Interaction of amphiphilic coumarin with DPPC/DPPS lipid bilayer: effects of concentration and alkyl tail length.
Journal
Physical chemistry chemical physics : PCCP
ISSN: 1463-9084
Titre abrégé: Phys Chem Chem Phys
Pays: England
ID NLM: 100888160
Informations de publication
Date de publication:
21 Jul 2020
21 Jul 2020
Historique:
pubmed:
19
5
2020
medline:
15
12
2020
entrez:
19
5
2020
Statut:
ppublish
Résumé
In this work, interactions between amphiphilic amino methyl coumarin and dipalmitoyl-sn-glycero-3-phosphocholine/dipalmitoyl-sn-glycero-3-phosphoserine (DPPC/DPPS) lipid bilayer were investigated. A combination of experimental techniques (zeta potential, fluorescence spectroscopy, and differential scanning calorimetry) along with molecular dynamics simulations was employed to examine the influence of alkyl tail length and concentration of the amphiphilic coumarin on the lipid bilayer. Alkyl tails comprising 5(C
Substances chimiques
Coumarins
0
Lipid Bilayers
0
Phosphatidylserines
0
Surface-Active Agents
0
1,2-Dipalmitoylphosphatidylcholine
2644-64-6
dipalmitoylphosphatidylserine
3036-82-6
coumarin
A4VZ22K1WT
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM