Impact of Intensive Lifestyle Treatment (Diet Plus Exercise) on Endothelial and Vascular Function, Arterial Stiffness and Blood Pressure in Stage 1 Hypertension: Results of the HINTreat Randomized Controlled Trial.


Journal

Nutrients
ISSN: 2072-6643
Titre abrégé: Nutrients
Pays: Switzerland
ID NLM: 101521595

Informations de publication

Date de publication:
07 05 2020
Historique:
received: 20 04 2020
revised: 02 05 2020
accepted: 04 05 2020
entrez: 13 5 2020
pubmed: 13 5 2020
medline: 17 2 2021
Statut: epublish

Résumé

Lifestyle modification is an important component of essential hypertension (EH) therapy. The aim of the Hypertension Intensive Nutrition Treatment (HINTreat) parallel, randomized controlled trial was to examine the effect of a 6-month intensive lifestyle treatment (ILT) (diet plus exercise with monthly visits) compared to the usual care. A total of 76 adults with stage 1 EH were randomized (38 in each group). Dietary analysis, anthropometry, physical activity, biochemical and urine profile, blood pressure (BP), asymmetric dimethylarginine (ADMA), central hemodynamics, β-stiffness index and carotid intima media-thickness were evaluated. The dietary inflammatory index (DII) was calculated for each participant from the intake of 29 nutrients/food components. At the end of the trial, participants in the ILT group reduced their 24h urinary Na excretion (

Identifiants

pubmed: 32392715
pii: nu12051326
doi: 10.3390/nu12051326
pmc: PMC7284619
pii:
doi:

Substances chimiques

N,N-dimethylarginine 63CV1GEK3Y
Arginine 94ZLA3W45F

Types de publication

Journal Article Randomized Controlled Trial

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : Supporting Research and Academic Practices of the 3rd Internal Medicine Department
ID : 91770
Pays : International

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Auteurs

Anastasios Vamvakis (A)

Third Department of Internal Medicine, Papageorgiou Hospital, Aristotle University of Thessaloniki, GR56403 Thessaloniki, Greece.

Eugenia Gkaliagkousi (E)

Third Department of Internal Medicine, Papageorgiou Hospital, Aristotle University of Thessaloniki, GR56403 Thessaloniki, Greece.

Antonios Lazaridis (A)

Third Department of Internal Medicine, Papageorgiou Hospital, Aristotle University of Thessaloniki, GR56403 Thessaloniki, Greece.

Maria G Grammatikopoulou (MG)

Department of Nutritional Sciences & Dietetics, Faculty of Health Sciences, International Hellenic University, Alexander Campus, Sindos, PO Box 141, GR57400 Thessaloniki, Greece.

Areti Triantafyllou (A)

Third Department of Internal Medicine, Papageorgiou Hospital, Aristotle University of Thessaloniki, GR56403 Thessaloniki, Greece.

Barbara Nikolaidou (B)

Third Department of Internal Medicine, Papageorgiou Hospital, Aristotle University of Thessaloniki, GR56403 Thessaloniki, Greece.

Nikolaos Koletsos (N)

Third Department of Internal Medicine, Papageorgiou Hospital, Aristotle University of Thessaloniki, GR56403 Thessaloniki, Greece.

Panagiota Anyfanti (P)

Third Department of Internal Medicine, Papageorgiou Hospital, Aristotle University of Thessaloniki, GR56403 Thessaloniki, Greece.

Christos Tzimos (C)

Northern Greece Statistics Directorate, Hellenic Statistical Authority, 218 Delfon Str, GR54646 Thessaloniki, Greece.

Pantelis Zebekakis (P)

Division of Endocrinology and Metabolism and Diabetes Center, First Department of Internal Medicine, Medical School, AHEPA University Hospital, Aristotle University of Thessaloniki, GR54621 Thessaloniki, Greece.

Stella Douma (S)

Third Department of Internal Medicine, Papageorgiou Hospital, Aristotle University of Thessaloniki, GR56403 Thessaloniki, Greece.

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Classifications MeSH