Death from cardiac glycoside "pong-pong" following use as weight-loss supplement purchased on Internet.
Cardiac glycoside
Cerbera odollam
Poisoning
Pong-pong
Weight loss
Journal
The American journal of emergency medicine
ISSN: 1532-8171
Titre abrégé: Am J Emerg Med
Pays: United States
ID NLM: 8309942
Informations de publication
Date de publication:
08 2020
08 2020
Historique:
received:
12
03
2020
accepted:
17
04
2020
pubmed:
11
5
2020
medline:
25
8
2020
entrez:
11
5
2020
Statut:
ppublish
Résumé
Cerbera odollam or "pong-pong" tree contains cardiac glycosides similar to digoxin, oleander and yellow oleander. Cerbera odollam is a common method of suicide in South East Asia and has also been used as a weight loss supplement. We present a case of a 33-year-old female presenting with lethargy, vomiting, bradycardia, severe hyperkalemia of 8.9 mEq/L, slow atrial fibrillation followed by cardiovascular collapse following the ingestion of "pong-pong", the kernel of Cerbera odollam, as a weight loss supplement. Despite the administration of a total of nine vials of digoxin-specific Fab the patient could not be resuscitated. Clinicians should be aware of natural cardiac glycosides being uses as weight-loss agents and consider acute cardiac glycoside poisoning in patients with hyperkalemia, abnormal cardiovascular signs, symptoms and abnormal ECG findings.
Identifiants
pubmed: 32387148
pii: S0735-6757(20)30289-8
doi: 10.1016/j.ajem.2020.04.063
pii:
doi:
Substances chimiques
Anti-Obesity Agents
0
Cardiac Glycosides
0
Types de publication
Case Reports
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
1698.e5-1698.e6Informations de copyright
Copyright © 2020 Elsevier Inc. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of competing interest The authors declare no conflicts of interest.