Unnecessary antibiotic prescribing in a Canadian primary care setting: a descriptive analysis using routinely collected electronic medical record data.

Adolescent Adult Anti-Bacterial Agents Canada / epidemiology Child Child, Preschool Drug Prescriptions / statistics & numerical data Electronic Health Records Female Humans Inappropriate Prescribing / statistics & numerical data Male Middle Aged Practice Patterns, Physicians' Primary Health Care Young Adult

Journal

CMAJ open
ISSN: 2291-0026
Titre abrégé: CMAJ Open
Pays: Canada
ID NLM: 101620603

Informations de publication

Date de publication:
Historique:
entrez: 9 5 2020
pubmed: 10 5 2020
medline: 10 5 2020
Statut: epublish

Résumé

Unnecessary antibiotic use in the community in Canada is not well defined. Our objective was to quantify unnecessary antibiotic prescribing in a Canadian primary care setting. We performed a descriptive analysis in Ontario from April 2011 to March 2016 using the Electronic Medical Records Primary Care database linked to other health administrative data sets at ICES. We determined antibiotic prescribing rates (per 100 patient-physician encounters) for 23 common conditions and estimated rates of unnecessary prescribing using predefined expected prescribing rates, both stratified by condition and patient age group. The study included 341 physicians, 204 313 patients and 499 570 encounters. The rate of unnecessary antibiotic prescribing for included conditions was 15.4% overall and was 17.6% for those less than 2 years of age, 18.6% for those aged 2-18, 14.5% for those aged 19-64 and 13.0% for those aged 65 or more. The highest unnecessary prescribing rates were observed for acute bronchitis (52.6%), acute sinusitis (48.4%) and acute otitis media (39.3%). The common cold, acute bronchitis, acute sinusitis and miscellaneous nonbacterial infections were responsible for 80% of the unnecessary antibiotic prescriptions. Of all antibiotics prescribed, 12.0% were for conditions for which they are never indicated, and 12.3% for conditions for which they are rarely indicated. In children, 25% of antibiotics were for conditions for which they are never indicated (e.g., common cold). Antibiotics were prescribed unnecessarily for 15.4% of included encounters in a Canadian primary care setting. Almost one-quarter of antibiotics were prescribed for conditions for which they are rarely or never indicated. These findings should guide safe reductions in the use of antibiotics for the common cold, bronchitis and sinusitis.

Sections du résumé

BACKGROUND
Unnecessary antibiotic use in the community in Canada is not well defined. Our objective was to quantify unnecessary antibiotic prescribing in a Canadian primary care setting.
METHODS
We performed a descriptive analysis in Ontario from April 2011 to March 2016 using the Electronic Medical Records Primary Care database linked to other health administrative data sets at ICES. We determined antibiotic prescribing rates (per 100 patient-physician encounters) for 23 common conditions and estimated rates of unnecessary prescribing using predefined expected prescribing rates, both stratified by condition and patient age group.
RESULTS
The study included 341 physicians, 204 313 patients and 499 570 encounters. The rate of unnecessary antibiotic prescribing for included conditions was 15.4% overall and was 17.6% for those less than 2 years of age, 18.6% for those aged 2-18, 14.5% for those aged 19-64 and 13.0% for those aged 65 or more. The highest unnecessary prescribing rates were observed for acute bronchitis (52.6%), acute sinusitis (48.4%) and acute otitis media (39.3%). The common cold, acute bronchitis, acute sinusitis and miscellaneous nonbacterial infections were responsible for 80% of the unnecessary antibiotic prescriptions. Of all antibiotics prescribed, 12.0% were for conditions for which they are never indicated, and 12.3% for conditions for which they are rarely indicated. In children, 25% of antibiotics were for conditions for which they are never indicated (e.g., common cold).
INTERPRETATION
Antibiotics were prescribed unnecessarily for 15.4% of included encounters in a Canadian primary care setting. Almost one-quarter of antibiotics were prescribed for conditions for which they are rarely or never indicated. These findings should guide safe reductions in the use of antibiotics for the common cold, bronchitis and sinusitis.

Identifiants

DOI: 10.9778/cmajo.20190175 PMID: 32381687 PMC: PMC7207032
pubmed: 32381687
pii: 8/2/E360
doi: 10.9778/cmajo.20190175
pmc: PMC7207032
doi:

Substances chimiques

Anti-Bacterial Agents 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Pagination

E360-E369

Informations de copyright

Copyright 2020, Joule Inc. or its licensors.

Déclaration de conflit d'intérêts

Competing interests: None declared.

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Auteurs

Kevin L Schwartz (KL)

Public Health Ontario (Schwartz, Langford, Brown, Johnstone, Leung, Wu, Garber); ICES Central (Schwartz, Daneman, Chen, Brown, Candido); Unity Health Network (Langford), St. Joseph Health Centre; Sunnybrook Research Institute (Daneman); Ray D. Wolfe Department of Family Medicine (McIsaac), Sinai Health System; Departments of Family & Community Medicine (McIsaac, Tu) and Laboratory Medicine and Pathobiology (Johnstone), University of Toronto; North York General Hospital (Tu); Toronto Western Hospital Family Health Team (Tu), University Health Network; Toronto East Health Network (Leung), Michael Garron Hospital; Dalla Lana School of Public Health (Hwee), University of Toronto, Toronto, Ont.; Institute for Better Health (Hwee), Trillium Health Partners, Mississauga, Ont.; London Health Sciences Centre (Silverman), London, Ont.; Ottawa Hospital Research Institute (Garber); Department of Medicine (Garber), University of Ottawa, Ottawa, Ont. Kevin.schwartz@oahpp.ca.

Bradley J Langford (BJ)

Public Health Ontario (Schwartz, Langford, Brown, Johnstone, Leung, Wu, Garber); ICES Central (Schwartz, Daneman, Chen, Brown, Candido); Unity Health Network (Langford), St. Joseph Health Centre; Sunnybrook Research Institute (Daneman); Ray D. Wolfe Department of Family Medicine (McIsaac), Sinai Health System; Departments of Family & Community Medicine (McIsaac, Tu) and Laboratory Medicine and Pathobiology (Johnstone), University of Toronto; North York General Hospital (Tu); Toronto Western Hospital Family Health Team (Tu), University Health Network; Toronto East Health Network (Leung), Michael Garron Hospital; Dalla Lana School of Public Health (Hwee), University of Toronto, Toronto, Ont.; Institute for Better Health (Hwee), Trillium Health Partners, Mississauga, Ont.; London Health Sciences Centre (Silverman), London, Ont.; Ottawa Hospital Research Institute (Garber); Department of Medicine (Garber), University of Ottawa, Ottawa, Ont.

Nick Daneman (N)

Public Health Ontario (Schwartz, Langford, Brown, Johnstone, Leung, Wu, Garber); ICES Central (Schwartz, Daneman, Chen, Brown, Candido); Unity Health Network (Langford), St. Joseph Health Centre; Sunnybrook Research Institute (Daneman); Ray D. Wolfe Department of Family Medicine (McIsaac), Sinai Health System; Departments of Family & Community Medicine (McIsaac, Tu) and Laboratory Medicine and Pathobiology (Johnstone), University of Toronto; North York General Hospital (Tu); Toronto Western Hospital Family Health Team (Tu), University Health Network; Toronto East Health Network (Leung), Michael Garron Hospital; Dalla Lana School of Public Health (Hwee), University of Toronto, Toronto, Ont.; Institute for Better Health (Hwee), Trillium Health Partners, Mississauga, Ont.; London Health Sciences Centre (Silverman), London, Ont.; Ottawa Hospital Research Institute (Garber); Department of Medicine (Garber), University of Ottawa, Ottawa, Ont.

Branson Chen (B)

Public Health Ontario (Schwartz, Langford, Brown, Johnstone, Leung, Wu, Garber); ICES Central (Schwartz, Daneman, Chen, Brown, Candido); Unity Health Network (Langford), St. Joseph Health Centre; Sunnybrook Research Institute (Daneman); Ray D. Wolfe Department of Family Medicine (McIsaac), Sinai Health System; Departments of Family & Community Medicine (McIsaac, Tu) and Laboratory Medicine and Pathobiology (Johnstone), University of Toronto; North York General Hospital (Tu); Toronto Western Hospital Family Health Team (Tu), University Health Network; Toronto East Health Network (Leung), Michael Garron Hospital; Dalla Lana School of Public Health (Hwee), University of Toronto, Toronto, Ont.; Institute for Better Health (Hwee), Trillium Health Partners, Mississauga, Ont.; London Health Sciences Centre (Silverman), London, Ont.; Ottawa Hospital Research Institute (Garber); Department of Medicine (Garber), University of Ottawa, Ottawa, Ont.

Kevin A Brown (KA)

Public Health Ontario (Schwartz, Langford, Brown, Johnstone, Leung, Wu, Garber); ICES Central (Schwartz, Daneman, Chen, Brown, Candido); Unity Health Network (Langford), St. Joseph Health Centre; Sunnybrook Research Institute (Daneman); Ray D. Wolfe Department of Family Medicine (McIsaac), Sinai Health System; Departments of Family & Community Medicine (McIsaac, Tu) and Laboratory Medicine and Pathobiology (Johnstone), University of Toronto; North York General Hospital (Tu); Toronto Western Hospital Family Health Team (Tu), University Health Network; Toronto East Health Network (Leung), Michael Garron Hospital; Dalla Lana School of Public Health (Hwee), University of Toronto, Toronto, Ont.; Institute for Better Health (Hwee), Trillium Health Partners, Mississauga, Ont.; London Health Sciences Centre (Silverman), London, Ont.; Ottawa Hospital Research Institute (Garber); Department of Medicine (Garber), University of Ottawa, Ottawa, Ont.

Warren McIsaac (W)

Public Health Ontario (Schwartz, Langford, Brown, Johnstone, Leung, Wu, Garber); ICES Central (Schwartz, Daneman, Chen, Brown, Candido); Unity Health Network (Langford), St. Joseph Health Centre; Sunnybrook Research Institute (Daneman); Ray D. Wolfe Department of Family Medicine (McIsaac), Sinai Health System; Departments of Family & Community Medicine (McIsaac, Tu) and Laboratory Medicine and Pathobiology (Johnstone), University of Toronto; North York General Hospital (Tu); Toronto Western Hospital Family Health Team (Tu), University Health Network; Toronto East Health Network (Leung), Michael Garron Hospital; Dalla Lana School of Public Health (Hwee), University of Toronto, Toronto, Ont.; Institute for Better Health (Hwee), Trillium Health Partners, Mississauga, Ont.; London Health Sciences Centre (Silverman), London, Ont.; Ottawa Hospital Research Institute (Garber); Department of Medicine (Garber), University of Ottawa, Ottawa, Ont.

Karen Tu (K)

Public Health Ontario (Schwartz, Langford, Brown, Johnstone, Leung, Wu, Garber); ICES Central (Schwartz, Daneman, Chen, Brown, Candido); Unity Health Network (Langford), St. Joseph Health Centre; Sunnybrook Research Institute (Daneman); Ray D. Wolfe Department of Family Medicine (McIsaac), Sinai Health System; Departments of Family & Community Medicine (McIsaac, Tu) and Laboratory Medicine and Pathobiology (Johnstone), University of Toronto; North York General Hospital (Tu); Toronto Western Hospital Family Health Team (Tu), University Health Network; Toronto East Health Network (Leung), Michael Garron Hospital; Dalla Lana School of Public Health (Hwee), University of Toronto, Toronto, Ont.; Institute for Better Health (Hwee), Trillium Health Partners, Mississauga, Ont.; London Health Sciences Centre (Silverman), London, Ont.; Ottawa Hospital Research Institute (Garber); Department of Medicine (Garber), University of Ottawa, Ottawa, Ont.

Elisa Candido (E)

Public Health Ontario (Schwartz, Langford, Brown, Johnstone, Leung, Wu, Garber); ICES Central (Schwartz, Daneman, Chen, Brown, Candido); Unity Health Network (Langford), St. Joseph Health Centre; Sunnybrook Research Institute (Daneman); Ray D. Wolfe Department of Family Medicine (McIsaac), Sinai Health System; Departments of Family & Community Medicine (McIsaac, Tu) and Laboratory Medicine and Pathobiology (Johnstone), University of Toronto; North York General Hospital (Tu); Toronto Western Hospital Family Health Team (Tu), University Health Network; Toronto East Health Network (Leung), Michael Garron Hospital; Dalla Lana School of Public Health (Hwee), University of Toronto, Toronto, Ont.; Institute for Better Health (Hwee), Trillium Health Partners, Mississauga, Ont.; London Health Sciences Centre (Silverman), London, Ont.; Ottawa Hospital Research Institute (Garber); Department of Medicine (Garber), University of Ottawa, Ottawa, Ont.

Jennie Johnstone (J)

Public Health Ontario (Schwartz, Langford, Brown, Johnstone, Leung, Wu, Garber); ICES Central (Schwartz, Daneman, Chen, Brown, Candido); Unity Health Network (Langford), St. Joseph Health Centre; Sunnybrook Research Institute (Daneman); Ray D. Wolfe Department of Family Medicine (McIsaac), Sinai Health System; Departments of Family & Community Medicine (McIsaac, Tu) and Laboratory Medicine and Pathobiology (Johnstone), University of Toronto; North York General Hospital (Tu); Toronto Western Hospital Family Health Team (Tu), University Health Network; Toronto East Health Network (Leung), Michael Garron Hospital; Dalla Lana School of Public Health (Hwee), University of Toronto, Toronto, Ont.; Institute for Better Health (Hwee), Trillium Health Partners, Mississauga, Ont.; London Health Sciences Centre (Silverman), London, Ont.; Ottawa Hospital Research Institute (Garber); Department of Medicine (Garber), University of Ottawa, Ottawa, Ont.

Valerie Leung (V)

Public Health Ontario (Schwartz, Langford, Brown, Johnstone, Leung, Wu, Garber); ICES Central (Schwartz, Daneman, Chen, Brown, Candido); Unity Health Network (Langford), St. Joseph Health Centre; Sunnybrook Research Institute (Daneman); Ray D. Wolfe Department of Family Medicine (McIsaac), Sinai Health System; Departments of Family & Community Medicine (McIsaac, Tu) and Laboratory Medicine and Pathobiology (Johnstone), University of Toronto; North York General Hospital (Tu); Toronto Western Hospital Family Health Team (Tu), University Health Network; Toronto East Health Network (Leung), Michael Garron Hospital; Dalla Lana School of Public Health (Hwee), University of Toronto, Toronto, Ont.; Institute for Better Health (Hwee), Trillium Health Partners, Mississauga, Ont.; London Health Sciences Centre (Silverman), London, Ont.; Ottawa Hospital Research Institute (Garber); Department of Medicine (Garber), University of Ottawa, Ottawa, Ont.

Jeremiah Hwee (J)

Public Health Ontario (Schwartz, Langford, Brown, Johnstone, Leung, Wu, Garber); ICES Central (Schwartz, Daneman, Chen, Brown, Candido); Unity Health Network (Langford), St. Joseph Health Centre; Sunnybrook Research Institute (Daneman); Ray D. Wolfe Department of Family Medicine (McIsaac), Sinai Health System; Departments of Family & Community Medicine (McIsaac, Tu) and Laboratory Medicine and Pathobiology (Johnstone), University of Toronto; North York General Hospital (Tu); Toronto Western Hospital Family Health Team (Tu), University Health Network; Toronto East Health Network (Leung), Michael Garron Hospital; Dalla Lana School of Public Health (Hwee), University of Toronto, Toronto, Ont.; Institute for Better Health (Hwee), Trillium Health Partners, Mississauga, Ont.; London Health Sciences Centre (Silverman), London, Ont.; Ottawa Hospital Research Institute (Garber); Department of Medicine (Garber), University of Ottawa, Ottawa, Ont.

Michael Silverman (M)

Public Health Ontario (Schwartz, Langford, Brown, Johnstone, Leung, Wu, Garber); ICES Central (Schwartz, Daneman, Chen, Brown, Candido); Unity Health Network (Langford), St. Joseph Health Centre; Sunnybrook Research Institute (Daneman); Ray D. Wolfe Department of Family Medicine (McIsaac), Sinai Health System; Departments of Family & Community Medicine (McIsaac, Tu) and Laboratory Medicine and Pathobiology (Johnstone), University of Toronto; North York General Hospital (Tu); Toronto Western Hospital Family Health Team (Tu), University Health Network; Toronto East Health Network (Leung), Michael Garron Hospital; Dalla Lana School of Public Health (Hwee), University of Toronto, Toronto, Ont.; Institute for Better Health (Hwee), Trillium Health Partners, Mississauga, Ont.; London Health Sciences Centre (Silverman), London, Ont.; Ottawa Hospital Research Institute (Garber); Department of Medicine (Garber), University of Ottawa, Ottawa, Ont.

Julie H C Wu (JHC)

Public Health Ontario (Schwartz, Langford, Brown, Johnstone, Leung, Wu, Garber); ICES Central (Schwartz, Daneman, Chen, Brown, Candido); Unity Health Network (Langford), St. Joseph Health Centre; Sunnybrook Research Institute (Daneman); Ray D. Wolfe Department of Family Medicine (McIsaac), Sinai Health System; Departments of Family & Community Medicine (McIsaac, Tu) and Laboratory Medicine and Pathobiology (Johnstone), University of Toronto; North York General Hospital (Tu); Toronto Western Hospital Family Health Team (Tu), University Health Network; Toronto East Health Network (Leung), Michael Garron Hospital; Dalla Lana School of Public Health (Hwee), University of Toronto, Toronto, Ont.; Institute for Better Health (Hwee), Trillium Health Partners, Mississauga, Ont.; London Health Sciences Centre (Silverman), London, Ont.; Ottawa Hospital Research Institute (Garber); Department of Medicine (Garber), University of Ottawa, Ottawa, Ont.

Gary Garber (G)

Public Health Ontario (Schwartz, Langford, Brown, Johnstone, Leung, Wu, Garber); ICES Central (Schwartz, Daneman, Chen, Brown, Candido); Unity Health Network (Langford), St. Joseph Health Centre; Sunnybrook Research Institute (Daneman); Ray D. Wolfe Department of Family Medicine (McIsaac), Sinai Health System; Departments of Family & Community Medicine (McIsaac, Tu) and Laboratory Medicine and Pathobiology (Johnstone), University of Toronto; North York General Hospital (Tu); Toronto Western Hospital Family Health Team (Tu), University Health Network; Toronto East Health Network (Leung), Michael Garron Hospital; Dalla Lana School of Public Health (Hwee), University of Toronto, Toronto, Ont.; Institute for Better Health (Hwee), Trillium Health Partners, Mississauga, Ont.; London Health Sciences Centre (Silverman), London, Ont.; Ottawa Hospital Research Institute (Garber); Department of Medicine (Garber), University of Ottawa, Ottawa, Ont.

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Classifications MeSH

questionsmedicales.fr › Personnes › Tranches d'âge › Adolescent › Unnecessary antibiotic prescribing in a...
questionsmedicales.fr › Personnes › Tranches d'âge › Adulte › Unnecessary antibiotic prescribing in a...
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Utilisations thérapeutiques › Anti-infectieux › Antibactériens › Unnecessary antibiotic prescribing in a...
questionsmedicales.fr › Régions géographiques › Amériques › Amérique du Nord › Canada › Unnecessary antibiotic prescribing in a...
questionsmedicales.fr › Personnes › Tranches d'âge › Enfant › Unnecessary antibiotic prescribing in a...
questionsmedicales.fr › Personnes › Tranches d'âge › Enfant › Enfant d'âge préscolaire › Unnecessary antibiotic prescribing in a...
questionsmedicales.fr › Établissements, main d'oeuvre et services de soins de santé › Services de santé › Services pharmaceutiques › Ordonnances › Ordonnances médicamenteuses › Unnecessary antibiotic prescribing in a...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Collecte de données › Documents › Dossiers médicaux › Systèmes informatisés de dossiers médicaux › Dossiers médicaux électroniques › Unnecessary antibiotic prescribing in a...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Unnecessary antibiotic prescribing in a...
questionsmedicales.fr › Établissements, main d'oeuvre et services de soins de santé › Services de santé › Erreurs médicales › Erreurs de médication › Prescription inappropriée › Unnecessary antibiotic prescribing in a...
questionsmedicales.fr › Personnes › Tranches d'âge › Adulte › Adulte d'âge moyen › Unnecessary antibiotic prescribing in a...
questionsmedicales.fr › Qualité, accès, évaluation des soins de santé › Prestations des soins de santé › Types de pratiques des médecins › Unnecessary antibiotic prescribing in a...
questionsmedicales.fr › Administration des services de santé › Gestion des soins aux patients › Services de santé polyvalents › Soins de santé primaires › Unnecessary antibiotic prescribing in a...
questionsmedicales.fr › Personnes › Tranches d'âge › Adulte › Jeune adulte › Unnecessary antibiotic prescribing in a...