A novel HPLC method developed and validated for the detection and quantification of atorvastatin, fluvastatin, pitavastatin and pravastatin during transdermal delivery studies.
Administration, Cutaneous
Atorvastatin
/ analysis
Chromatography, High Pressure Liquid
/ methods
Drug Delivery Systems
Excipients
/ chemistry
Fluvastatin
/ analysis
Hydroxymethylglutaryl-CoA Reductase Inhibitors
/ administration & dosage
Limit of Detection
Pravastatin
/ analysis
Quinolines
/ analysis
Journal
Die Pharmazie
ISSN: 0031-7144
Titre abrégé: Pharmazie
Pays: Germany
ID NLM: 9800766
Informations de publication
Date de publication:
01 05 2020
01 05 2020
Historique:
entrez:
13
5
2020
pubmed:
13
5
2020
medline:
23
4
2021
Statut:
ppublish
Résumé
An HPLC method was developed and validated to quantify and identify several statins (atorvastatin, fluvastatin, pitavastatin and pravastatin) that were used during transdermal drug delivery. The method proved to be most effective with a Restek Ultra C
Identifiants
pubmed: 32393420
doi: 10.1691/ph.2020.0007
doi:
Substances chimiques
Excipients
0
Hydroxymethylglutaryl-CoA Reductase Inhibitors
0
Quinolines
0
Fluvastatin
4L066368AS
Atorvastatin
A0JWA85V8F
Pravastatin
KXO2KT9N0G
pitavastatin
M5681Q5F9P
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Validation Study
Langues
eng
Sous-ensembles de citation
IM