Preoperative carbohydrates: what is new?
Biomarkers
/ blood
Blood Glucose
/ metabolism
Diet, Carbohydrate Loading
/ methods
Dietary Carbohydrates
/ administration & dosage
Humans
Hyperglycemia
/ prevention & control
Insulin Resistance
Observational Studies as Topic
Postoperative Complications
/ prevention & control
Preoperative Care
/ methods
Prospective Studies
Randomized Controlled Trials as Topic
Retrospective Studies
Journal
Current opinion in clinical nutrition and metabolic care
ISSN: 1473-6519
Titre abrégé: Curr Opin Clin Nutr Metab Care
Pays: England
ID NLM: 9804399
Informations de publication
Date de publication:
07 2020
07 2020
Historique:
pubmed:
16
5
2020
medline:
7
8
2021
entrez:
16
5
2020
Statut:
ppublish
Résumé
The aim of this review is to give an overview of recently published articles covering preoperative carbohydrate loading in surgical patients. Between January 1, 2017, and December 31, 2019, 26 publications addressing the effect of carbohydrate load were retrieved through a systematic search. Seventeen were randomized clinical trials, three prospective observational studies and six retrospective series with case-control comparison. Most of the studies were underpowered, addressed surrogate endpoints, and variability among dose and timing of carbohydrate (CHO) treatment was high. The most recent literature endorses preoperative carbohydrate loading up to 2 h before operations as a safe treatment. The new evidence confirm that this strategy is effective in reducing perioperative insulin resistance and the proportion of hyperglycemia episodes, and improving patient well-being and comfort but without affecting surgery-related morbidity. Further properly designed randomized clinical trials, addressing more clinically relevant endpoints such as length of hospitalization and morbidity rate, are warrant.
Identifiants
pubmed: 32412978
doi: 10.1097/MCO.0000000000000661
pii: 00075197-202007000-00008
doi:
Substances chimiques
Biomarkers
0
Blood Glucose
0
Dietary Carbohydrates
0
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
262-270Références
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