One-Step Synthesis of Polypyrrole-Coated Gold Nanoparticles for Use as a Photothermally Active Nano-System.
Cell Death
Chlorides
/ chemistry
Coated Materials, Biocompatible
/ chemistry
Electric Conductivity
Gold
/ chemistry
Gold Compounds
/ chemistry
Hep G2 Cells
Humans
Light
Metal Nanoparticles
/ chemistry
Particle Size
Polymers
/ chemical synthesis
Pyrroles
/ chemical synthesis
Spectrophotometry, Ultraviolet
Static Electricity
Temperature
AuPpy NPs
gold nanoparticles
photothermal activity
polypyrrole
ultra-fast synthesis
Journal
International journal of nanomedicine
ISSN: 1178-2013
Titre abrégé: Int J Nanomedicine
Pays: New Zealand
ID NLM: 101263847
Informations de publication
Date de publication:
2020
2020
Historique:
received:
16
02
2020
accepted:
01
04
2020
entrez:
6
5
2020
pubmed:
6
5
2020
medline:
3
7
2020
Statut:
epublish
Résumé
This paper introduces a simple one-step and ultra-fast method for synthesis of highly photothermally active polypyrrole-coated gold nanoparticles. The synthesis process is so simple that the reaction is very fast without the need for any additives or complicated steps. Polypyrrole-coated gold nanoparticles (AuPpy NPs) were synthesized by reacting chloroauric acid (HAuCl The synthesized AuPpy NPs showed a peak characteristic for gold nanoparticles (530-600 nm, molar ratio dependent) and a wide absorption band along the visible-NIR region with intensity about triple or even quadruple that of polypyrrole synthesized by the conventional FeCl This method simply and successfully synthesized AuPpy NPs nanoparticles that represent a safe alternative photothermally active multifunctional tool instead of highly toxic and non-biodegradable gold nanorods.
Identifiants
pubmed: 32368043
doi: 10.2147/IJN.S250042
pii: 250042
pmc: PMC7173958
doi:
Substances chimiques
Chlorides
0
Coated Materials, Biocompatible
0
Gold Compounds
0
Polymers
0
Pyrroles
0
polypyrrole
30604-81-0
Gold
7440-57-5
gold tetrachloride, acid
8H372EGX3V
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
2605-2615Informations de copyright
© 2020 Fadel et al.
Déclaration de conflit d'intérêts
The authors declare no conflicts of interest in this work. This work is supported by a Cairo University project 2016 entitled: “Nano-systems in topical photodynamic therapy and photodynamic diagnosis: preparation, characterization and clinical evaluation”.
Références
Nanoscale Res Lett. 2016 Dec;11(1):230
pubmed: 27119158
Nanomedicine (Lond). 2015 Jan;10(1):1-3
pubmed: 25597770
J R Soc Interface. 2006 Dec 22;3(11):741-52
pubmed: 17015302
J Control Release. 2016 Sep 28;238:311-312
pubmed: 27397489
J Immunol Methods. 1983 Dec 16;65(1-2):55-63
pubmed: 6606682
Opt Express. 2011 May 9;19(10):9607-16
pubmed: 21643219
Pharmacol Res. 2019 May;143:178-185
pubmed: 30611856
Nanomaterials (Basel). 2018 Nov 15;8(11):
pubmed: 30445694
Ther Deliv. 2013 Mar;4(3):307-13
pubmed: 23442078
ACS Nano. 2015 Jul 28;9(7):7052-71
pubmed: 26147899
Lasers Med Sci. 2017 Sep;32(7):1469-1477
pubmed: 28674789
Drug Dev Ind Pharm. 2019 Jun;45(6):937-945
pubmed: 30734589
Neural Regen Res. 2018 Aug;13(8):1455-1464
pubmed: 30106059
Arterioscler Thromb Vasc Biol. 1999 Mar;19(3):704-12
pubmed: 10073977
Dalton Trans. 2014 Jun 21;43(23):8620-32
pubmed: 24760299
Sci Rep. 2018 Mar 15;8(1):4589
pubmed: 29545580