Quantitative structure activity relationship and molecular simulations for the exploration of natural potent VEGFR-2 inhibitors: an

Ligands Molecular Docking Simulation Molecular Dynamics Simulation Molecular Structure Quantitative Structure-Activity Relationship Vascular Endothelial Growth Factor Receptor-2 / antagonists & inhibitors
Angiogenesis VEGFR-2 molecular dynamics pharmacophore modeling reactivity

Journal

Journal of biomolecular structure & dynamics
ISSN: 1538-0254
Titre abrégé: J Biomol Struct Dyn
Pays: England
ID NLM: 8404176

Informations de publication

Date de publication:
May 2021
Historique:
pubmed: 5 5 2020
medline: 3 7 2021
entrez: 5 5 2020
Statut: ppublish

Résumé

VEGFR-2 has recently become an eye-catching molecular target for the novel therapeutic designs against cancer for its well known role in persuading angiogenesis in tumor cells. The current study set sights on the exploration of novel potent natural compound targeting VEGFR-2

Identifiants

DOI: 10.1080/07391102.2020.1754916 PMID: 32363995
pubmed: 32363995
doi: 10.1080/07391102.2020.1754916
doi:

Substances chimiques

Ligands 0
Vascular Endothelial Growth Factor Receptor-2 EC 2.7.10.1

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

2806-2823

Auteurs

Neha Sharma (N)

Department of Bioengineering, Integral University, Lucknow, India.

Mala Sharma (M)

Department of Biosciences, Integral University, Lucknow, India.

Qazi Inamur Rahman (QI)

Department of Chemistry, Integral University, Lucknow, India.

Salman Akhtar (S)

Department of Bioengineering, Integral University, Lucknow, India.
Novel Global Community Educational Foundation, Hebersham, Australia.

Mohd Muddassir (M)

Department of Chemistry, College of Sciences, King Saud University, Riyadh, Kingdom of Saudi Arabia.

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Classifications MeSH

questionsmedicales.fr › Actions chimiques et utilisations › Utilisations spécialisées de produits chimiques › Produits chimiques de laboratoire › Ligands › Quantitative structure activity relationship...
questionsmedicales.fr › Sciences de l'information › Méthodologies informatiques › Simulation numérique › Simulation de docking moléculaire › Quantitative structure activity relationship...
questionsmedicales.fr › Sciences de l'information › Méthodologies informatiques › Simulation numérique › Simulation de dynamique moléculaire › Quantitative structure activity relationship...
questionsmedicales.fr › Phénomènes chimiques › Structure moléculaire › Quantitative structure activity relationship...
questionsmedicales.fr › Phénomènes physiologiques › Phénomènes pharmacologiques et toxicologiques › Phénomènes pharmacologiques › Relation structure-activité › Relation quantitative structure-activité › Quantitative structure activity relationship...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Récepteurs de surface cellulaire › Récepteurs peptidiques › Récepteur facteur croissance › Récepteurs aux facteurs de croissance endothéliale vasculaire › Récepteur-2 au facteur croissance endothéliale vasculaire › Quantitative structure activity relationship...