Bax inhibitor-1 deficiency leads to obesity by increasing Ca
Animals
Calcium
/ metabolism
Disease Models, Animal
Disease Susceptibility
Eating
Fatty Liver
/ etiology
Gene Expression Regulation
Genotype
Glucose
/ metabolism
Insulin Secretion
Liver
/ metabolism
Membrane Proteins
/ deficiency
Mice
Mice, Knockout
Obesity
/ etiology
RNA Splicing
Thermogenesis
/ genetics
X-Box Binding Protein 1
/ genetics
Bax inhibitor-1
Hepatic Steatosis
Insulin secretion
Obesity
TMBIM6
Journal
Journal of molecular medicine (Berlin, Germany)
ISSN: 1432-1440
Titre abrégé: J Mol Med (Berl)
Pays: Germany
ID NLM: 9504370
Informations de publication
Date de publication:
06 2020
06 2020
Historique:
received:
28
10
2019
accepted:
21
04
2020
revised:
14
04
2020
pubmed:
13
5
2020
medline:
8
6
2021
entrez:
13
5
2020
Statut:
ppublish
Résumé
Transmembrane BAX inhibitor motif containing 6 (TMBIM6), also known as Bax inhibitor-1, is an evolutionarily conserved protein involved in endoplasmic reticulum (ER) function. TMBIM6 is an ER Ca
Identifiants
pubmed: 32394396
doi: 10.1007/s00109-020-01914-x
pii: 10.1007/s00109-020-01914-x
pmc: PMC7297831
doi:
Substances chimiques
Membrane Proteins
0
Tmbim6 protein, mouse
0
X-Box Binding Protein 1
0
Xbp1 protein, mouse
0
Glucose
IY9XDZ35W2
Calcium
SY7Q814VUP
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
849-862Références
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