What is the impact of continuous neuromonitoring on the incidence of injury to the recurrent laryngeal nerve during total thyroidectomy?


Journal

Surgery
ISSN: 1532-7361
Titre abrégé: Surgery
Pays: United States
ID NLM: 0417347

Informations de publication

Date de publication:
01 2021
Historique:
received: 03 02 2020
revised: 17 03 2020
accepted: 24 03 2020
pubmed: 16 5 2020
medline: 27 4 2021
entrez: 16 5 2020
Statut: ppublish

Résumé

Continuous intraoperative neuromonitoring may facilitate reversal of intraoperative injurious operative maneuvers in comparison with intermittent intraoperative neuromonitoring. The aim of this study was to evaluate the impact of the routine use of continuous intraoperative neuromonitoring on intraoperative injuries to the recurrent laryngeal nerve. This study was a prospective case series with retrospective analysis of consecutive patients undergoing total thyroidectomy from August 2013 to August 2019. During this period, intermittent intraoperative neuromonitoring (before Mar 2016) and continuous intraoperative neuromonitoring (after Mar 2016) were used in all patients. We reviewed the outcomes of 603 patients (466 female patients) comprising 236 who underwent intermittent intraoperative neuromonitoring and 367 who underwent continuous intraoperative neuromonitoring. Intraoperative adverse electromyography events (>50% decrease in amplitude between VN1 and VN2) were observed in 87 patients (14.5%) and were less frequent in the continuous intraoperative neuromonitoring group (10.6 vs 20.3%, P = .001). Intraoperative loss of signal (electromyography events with VN2 ≤100μV) were observed in 35 patients (5.8%) without any difference between the 2 groups of patients (5.2 vs 6.8%, P = .415). Postoperative recurrent laryngeal nerve palsies were observed in 36 patients (5.9%) without any difference between the 2 groups of patients (4.9 vs 7.6%, P = .168). The routine use of continuous intraoperative neuromonitoring improves the rate of intraoperative adverse electromyography events but does not impact significantly the rates of loss of signal and recurrent laryngeal nerve palsy.

Sections du résumé

BACKGROUND
Continuous intraoperative neuromonitoring may facilitate reversal of intraoperative injurious operative maneuvers in comparison with intermittent intraoperative neuromonitoring. The aim of this study was to evaluate the impact of the routine use of continuous intraoperative neuromonitoring on intraoperative injuries to the recurrent laryngeal nerve.
METHOD
This study was a prospective case series with retrospective analysis of consecutive patients undergoing total thyroidectomy from August 2013 to August 2019. During this period, intermittent intraoperative neuromonitoring (before Mar 2016) and continuous intraoperative neuromonitoring (after Mar 2016) were used in all patients.
RESULTS
We reviewed the outcomes of 603 patients (466 female patients) comprising 236 who underwent intermittent intraoperative neuromonitoring and 367 who underwent continuous intraoperative neuromonitoring. Intraoperative adverse electromyography events (>50% decrease in amplitude between VN1 and VN2) were observed in 87 patients (14.5%) and were less frequent in the continuous intraoperative neuromonitoring group (10.6 vs 20.3%, P = .001). Intraoperative loss of signal (electromyography events with VN2 ≤100μV) were observed in 35 patients (5.8%) without any difference between the 2 groups of patients (5.2 vs 6.8%, P = .415). Postoperative recurrent laryngeal nerve palsies were observed in 36 patients (5.9%) without any difference between the 2 groups of patients (4.9 vs 7.6%, P = .168).
CONCLUSION
The routine use of continuous intraoperative neuromonitoring improves the rate of intraoperative adverse electromyography events but does not impact significantly the rates of loss of signal and recurrent laryngeal nerve palsy.

Identifiants

pubmed: 32409167
pii: S0039-6060(20)30173-2
doi: 10.1016/j.surg.2020.03.029
pii:
doi:

Types de publication

Journal Article Observational Study

Langues

eng

Sous-ensembles de citation

IM

Pagination

63-69

Informations de copyright

Copyright © 2020 Elsevier Inc. All rights reserved.

Auteurs

Florence Bihain (F)

Université de Lorraine, Département de Chirurgie Viscérale, Métabolique et Cancérologique (CVMC), CHRU Nancy, Hopital de Brabois (7(ème) étage), Vandoeuvre-les-Nancy, France.

Claire Nomine-Criqui (C)

Université de Lorraine, Département de Chirurgie Viscérale, Métabolique et Cancérologique (CVMC), CHRU Nancy, Hopital de Brabois (7(ème) étage), Vandoeuvre-les-Nancy, France.

Léa Demarquet (L)

Université de Lorraine, Département d'Endocrinologie, Diabétologie, Nutrition (EDN), CHRU Nancy, Hopital de Brabois, Vandoeuvre-les-Nancy, France.

Claire Blanchard (C)

Université de Nantes, Clinique de Chirurgie Cancérologique, Digestive et Endocrinienne (CCDE), Institut des Maladies de l'Appareil Digestif (IMAD), Université de Nantes, Quai de Tourville, France.

Patrice Gallet (P)

Université de Lorraine, Département d'Oto-Rhino-Laryngologie, CHRU Nancy, Hopital de Brabois, Vandoeuvre-les-Nancy, France.

Phi-Linh Nguyen (PL)

Université de Lorraine, CHRU Nancy, Département d'évaluation médicale Medical, Plateforme d'aide à la recherche clinique (PARC), France.

Eric Mirallie (E)

Université de Nantes, Clinique de Chirurgie Cancérologique, Digestive et Endocrinienne (CCDE), Institut des Maladies de l'Appareil Digestif (IMAD), Université de Nantes, Quai de Tourville, France.

Laurent Brunaud (L)

Université de Lorraine, Département de Chirurgie Viscérale, Métabolique et Cancérologique (CVMC), CHRU Nancy, Hopital de Brabois (7(ème) étage), Vandoeuvre-les-Nancy, France; Université de Lorraine, INSERM U1256, « Nutrition, Genetics, Environmental Risks », Faculté de Médecine, Vandoeuvre-les-Nancy, France. Electronic address: l.brunaud@chru-nancy.fr.

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