Characterization of the Impact of Daclizumab Beta on Circulating Natural Killer Cells by Mass Cytometry.


Journal

Frontiers in immunology
ISSN: 1664-3224
Titre abrégé: Front Immunol
Pays: Switzerland
ID NLM: 101560960

Informations de publication

Date de publication:
2020
Historique:
received: 21 11 2019
accepted: 30 03 2020
entrez: 12 5 2020
pubmed: 12 5 2020
medline: 1 4 2021
Statut: epublish

Résumé

Daclizumab beta is a humanized monoclonal antibody that binds to CD25 and selectively inhibits high-affinity IL-2 receptor signaling. As a former treatment for relapsing forms of multiple sclerosis (RMS), daclizumab beta induces robust expansion of the CD56

Identifiants

pubmed: 32391016
doi: 10.3389/fimmu.2020.00714
pmc: PMC7194113
doi:

Substances chimiques

CD56 Antigen 0
Immunosuppressive Agents 0
NCAM1 protein, human 0
Receptors, Natural Killer Cell 0
Daclizumab CUJ2MVI71Y

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

714

Informations de copyright

Copyright © 2020 Ranganath, Simpson, Ferreira, Seiler, Vendrame, Zhao, Fontenot, Holmes and Blish.

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Auteurs

Thanmayi Ranganath (T)

Department of Medicine, Stanford University School of Medicine, Stanford, CA, United States.

Laura J Simpson (LJ)

Department of Medicine, Stanford University School of Medicine, Stanford, CA, United States.

Anne-Maud Ferreira (AM)

Department of Statistics, Stanford University, Stanford, CA, United States.

Christof Seiler (C)

Department of Statistics, Stanford University, Stanford, CA, United States.

Elena Vendrame (E)

Department of Medicine, Stanford University School of Medicine, Stanford, CA, United States.

Nancy Zhao (N)

Department of Medicine, Stanford University School of Medicine, Stanford, CA, United States.

Jason D Fontenot (JD)

Biogen, Cambridge, MA, United States.

Susan Holmes (S)

Department of Statistics, Stanford University, Stanford, CA, United States.

Catherine A Blish (CA)

Department of Medicine, Stanford University School of Medicine, Stanford, CA, United States.
Chan Zuckerberg Biohub, San Francisco, CA, United States.

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Classifications MeSH