
"position": 15,
"acceptedAnswer": {
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"text": "Une alimentation équilibrée peut influencer la réponse immunitaire et les niveaux d'IL-4."
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},
{
"@type": "Question",
"name": "Quels traitements ciblent l'IL-4 ?",
"position": 16,
"acceptedAnswer": {
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}
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{
"@type": "Question",
"name": "Comment l'IL-4 est-elle impliquée dans les thérapies ?",
"position": 17,
"acceptedAnswer": {
"@type": "Answer",
"text": "L'IL-4 est une cible pour des thérapies biologiques visant à réduire l'inflammation allergique."
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},
{
"@type": "Question",
"name": "L'immunothérapie peut-elle affecter l'IL-4 ?",
"position": 18,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, l'immunothérapie peut moduler les niveaux d'IL-4 et améliorer les symptômes allergiques."
}
},
{
"@type": "Question",
"name": "Quels médicaments réduisent l'IL-4 ?",
"position": 19,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des médicaments anti-inflammatoires et des corticostéroïdes peuvent réduire l'IL-4."
}
},
{
"@type": "Question",
"name": "L'IL-4 est-elle un biomarqueur pour le traitement ?",
"position": 20,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les niveaux d'IL-4 peuvent servir de biomarqueur pour évaluer l'efficacité des traitements."
}
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{
"@type": "Question",
"name": "Quelles complications sont liées à l'IL-4 ?",
"position": 21,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des complications incluent des exacerbations d'asthme et des réactions allergiques sévères."
}
},
{
"@type": "Question",
"name": "L'IL-4 peut-elle aggraver des maladies ?",
"position": 22,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, une surproduction d'IL-4 peut aggraver des maladies comme l'asthme et l'eczéma."
}
},
{
"@type": "Question",
"name": "Des infections sont-elles liées à l'IL-4 ?",
"position": 23,
"acceptedAnswer": {
"@type": "Answer",
"text": "Une réponse immunitaire déséquilibrée par l'IL-4 peut augmenter le risque d'infections."
}
},
{
"@type": "Question",
"name": "L'IL-4 est-elle impliquée dans des maladies chroniques ?",
"position": 24,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, l'IL-4 est impliquée dans des maladies chroniques comme la rhinite allergique et l'asthme."
}
},
{
"@type": "Question",
"name": "Comment l'IL-4 affecte-t-elle la qualité de vie ?",
"position": 25,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les maladies liées à l'IL-4 peuvent réduire la qualité de vie en provoquant des symptômes chroniques."
}
},
{
"@type": "Question",
"name": "Quels facteurs augmentent le risque d'IL-4 élevé ?",
"position": 26,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les antécédents familiaux d'allergies et l'exposition à des allergènes augmentent le risque."
}
},
{
"@type": "Question",
"name": "L'environnement joue-t-il un rôle dans l'IL-4 ?",
"position": 27,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, l'exposition à des polluants et des allergènes environnementaux peut augmenter l'IL-4."
}
},
{
"@type": "Question",
"name": "Le tabagisme influence-t-il l'IL-4 ?",
"position": 28,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, le tabagisme peut exacerber les réponses allergiques et augmenter les niveaux d'IL-4."
}
},
{
"@type": "Question",
"name": "Le stress affecte-t-il l'IL-4 ?",
"position": 29,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, le stress peut influencer la réponse immunitaire et augmenter les niveaux d'IL-4."
}
},
{
"@type": "Question",
"name": "L'alimentation influence-t-elle l'IL-4 ?",
"position": 30,
"acceptedAnswer": {
"@type": "Answer",
"text": "Une alimentation riche en allergènes peut augmenter les niveaux d'IL-4 et le risque d'allergies."
}
}
]
}
]
}
Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale
Validation scientifique effectuée le 19/12/2025
Contenu vérifié selon les dernières recommandations médicales
4 publications dans cette catégorie
Affiliations :
Institute of Pharmacy and Food Chemistry, University of Würzburg, DE-97074 Würzburg, Germany; Helmholtz Institute for RNA based Infection Research, Josef-Schneider-Straße 2, DE-97080 Würzburg, Germany.
Publications dans "Interleukine-4" :
4 publications dans cette catégorie
Affiliations :
Institute of Pharmacy and Food Chemistry, University of Würzburg, DE-97074 Würzburg, Germany. Electronic address: tessa.luehmann@uni-wuerzburg.de.
Publications dans "Interleukine-4" :
2 publications dans cette catégorie
Affiliations :
Department of Neurology, Focus Program Translational Neuroscience (FTN) and Immunotherapy (FZI), Rhine Main Neuroscience Network (rmn(2)), University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany.
Publications dans "Interleukine-4" :
2 publications dans cette catégorie
Affiliations :
Department of Neurology, Focus Program Translational Neuroscience (FTN) and Immunotherapy (FZI), Rhine Main Neuroscience Network (rmn(2)), University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany. Electronic address: tineke.vogelaar@unimedizin-mainz.de.
Publications dans "Interleukine-4" :
2 publications dans cette catégorie
Affiliations :
Lehrstuhl für Botanik I, Molekulare Pflanzenphysik und Biophysik, University of Würzburg, DE-97082 Würzburg, Germany.
Publications dans "Interleukine-4" :
2 publications dans cette catégorie
Affiliations :
Department of Neurosurgery, University of Pennsylvania, Philadelphia, PA, USA. Donalddetchou@gmail.com.
University of Pennsylvania Perelman School of Medicine, 3400 Civic Center Blvd, Philadelphia, PA, 19104, USA. Donalddetchou@gmail.com.
Publications dans "Interleukine-4" :
2 publications dans cette catégorie
Affiliations :
Department of Neurosurgery, New York University Grossman School of Medicine, New York City, NYC, USA.
Publications dans "Interleukine-4" :
2 publications dans cette catégorie
Affiliations :
Departments of Pediatrics, College of Medicine, Najran University, Najran, Saudi Arabia.
Publications dans "Interleukine-4" :
2 publications dans cette catégorie
Affiliations :
Departments of Pediatrics, College of Medicine, Najran University, Najran, Saudi Arabia.
Publications dans "Interleukine-4" :
2 publications dans cette catégorie
Affiliations :
Department of Family and Community Medicine, College of Medicine, King Khalid University, Abha, Saudi Arabia.
Publications dans "Interleukine-4" :
2 publications dans cette catégorie
Affiliations :
Department of Microbiology, Zagazig University, Zagazig, Egypt.
Publications dans "Interleukine-4" :
2 publications dans cette catégorie
Affiliations :
Institute of Pharmacy and Food Chemistry, University of Würzburg, Am Hubland, 97074 Würzburg, Germany.
Publications dans "Interleukine-4" :
2 publications dans cette catégorie
Affiliations :
Institute of Pharmacy and Food Chemistry, University of Würzburg, Am Hubland, 97074 Würzburg, Germany.
Publications dans "Interleukine-4" :
2 publications dans cette catégorie
Affiliations :
Institute of Pharmacy and Food Chemistry, University of Würzburg, Am Hubland, 97074 Würzburg, Germany.
Publications dans "Interleukine-4" :
2 publications dans cette catégorie
Affiliations :
School of Biomedical Engineering, Sciences and Health Systems, Drexel University, Philadelphia, PA, USA. Electronic address: kls35@drexel.edu.
Publications dans "Interleukine-4" :
2 publications dans cette catégorie
Affiliations :
Department of Biotechnology and Laboratory Science in Medicine, National Yang-Ming University, Taipei, Taiwan.
Program in Molecular Medicine, National Yang-Ming University and Academia Sinica, Taipei, Taiwan.
Publications dans "Interleukine-4" :
2 publications dans cette catégorie
Affiliations :
Department of Biotechnology and Laboratory Science in Medicine, National Yang-Ming University, Taipei, Taiwan.
Program in Molecular Medicine, National Yang-Ming University and Academia Sinica, Taipei, Taiwan.
Publications dans "Interleukine-4" :
2 publications dans cette catégorie
Affiliations :
Department of Nursing, College of Nursing, Hungkuang University, Taichung, Taiwan.
Publications dans "Interleukine-4" :
2 publications dans cette catégorie
Affiliations :
Institute of Infectious Disease and Molecular Medicine, International Center for Genetic and Biotechnology Cape Town Component & University of Cape Town, Cape Town, South Africa.
Publications dans "Interleukine-4" :
1 publication dans cette catégorie
Affiliations :
Department of Neurology, Focus Program Translational Neuroscience (FTN) and Immunotherapy (FZI), Rhine Main Neuroscience Network (rmn(2)), University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany.
Publications dans "Interleukine-4" :
Glioblastoma multiforme (GBM) is one of the most aggressive and deadly forms of brain cancer, which has a very complex tumor microenvironment (TME) promoting tumor growth, immune evasion, and resistan...
In this review, the author highlights the role of IL4 in mitigating all the "hallmarks" of cancer growth and resistance to current immunotherapy, providing a framework for its role in GBM as well as g...
Immune thrombocytopenia (ITP) is an autoimmune disease characterized by the breakdown of immune tolerance. Impairment of the cellular immunity is primarily evaluated by the levels of the cytokines whi...
Serum IL-4 and IL-6 may have a role in the pathogenesis of primary ITP. IL-4 seems to be a good predictor to treatment response....
• There is a delicate balance of specific cytokine levels in immune thrombocytopenia, which has an important role in the immune system and is known to be deregulated in autoimmune diseases. changes in...
• We found that IL4 seems to be a good predictor to treatment response and it was a very interesting observation in our study, and to the best of our knowledge, there is no published data about this f...
Endometriosis is a complex gynaecological disorder that contributes to infertility, dysmenorrhea, dyspareunia, and other chronic issues. It is a multifactorial disease involving genetic, hormonal, imm...
was to analyse the polymorphisms in Interleukin 4, Interleukin 18, FCRL3 and sPLA2IIa genes to identify any significant association with the risk of endometriosis....
This study evaluated the polymorphism of -590 C/T in interleukin- 4(IL-4) gene, C607A in Interleukin - 18(IL-18) gene, -169T > C in FCRL3 gene and 763 C > G in sPLA2IIa gene in women with endometriosi...
Interleukin - 18 and FCRL3 gene polymorphisms of endometriotic tissue and blood samples of endometriosis (cases) showed significantly associated (OR = 4.88 [95% CI = 2.31-10.30], P > 0.0001) and (OR =...
The present study suggests that the IL-18 and FCRL3 gene polymorphisms are associated with a higher risk for endometriosis, which delivers valuable knowledge of endometriosis's pathogenesis. However, ...
Interleukin-4 (IL-4) is implicated in the progression of tuberculosis (TB); however, these results remain controversial....
This meta-analysis examined the relationship between IL and 4 polymorphisms (-589C/T, +4221C > A, and -33C/T) and the risk of TB....
A retrospective database analysis was conducted using the CNKI and PubMed databases. Using fixed- and random-effects models, we calculated the combined odds ratios (ORs) and 95% confidence intervals (...
We identified 14 articles related to this topic, and theresultsshowed that the IL-4 -589C/T polymorphism didnotinfluencethe risk of TB. However,in subgroupanalyses we found that the IL-4 -589C/T polym...
This meta-analysis showed that the IL-4 -589C/T polymorphism was associated with TB risk in Caucasian populations, and the IL-4 + 4221C > A polymorphism is associated with TB risk....
This study aimed to investigate the geospatial distribution of normal reference values of Interleukin 4 (IL-4) in healthy Chinese adults and to provide a basis for the development of standard referenc...
Immunoassays, which use antigen-antibody reactions, are the primary techniques used to selectively quantify specific disease markers in blood. Conventional immunoassays, such as the microplate-based e...
Despite the inherent regenerative ability of bone, large bone defect regeneration remains a major clinical challenge for orthopedic surgery. Therapeutic strategies medicated by M2 phenotypic macrophag...
The MTT assay, live and dead staining, and phalloidin/DAPI dual staining were used to evaluate biocompatibility in vitro. H&E staining was used to evaluate biocompatibility in vivo. Inflammatory macro...
The bioactive MDs-IL4 scaffold showed good cytocompatibility in RAW 264.7 macrophages and hBMSCs. The results confirmed that the bioactive MDs-IL4 scaffold could reduce inflammatory phenotypic macroph...
Our results demonstrate that the bioactive MDs-IL4 scaffold could be used as novel carrier system for other pro-osteogenic molecules, thus having potential applications in bone tissue regeneration....
Respiratory virus infections are the main causes of pediatric diseases. Human metapneumovirus (hMPV) is an enveloped RNA virus similar to severe acute respiratory syndrome coronavirus type 2, both of ...
Little is known about the changes and mechanisms of intestinal flora in primary immune thrombocytopenia (ITP) patients....
To explore the structural and functional differences of intestinal flora between ITP patients and healthy controls, and clarify the correlation between intestinal flora and Th1/Th2 imbalance....
Feces from ITP patients and healthy controls were studied by 16S rRNA and metagenomic techniques at phylum, genus, species or functional levels. Blood samples were collected for the detection of inter...
The following changes in ITP patients were found: a decrease of Bacteroidetes phylum, an increase of Proteobacteria phylum and alterations of ten genera and 1045 species. IL-2 and IL-4 were significan...
The mechanism underlying functional and structural changes of intestinal flora in ITP patients may be related to inflammation and immunity, providing possibilities of probiotics or fecal transplants f...