Medical treatment options for COVID-19.
Adenosine Monophosphate
/ administration & dosage
Administration, Intravenous
Alanine
/ administration & dosage
Amides
/ pharmacology
Antibodies, Monoclonal, Humanized
/ pharmacology
Antiviral Agents
/ administration & dosage
Betacoronavirus
/ drug effects
COVID-19
Chloroquine
/ adverse effects
Clinical Trials as Topic
Coronavirus Infections
/ drug therapy
Cytochrome P-450 CYP3A Inhibitors
/ pharmacology
Granulocyte-Macrophage Colony-Stimulating Factor
/ administration & dosage
Humans
Immunologic Factors
/ therapeutic use
Lopinavir
/ pharmacology
Pandemics
Pneumonia, Viral
/ drug therapy
Pyrazines
/ pharmacology
RNA, Viral
/ drug effects
Recombinant Proteins
/ administration & dosage
SARS-CoV-2
COVID-19
SARS-CoV-2
antiviral drugs
immunomodulators
treatment
Journal
European heart journal. Acute cardiovascular care
ISSN: 2048-8734
Titre abrégé: Eur Heart J Acute Cardiovasc Care
Pays: England
ID NLM: 101591369
Informations de publication
Date de publication:
Apr 2020
Apr 2020
Historique:
pubmed:
5
5
2020
medline:
17
6
2020
entrez:
5
5
2020
Statut:
ppublish
Résumé
Therapeutic options for coronavirus disease 2019 are desperately needed to respond to the ongoing severe acute respiratory syndrome coronavirus 2 pandemic. Both antiviral drugs and immunomodulators might have their place in the management of coronavirus disease 2019. Unfortunately, no drugs have been approved yet to treat infections with human coronaviruses. As it will take years to develop new therapies for severe acute respiratory syndrome coronavirus 2, the current focus is on the repurposing of drugs that have been approved or are in development for other conditions. Several clinical trials have already been conducted or are currently ongoing to evaluate the efficacy of such drugs. Here, we discuss the potential of these therapies for the treatment of coronavirus disease 2019.
Identifiants
pubmed: 32363880
doi: 10.1177/2048872620922790
pmc: PMC7235633
doi:
Substances chimiques
Amides
0
Antibodies, Monoclonal, Humanized
0
Antiviral Agents
0
Cytochrome P-450 CYP3A Inhibitors
0
Immunologic Factors
0
Pyrazines
0
RNA, Viral
0
Recombinant Proteins
0
Lopinavir
2494G1JF75
remdesivir
3QKI37EEHE
Adenosine Monophosphate
415SHH325A
sargramostim
5TAA004E22
Granulocyte-Macrophage Colony-Stimulating Factor
83869-56-1
Chloroquine
886U3H6UFF
favipiravir
EW5GL2X7E0
tocilizumab
I031V2H011
Alanine
OF5P57N2ZX
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
209-214Références
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