Molecular and Functional Characterization of
Elovl4
Gilthead seabream
Senegalese sole
functional characterization
neural tissue development
tissue expression
very long-chain polyunsaturated fatty acid
Journal
International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791
Informations de publication
Date de publication:
15 May 2020
15 May 2020
Historique:
received:
20
04
2020
revised:
11
05
2020
accepted:
12
05
2020
entrez:
21
5
2020
pubmed:
21
5
2020
medline:
11
2
2021
Statut:
epublish
Résumé
Very long-chain fatty acids (VLC-FA) play critical roles in neural tissues during the early development of vertebrates. However, studies on VLC-FA in fish are scarce. The biosynthesis of VLC-FA is mediated by elongation of very long-chain fatty acid 4 (Elovl4) proteins and, consequently, the complement and activity of these enzymes determines the capacity that a given species has for satisfying its physiological demands, in particular for the correct development of neurophysiological functions. The present study aimed to characterize and localize the expression of
Identifiants
pubmed: 32429178
pii: ijms21103514
doi: 10.3390/ijms21103514
pmc: PMC7278935
pii:
doi:
Substances chimiques
Fatty Acids
0
Membrane Proteins
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : Ministerio de Economía y Competitividad, Gobierno de España
ID : AGL 2013-40986-R
Organisme : Generalitat Valenciana
ID : PROMETEO II / 2014/085
Organisme : Ministerio de Economía y Competitividad, Gobierno de España
ID : AGL2011-23502
Organisme : FP7 People: Marie-Curie Actions
ID : FP7-PEOPLE-2010-RG, Project No. 274184
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