Evaluation of the Automated Indirect Immunofluorescence Test for Antinuclear Antibodies.
ANA
EuroPattern
automation
indirect immunofluorescence method
Journal
Annals of clinical and laboratory science
ISSN: 1550-8080
Titre abrégé: Ann Clin Lab Sci
Pays: United States
ID NLM: 0410247
Informations de publication
Date de publication:
Mar 2020
Mar 2020
Historique:
entrez:
6
5
2020
pubmed:
6
5
2020
medline:
4
2
2021
Statut:
ppublish
Résumé
The performance of the automated indirect immunofluorescence system was compared with the manual method for detection of antinuclear antibodies (ANA) from 354 clinical serum samples. We compared the results (negative or positive), ANA patterns, and titers for the two methods. The coincidence rates for ANA positive and negative samples were 93.4% and 98.7%, respectively. The coincidence rates for single patterns, mixed patterns, and the final titers were 85.1%, 87.6%, and 87.6%, respectively. The homogeneous, speckled, cytoplasmic, centromere, multiple nuclear dots, and nucleolar pattern coincidence rates were 79.3%, 83.0%, 87.8%, 72.7%, 50%, and 56.3%, respectively. The automated indirect immunofluorescence system had acceptable accuracy for detection of ANA.
Substances chimiques
Antibodies, Antinuclear
0
Autoantibodies
0
Types de publication
Evaluation Study
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
282-286Informations de copyright
© 2020 by the Association of Clinical Scientists, Inc.