Trifluoperazine an Antipsychotic Drug and Inhibitor of Mitochondrial Permeability Transition Protects Cytarabine and Ifosfamide-Induced Neurotoxicity.
Animals
Antineoplastic Agents
/ toxicity
Brain
/ cytology
Cells, Cultured
Cytarabine
/ toxicity
Disease Models, Animal
Humans
Ifosfamide
/ toxicity
Lipid Peroxidation
/ drug effects
Membrane Potential, Mitochondrial
/ drug effects
Mitochondria
/ drug effects
Neurons
/ cytology
Neuroprotective Agents
/ pharmacology
Neurotoxicity Syndromes
/ etiology
Oxidative Stress
/ drug effects
Primary Cell Culture
Rats
Rats, Wistar
Reactive Oxygen Species
/ metabolism
Trifluoperazine
/ pharmacology
Journal
Drug research
ISSN: 2194-9387
Titre abrégé: Drug Res (Stuttg)
Pays: Germany
ID NLM: 101602406
Informations de publication
Date de publication:
Jun 2020
Jun 2020
Historique:
pubmed:
5
5
2020
medline:
9
3
2021
entrez:
5
5
2020
Statut:
ppublish
Résumé
The link between Ca
Substances chimiques
Antineoplastic Agents
0
Neuroprotective Agents
0
Reactive Oxygen Species
0
Cytarabine
04079A1RDZ
Trifluoperazine
214IZI85K3
Ifosfamide
UM20QQM95Y
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
265-272Informations de copyright
© Georg Thieme Verlag KG Stuttgart · New York.
Déclaration de conflit d'intérêts
The authors declare that they have no conflict of interest.