Report on G4-Med, a Geant4 benchmarking system for medical physics applications developed by the Geant4 Medical Simulation Benchmarking Group.


Journal

Medical physics
ISSN: 2473-4209
Titre abrégé: Med Phys
Pays: United States
ID NLM: 0425746

Informations de publication

Date de publication:
Jan 2021
Historique:
received: 10 07 2019
revised: 26 04 2020
accepted: 30 04 2020
pubmed: 12 5 2020
medline: 1 5 2021
entrez: 12 5 2020
Statut: ppublish

Résumé

Geant4 is a Monte Carlo code extensively used in medical physics for a wide range of applications, such as dosimetry, micro- and nanodosimetry, imaging, radiation protection, and nuclear medicine. Geant4 is continuously evolving, so it is crucial to have a system that benchmarks this Monte Carlo code for medical physics against reference data and to perform regression testing. To respond to these needs, we developed G4-Med, a benchmarking and regression testing system of Geant4 for medical physics. G4-Med currently includes 18 tests. They range from the benchmarking of fundamental physics quantities to the testing of Monte Carlo simulation setups typical of medical physics applications. Both electromagnetic and hadronic physics processes and models within the prebuilt Geant4 physics lists are tested. The tests included in G4-Med are executed on the CERN computing infrastructure via the use of the geant-val web application, developed at CERN for Geant4 testing. The physical observables can be compared to reference data for benchmarking and to results of previous Geant4 versions for regression testing purposes. This paper describes the tests included in G4-Med and shows the results derived from the benchmarking of Geant4 10.5 against reference data. Our results indicate that the Geant4 electromagnetic physics constructor G4EmStandardPhysics_option4 gives a good agreement with the reference data for all the tests. The QGSP_BIC_HP physics list provided an overall adequate description of the physics involved in hadron therapy, including proton and carbon ion therapy. New tests should be included in the next stage of the project to extend the benchmarking to other physical quantities and application scenarios of interest for medical physics. The results presented and discussed in this paper will aid users in tailoring physics lists to their particular application.

Sections du résumé

BACKGROUND BACKGROUND
Geant4 is a Monte Carlo code extensively used in medical physics for a wide range of applications, such as dosimetry, micro- and nanodosimetry, imaging, radiation protection, and nuclear medicine. Geant4 is continuously evolving, so it is crucial to have a system that benchmarks this Monte Carlo code for medical physics against reference data and to perform regression testing.
AIMS OBJECTIVE
To respond to these needs, we developed G4-Med, a benchmarking and regression testing system of Geant4 for medical physics.
MATERIALS AND METHODS METHODS
G4-Med currently includes 18 tests. They range from the benchmarking of fundamental physics quantities to the testing of Monte Carlo simulation setups typical of medical physics applications. Both electromagnetic and hadronic physics processes and models within the prebuilt Geant4 physics lists are tested. The tests included in G4-Med are executed on the CERN computing infrastructure via the use of the geant-val web application, developed at CERN for Geant4 testing. The physical observables can be compared to reference data for benchmarking and to results of previous Geant4 versions for regression testing purposes.
RESULTS RESULTS
This paper describes the tests included in G4-Med and shows the results derived from the benchmarking of Geant4 10.5 against reference data.
DISCUSSION CONCLUSIONS
Our results indicate that the Geant4 electromagnetic physics constructor G4EmStandardPhysics_option4 gives a good agreement with the reference data for all the tests. The QGSP_BIC_HP physics list provided an overall adequate description of the physics involved in hadron therapy, including proton and carbon ion therapy. New tests should be included in the next stage of the project to extend the benchmarking to other physical quantities and application scenarios of interest for medical physics.
CONCLUSION CONCLUSIONS
The results presented and discussed in this paper will aid users in tailoring physics lists to their particular application.

Identifiants

pubmed: 32392626
doi: 10.1002/mp.14226
pmc: PMC8054528
mid: NIHMS1690578
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

19-56

Subventions

Organisme : NCI NIH HHS
ID : U24 CA215123
Pays : United States
Organisme : Spanish Ministry of Economy and Competitiveness
ID : FPA2016-77689-C2-1-R
Organisme : Susan G Komen Foundation
ID : IIR13262248
Organisme : Australian Government Research Training Program Scholarship
ID : 000
Organisme : NIH HHS
ID : U24CA215123
Pays : United States
Organisme : Australian Research Council
ID : DP170102423
Organisme : Australian Research Council
ID : DP170100967
Organisme : European Space Agency
ID : 4000126645/19/NL/BW

Informations de copyright

© 2020 American Association of Physicists in Medicine.

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Auteurs

P Arce (P)

CIEMAT, Madrid, Spain.

D Bolst (D)

Centre For Medical Radiation Physics, University of Wollongong, Wollongong, Australia.

M-C Bordage (MC)

CRCT (INSERM and Paul Sabatier University), Toulouse, France.

J M C Brown (JMC)

Department of Radiation Science and Technology, Delft University of Technology, Delft, The Netherlands.

P Cirrone (P)

INFN LNS, Catania, Italy.

M A Cortés-Giraldo (MA)

Universidad de Sevilla, Sevilla, Spain.

D Cutajar (D)

Centre For Medical Radiation Physics, University of Wollongong, Wollongong, Australia.

G Cuttone (G)

INFN LNS, Catania, Italy.

L Desorgher (L)

Institute of Radiation Physics (IRA), Lausanne University Hospital, Lausanne, Switzerland.

P Dondero (P)

SWHARD srl, Genova, Italy.

A Dotti (A)

SLAC National Accelerator Laboratory, Stanford, CA, USA.

B Faddegon (B)

University of California, San Francisco, CA, USA.

C Fedon (C)

Radboud University Medical Center, Nijmegen, The Netherlands.

S Guatelli (S)

Centre For Medical Radiation Physics, University of Wollongong, Wollongong, Australia.

S Incerti (S)

Université de Bordeaux, CNRS/IN2P3, UMR5797, Centre d'Études Nucléaires de Bordeaux Gradignan, Gradignan, France.

V Ivanchenko (V)

Tomsk State University, Tomsk, Russian Federation.
CERN, Geneva, Switzerland.

D Konstantinov (D)

NRC "Kurchatov Institute" - IHEP, Protvino, Russian Federation.

I Kyriakou (I)

Medical Physics Laboratory, University of Ioannina, Ioannina, Greece.

G Latyshev (G)

NRC "Kurchatov Institute" - IHEP, Protvino, Russian Federation.

A Le (A)

Centre For Medical Radiation Physics, University of Wollongong, Wollongong, Australia.

C Mancini-Terracciano (C)

Physics Dep., University of Rome "Sapienza" and INFN, Sec. of Rome, Rome, Italy.

M Maire (M)

LAPP, IN2P3, Annecy, France.

A Mantero (A)

SWHARD srl, Genova, Italy.

M Novak (M)

CERN, Geneva, Switzerland.

C Omachi (C)

Nagoya Proton Therapy Center, Nagoya, Japan.

L Pandola (L)

INFN LNS, Catania, Italy.

A Perales (A)

Medical Physics Department of Clínica Universidad de Navarra, Pamplona, Spain.

Y Perrot (Y)

IRSN, Fontenay-aux-Roses, France.

G Petringa (G)

INFN LNS, Catania, Italy.

J M Quesada (JM)

Universidad de Sevilla, Sevilla, Spain.

J Ramos-Méndez (J)

University of California, San Francisco, CA, USA.

F Romano (F)

INFN Catania Section, Catania, Italy.
Medical Physics Department, National Physical Laboratory, Teddington, UK.

A B Rosenfeld (AB)

Centre For Medical Radiation Physics, University of Wollongong, Wollongong, Australia.

L G Sarmiento (LG)

Lund University, Lund, Sweden.

D Sakata (D)

Centre For Medical Radiation Physics, University of Wollongong, Wollongong, Australia.

T Sasaki (T)

KEK, Tsukuba, Japan.

I Sechopoulos (I)

Radboud University Medical Center, Nijmegen, The Netherlands.
Dutch Expert Center for Screening (LRCB), Nijmegen, The Netherlands.

E C Simpson (EC)

Department of Nuclear Physics, Research School of Physics, Australian National University, Canberra, Australia.

T Toshito (T)

Nagoya Proton Therapy Center, Nagoya, Japan.

D H Wright (DH)

SLAC National Accelerator Laboratory, Stanford, CA, USA.

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