Death from cardiac glycoside "pong-pong" following use as weight-loss supplement purchased on Internet.


Journal

The American journal of emergency medicine
ISSN: 1532-8171
Titre abrégé: Am J Emerg Med
Pays: United States
ID NLM: 8309942

Informations de publication

Date de publication:
08 2020
Historique:
received: 12 03 2020
accepted: 17 04 2020
pubmed: 11 5 2020
medline: 25 8 2020
entrez: 11 5 2020
Statut: ppublish

Résumé

Cerbera odollam or "pong-pong" tree contains cardiac glycosides similar to digoxin, oleander and yellow oleander. Cerbera odollam is a common method of suicide in South East Asia and has also been used as a weight loss supplement. We present a case of a 33-year-old female presenting with lethargy, vomiting, bradycardia, severe hyperkalemia of 8.9 mEq/L, slow atrial fibrillation followed by cardiovascular collapse following the ingestion of "pong-pong", the kernel of Cerbera odollam, as a weight loss supplement. Despite the administration of a total of nine vials of digoxin-specific Fab the patient could not be resuscitated. Clinicians should be aware of natural cardiac glycosides being uses as weight-loss agents and consider acute cardiac glycoside poisoning in patients with hyperkalemia, abnormal cardiovascular signs, symptoms and abnormal ECG findings.

Identifiants

pubmed: 32387148
pii: S0735-6757(20)30289-8
doi: 10.1016/j.ajem.2020.04.063
pii:
doi:

Substances chimiques

Anti-Obesity Agents 0
Cardiac Glycosides 0

Types de publication

Case Reports Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1698.e5-1698.e6

Informations de copyright

Copyright © 2020 Elsevier Inc. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of competing interest The authors declare no conflicts of interest.

Auteurs

Sean Patrick Nordt (SP)

University of Southern California, Department of Emergency Medicine, Los Angeles, CA, United States of America; University of California, Irvine, Department of Emergency Medicine, Orange, CA, United States of America; Chapman University, School of Pharmacy, Irvine, CA, United States of America. Electronic address: spnordt@hotmail.com.

Matt Hendrickson (M)

Northridge Hospital Medical Center, Emergency Department, Northridge, CA, United States of America.

Kimberly Won (K)

Chapman University, School of Pharmacy, Irvine, CA, United States of America.

Matthew J Miller (MJ)

Department of Medical Examiner-Coroner, County of Los Angeles, Los Angeles, CA, United States of America.

Stuart P Swadron (SP)

University of Southern California, Department of Emergency Medicine, Los Angeles, CA, United States of America.

F Lee Cantrell (FL)

California Poison Control System, San Diego Division, San Diego, CA, United States of America.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female
Humans United States Aged Cross-Sectional Studies Medicare Part C
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH