Robot-assisted intracorporeal orthotopic bladder substitution after radical cystectomy: perioperative morbidity and oncological outcomes - a single-institution experience.


Journal

BJU international
ISSN: 1464-410X
Titre abrégé: BJU Int
Pays: England
ID NLM: 100886721

Informations de publication

Date de publication:
10 2020
Historique:
pubmed: 14 5 2020
medline: 21 1 2021
entrez: 14 5 2020
Statut: ppublish

Résumé

To report a single-institution experience with totally intracorporeal neobladder urinary diversion (UD) after robot-assisted laparoscopic radical cystectomy (RARC). A total of 158 patients underwent totally intracorporeal neobladder UD after RARC between 2003 and 2016. Patient demographics, intraoperative and pathological data, 30- and 90-day perioperative mortality and complications were recorded. Complications were classified according to the modified Clavien-Dindo classification. The 5-year overall (OS) and cancer-specific survival (CSS) rates were estimated by Kaplan-Meier plots. Most of the patients were male (84%) and had clinical T Stage ≤2 (87%). The mean operation time was 359 (SD ±98) min, with a median (range) estimated blood loss of 300 (50-2200) mL. Most of the men (86%) received a nerve-sparing procedure and 38% of the females an organ-sparing approach. A lymph node dissection was performed in 156 (99%) patients, with a median (range) yield of 23 (7-48) nodes. Conversion to open surgery occurred in five patients (3%). We recorded negative margins in 156 patients (99%). The median (range) follow-up was 34 (1-170) months, with 30- and 90-day mortality rates of 0%. Clavien-Dindo Grade III-IV complications occurred in 29 of 158 (18%) patients at 30-days and in eight of 158 (5%) between 30-90 days, resulting into a 90-day overall high-grade complication rate of 23%. The unadjusted estimated 5-years recurrence-free survival, CSS and OS rates were 70%, 72%, and 71%, respectively. In our present series the complication and oncological results were similar to open RC series, suggesting that RARC followed by totally intracorporeal neobladder UD is a safe and feasible alternative.

Identifiants

pubmed: 32403199
doi: 10.1111/bju.15112
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

464-471

Subventions

Organisme : Krebsliga Schweiz
ID : BIL KLS-4558-08-2018
Pays : International

Informations de copyright

© 2020 The Authors BJU International published by John Wiley & Sons Ltd on behalf of BJU International.

Références

Zamboni S, Soria F, Mathieu R et al. Differences in trends in the use of robot-assisted and open radical cystectomy and changes over time in peri-operative outcomes among selected centres in North America and Europe: an international multicentre collaboration. BJU Int 2019; 124: 656-64
Hussein AA, May PR, Jing Z et al. Outcomes of intracorporeal urinary diversion after robot-assisted radical cystectomy: results from the International Robotic Cystectomy Consortium. J Urol 2018; 199: 1302-11
Hosseini A, Adding C, Nilsson A, Jonsson MN, Wiklund NP. Robotic cystectomy: surgical technique. BJU Int 2011; 108: 962-8
Collins JW, Adding C, Hosseini A et al. Introducing an enhanced recovery programme to an established totally intracorporeal robot-assisted radical cystectomy service. Scand J Urol 2016; 50: 39-46
Dindo D, Demartines N, Clavien PA. Classification of surgical complications: a new proposal with evaluation in a cohort of 6336 patients and results of a survey. Ann Surg 2004; 240: 205-13
Hosseini A, Ebbing J, Collins J. Clinical outcomes of robot-assisted radical cystectomy and continent urinary diversion. Scand J Urol 2019; 53: 81-8
Sathianathen NJ, Kalapara A, Frydenberg M et al. Robotic assisted radical cystectomy vs open radical cystectomy: systematic review and meta-analysis. J Urol 2019; 201: 715-20
Parekh DJ, Reis IM, Castle EP et al. Robot-assisted radical cystectomy versus open radical cystectomy in patients with bladder cancer (RAZOR): an open-label, randomised, phase 3, non-inferiority trial. Lancet 2018; 391: 2525-36
Bochner BH, Dalbagni G, Sjoberg DD et al. Comparing open radical cystectomy and robot-assisted laparoscopic radical cystectomy: a randomized clinical trial. Eur Urol 2015; 67: 1042-50
Gandaglia G, Karl A, Novara G et al. Perioperative and oncologic outcomes of robot-assisted vs. open radical cystectomy in bladder cancer patients: a comparison of two high-volume referral centers. Eur J Surg Oncol 2016; 42: 1736-43
Bertolo R, Agudelo J, Garisto J, Armanyous S, Fergany A, Kaouk J. Perioperative outcomes and complications after robotic radical cystectomy with intracorporeal or extracorporeal ileal conduit urinary diversion: head-to-head comparison from a single-institutional prospective study. Urology 2019; 129: 98-105
Lenfant L, Verhoest G, Campi R et al. Perioperative outcomes and complications of intracorporeal vs extracorporeal urinary diversion after robot-assisted radical cystectomy for bladder cancer: a real-life, multi-institutional French study. World J Urol 2018; 36: 1711-8
Tan TW, Nair R, Saad S, Thurairaja R, Khan MS. Safe transition from extracorporeal to intracorporeal urinary diversion following robot-assisted cystectomy: a recipe for reducing operative time, blood loss and complication rates. World J Urol 2019; 37: 367-72
Tan WS, Lamb BW, Kelly JD. Evolution of the neobladder: a critical review of open and intracorporeal neobladder reconstruction techniques. Scand J Urol 2016; 50: 95-103
Chan KG, Collins JW, Wiklund NP. Robot-assisted radical cystectomy: extracorporeal vs intracorporeal urinary diversion. J Urol 2015; 193: 1467-9
Zhang JJH, Ericson KJ, Thomas LJ et al. Large Single-institution comparison of perioperative outcomes and complications in open radical cystectomy, intracorporeal robot-assisted radical cystectomy, and robotic extracorporeal approach. J Urol 2020; 203: 512-21.
Asimakopoulos AD, Campagna A, Gakis G et al. Nerve sparing, robot-assisted radical cystectomy with intracorporeal bladder substitution in the male. J Urol 2016; 196: 1549-57
Desai MM, Gill IS, de Castro Abreu AL et al. Robotic intracorporeal orthotopic neobladder during radical cystectomy in 132 patients. J Urol 2014; 192: 1734-40
Goh AC, Gill IS, Lee DJ et al. Robotic intracorporeal orthotopic ileal neobladder: replicating open surgical principles. Eur Urol 2012; 62: 891-901
Gok B, Atmaca AF, Canda AE et al. Robotic radical cystectomy with intracorporeal studer pouch formation for bladder cancer: experience in ninety-eight cases. J Endourol 2019; 33: 375-82
Koie T, Ohyama C, Makiyama K et al. Utility of robot-assisted radical cystectomy with intracorporeal urinary diversion for muscle-invasive bladder cancer. Int J Urol 2019; 26: 334-40
Koie T, Ohyama C, Yoneyama T et al. Robotic cross-folded U-configuration intracorporeal ileal neobladder for muscle-invasive bladder cancer: Initial experience and functional outcomes. Int J Med Robot 2018; 14: e1955
Simone G, Papalia R, Misuraca L et al. Robotic intracorporeal padua ileal bladder: surgical technique, perioperative, oncologic and functional outcomes. Eur Urol 2018; 73: 934-40
Simone G, Tuderti G, Misuraca L et al. Perioperative and mid-term oncologic outcomes of robotic assisted radical cystectomy with totally intracorporeal neobladder: results of a propensity score matched comparison with open cohort from a single-centre series. Eur J Surg Oncol 2018; 44: 1432-8
Tan WS, Lamb BW, Tan MY et al. In-depth critical analysis of complications following robot-assisted radical cystectomy with intracorporeal urinary diversion. Eur Urol Focus 2017; 3: 273-9
Tan WS, Sridhar A, Goldstraw M et al. Robot-assisted intracorporeal pyramid neobladder. BJU Int 2015; 116: 771-9
Tyritzis SI, Hosseini A, Collins J et al. Oncologic, functional, and complications outcomes of robot-assisted radical cystectomy with totally intracorporeal neobladder diversion. Eur Urol 2013; 64: 734-41
Schwentner C, Sim A, Balbay MD et al. Robot-assisted radical cystectomy and intracorporeal neobladder formation: on the way to a standardized procedure. World J Surg Oncol 2015; 13: 3
Hautmann RE, de Petriconi RC, Volkmer BG. Lessons learned from 1,000 neobladders: the 90-day complication rate. J Urol 2010; 184: 990-4; quiz 1235.
Collins JW, Patel H, Adding C et al. enhanced recovery after robot-assisted radical cystectomy: EAU robotic urology section scientific working group consensus view. Eur Urol 2016; 70: 649-60
Novotny V, Hakenberg OW, Wiessner D et al. Perioperative complications of radical cystectomy in a contemporary series. Eur Urol 2007; 51: 397-401
Nieuwenhuijzen JA, de Vries RR, Bex A et al. Urinary diversions after cystectomy: the association of clinical factors, complications and functional results of four different diversions. Eur Urol 2008; 53: 834-42
Nguyen DP, Al Hussein Al Awamlh B, Wu X et al. Recurrence patterns after open and robot-assisted radical cystectomy for bladder cancer. Eur Urol 2015; 68: 399-405
Yuh B, Wilson T, Bochner B et al. Systematic review and cumulative analysis of oncologic and functional outcomes after robot-assisted radical cystectomy. Eur Urol 2015; 67: 402-22
Raza SJ, Wilson T, Peabody JO et al. Long-term oncologic outcomes following robot-assisted radical cystectomy: results from the International Robotic Cystectomy Consortium. Eur Urol 2015; 68: 721-8
Gschwend JE, Heck MM, Lehmann J et al. Extended versus limited lymph node dissection in bladder cancer patients undergoing radical cystectomy: survival results from a prospective, randomized trial. Eur Urol 2019; 75: 604-11
Stein JP, Lieskovsky G, Cote R et al. Radical cystectomy in the treatment of invasive bladder cancer: long-term results in 1,054 patients. J Clin Oncol. 2001; 19: 666-75
Hussein AA, Elsayed AS, Aldhaam NA et al. Comparison of long-term oncologic outcomes among historical open and minimally invasive retrospective studies. J Urol 2019; 269: 887-94
Collins JW, Wiklund NP. Totally intracorporeal robot-assisted radical cystectomy: optimizing total outcomes. BJU Int 2014; 114: 326-33
Pridgeon S, Bishop CV, Adshead J. Lower limb compartment syndrome as a complication of robot-assisted radical prostatectomy: the UK experience. BJU Int 2013; 112: 485-8
Quddus A, Lawlor M, Siddiqui A, Holmes P, Plant GT. Using diffusion-weighted magnetic resonance imaging to confirm a diagnosis of posterior ischaemic optic neuropathy: two case reports and literature review. Neuroophthalmology 2015; 39: 161-5
Stevens WR, Glazer PA, Kelley SD, Lietman TM, Bradford DS. Ophthalmic complications after spinal surgery. Spine 1997; 22: 1319-24
Williams EL, Hart WM Jr, Tempelhoff R. Postoperative ischemic optic neuropathy. Anesth Analg 1995; 80: 1018-29

Auteurs

Abolfazl Hosseini (A)

Department of Molecular Medicine and Surgery, Section of Urology, Karolinska Institutet, Stockholm, Sweden.

Ashkan Mortezavi (A)

Department of Molecular Medicine and Surgery, Section of Urology, Karolinska Institutet, Stockholm, Sweden.
Department of Urology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.

Siri Sjöberg (S)

Department of Molecular Medicine and Surgery, Section of Urology, Karolinska Institutet, Stockholm, Sweden.

Oscar Laurin (O)

Department of Molecular Medicine and Surgery, Section of Urology, Karolinska Institutet, Stockholm, Sweden.

Christofer Adding (C)

Department of Molecular Medicine and Surgery, Section of Urology, Karolinska Institutet, Stockholm, Sweden.

Justin Collins (J)

Department of Molecular Medicine and Surgery, Section of Urology, Karolinska Institutet, Stockholm, Sweden.
Department of Urology, UCLH, London, UK.

Peter N Wiklund (PN)

Department of Molecular Medicine and Surgery, Section of Urology, Karolinska Institutet, Stockholm, Sweden.
Department of Urology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female
Humans United States Aged Cross-Sectional Studies Medicare Part C
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH