Toronto aortic stenosis quality of life questionnaire (TASQ): validation in TAVI patients.


Journal

BMC cardiovascular disorders
ISSN: 1471-2261
Titre abrégé: BMC Cardiovasc Disord
Pays: England
ID NLM: 100968539

Informations de publication

Date de publication:
05 05 2020
Historique:
received: 20 11 2019
accepted: 12 04 2020
entrez: 7 5 2020
pubmed: 7 5 2020
medline: 2 12 2020
Statut: epublish

Résumé

Aortic stenosis (AS) is a common cardiac condition whose prevalence increases with age. The symptom burden associated with severe aortic stenosis (AS) can introduce significant lifestyle disruptions and if left untreated can lead to a poor prognosis. Quality of life (QoL) is an important consideration in these patients. The TASQ is a QoL tool that was developed for aortic stenosis patients. We evaluated the psychometric properties of this specific questionnaire in patients who underwent transcatheter aortic valve implantation (TAVI), which is a therapeutic option for patients with severe aortic stenosis (AS). The properties of the TASQ in measuring QoL were evaluated in AS patients undergoing TAVI. Patients presenting for the TAVI procedure (N = 62) were evaluated pre-TAVI, at discharge, 1-month, and 3-month follow-ups. Demographic information as well as caregiver status, and daily activities were recorded. In addition to the TASQ, they completed the KCCQ (Kansas City Cardiomyopathy Questionnaire) and the IIRS (Illness Intrusiveness Rating Scale). The TASQ is a 16-item self-administered questionnaire that assesses AS-specific QoL across five domains: physical symptoms; physical limitations; emotional impact; social limitations, and health expectations. TASQ subscales are internally consistent (α = 0.74-0.96) and showed significant improvements from baseline across assessments (p < 0.001). Construct validity evidence was demonstrated by correlations consistent with theoretically derived hypotheses across time points. The TASQ is a brief measure of AS-specific QoL that is sensitive to change in patients undergoing TAVI. Items on the TASQ capture important QoL concerns reported by AS patients, suggesting this is a measure of relevant and meaningful outcomes for this patient population. Detection of early improvements in QoL by the TASQ is promising, with important implications for the evaluation of procedural outcomes in this population.

Sections du résumé

BACKGROUND
Aortic stenosis (AS) is a common cardiac condition whose prevalence increases with age. The symptom burden associated with severe aortic stenosis (AS) can introduce significant lifestyle disruptions and if left untreated can lead to a poor prognosis. Quality of life (QoL) is an important consideration in these patients. The TASQ is a QoL tool that was developed for aortic stenosis patients. We evaluated the psychometric properties of this specific questionnaire in patients who underwent transcatheter aortic valve implantation (TAVI), which is a therapeutic option for patients with severe aortic stenosis (AS).
METHODS
The properties of the TASQ in measuring QoL were evaluated in AS patients undergoing TAVI. Patients presenting for the TAVI procedure (N = 62) were evaluated pre-TAVI, at discharge, 1-month, and 3-month follow-ups. Demographic information as well as caregiver status, and daily activities were recorded. In addition to the TASQ, they completed the KCCQ (Kansas City Cardiomyopathy Questionnaire) and the IIRS (Illness Intrusiveness Rating Scale).
RESULTS
The TASQ is a 16-item self-administered questionnaire that assesses AS-specific QoL across five domains: physical symptoms; physical limitations; emotional impact; social limitations, and health expectations. TASQ subscales are internally consistent (α = 0.74-0.96) and showed significant improvements from baseline across assessments (p < 0.001). Construct validity evidence was demonstrated by correlations consistent with theoretically derived hypotheses across time points.
CONCLUSIONS
The TASQ is a brief measure of AS-specific QoL that is sensitive to change in patients undergoing TAVI. Items on the TASQ capture important QoL concerns reported by AS patients, suggesting this is a measure of relevant and meaningful outcomes for this patient population. Detection of early improvements in QoL by the TASQ is promising, with important implications for the evaluation of procedural outcomes in this population.

Identifiants

pubmed: 32370791
doi: 10.1186/s12872-020-01477-2
pii: 10.1186/s12872-020-01477-2
pmc: PMC7201733
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't Validation Study

Langues

eng

Sous-ensembles de citation

IM

Pagination

209

Subventions

Organisme : Edwards Lifesciences
ID : 410007511
Pays : International

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Auteurs

Rima Styra (R)

Center for Mental Health, University Health Network, Toronto, Ontario, Canada. Rima.Styra@uhn.ca.

Michelle Dimas (M)

Center for Mental Health, University Health Network, Toronto, Ontario, Canada.

Kathy Svitak (K)

Peter Munk Cardiac Center, University Health Network, Toronto, Ontario, Canada.

Mamta Kapoor (M)

Center for Mental Health, University Health Network, Toronto, Ontario, Canada.

Mark Osten (M)

Peter Munk Cardiac Center, University Health Network, Toronto, Ontario, Canada.

Maral Ouzounian (M)

Peter Munk Cardiac Center, University Health Network, Toronto, Ontario, Canada.

Gerald Devins (G)

Center for Mental Health, University Health Network, Toronto, Ontario, Canada.

Amy Deckert (A)

Center for Mental Health, University Health Network, Toronto, Ontario, Canada.

Eric Horlick (E)

Peter Munk Cardiac Center, University Health Network, Toronto, Ontario, Canada.

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