Early Outcomes of Outpatient Management of Kidney Transplant Recipients with Coronavirus Disease 2019.
COVID-19
Cohort Studies
Dyspnea
Nonparametric
Outpatients
SARS-CoV2
Statistics
coronavirus
creatinine
hospitalization
kidney transplantation
severe acute respiratory syndrome coronavirus 2
Journal
Clinical journal of the American Society of Nephrology : CJASN
ISSN: 1555-905X
Titre abrégé: Clin J Am Soc Nephrol
Pays: United States
ID NLM: 101271570
Informations de publication
Date de publication:
07 08 2020
07 08 2020
Historique:
received:
15
04
2020
accepted:
07
05
2020
pubmed:
20
5
2020
medline:
26
8
2020
entrez:
20
5
2020
Statut:
ppublish
Résumé
Outcomes of kidney transplant recipients diagnosed with coronavirus disease 2019 as outpatients have not been described. We obtained clinical data for 41 consecutive outpatient kidney transplant recipients with known or suspected coronavirus disease 2019. Chi-squared and Wilcoxon rank sum tests were used to compare characteristics of patients who required hospitalization versus those who did not. Of 41 patients, 22 (54%) had confirmed coronavirus disease 2019, and 19 (46%) were suspected cases. Patients most commonly reported fever (80%), cough (56%), and dyspnea (39%). At the end of follow-up, 13 patients (32%) required hospitalization a median of 8 days (range, 1-16) after symptom onset, and 23 (56%) had outpatient symptom resolution a median of 12 days (4-23) after onset. Patients who required hospitalization were more likely to have reported dyspnea (77% versus 21%, In an early cohort of outpatient kidney transplant recipients with known or suspected coronavirus disease 2019, many had symptomatic resolution without requiring hospitalization.
Sections du résumé
BACKGROUND AND OBJECTIVES
Outcomes of kidney transplant recipients diagnosed with coronavirus disease 2019 as outpatients have not been described.
DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS
We obtained clinical data for 41 consecutive outpatient kidney transplant recipients with known or suspected coronavirus disease 2019. Chi-squared and Wilcoxon rank sum tests were used to compare characteristics of patients who required hospitalization versus those who did not.
RESULTS
Of 41 patients, 22 (54%) had confirmed coronavirus disease 2019, and 19 (46%) were suspected cases. Patients most commonly reported fever (80%), cough (56%), and dyspnea (39%). At the end of follow-up, 13 patients (32%) required hospitalization a median of 8 days (range, 1-16) after symptom onset, and 23 (56%) had outpatient symptom resolution a median of 12 days (4-23) after onset. Patients who required hospitalization were more likely to have reported dyspnea (77% versus 21%,
CONCLUSIONS
In an early cohort of outpatient kidney transplant recipients with known or suspected coronavirus disease 2019, many had symptomatic resolution without requiring hospitalization.
Identifiants
pubmed: 32423908
pii: 01277230-202008000-00016
doi: 10.2215/CJN.05170420
pmc: PMC7409755
doi:
Substances chimiques
Immunosuppressive Agents
0
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Langues
eng
Sous-ensembles de citation
IM
Pagination
1174-1178Subventions
Organisme : NCATS NIH HHS
ID : KL2 TR001874
Pays : United States
Organisme : NIDDK NIH HHS
ID : U01 DK116066
Pays : United States
Organisme : NIMHD NIH HHS
ID : R01 MD014161
Pays : United States
Commentaires et corrections
Type : CommentIn
Type : CommentIn
Informations de copyright
Copyright © 2020 by the American Society of Nephrology.
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