Histological and Histomorphometrical Evaluation of a New Implant Macrogeometry. A Sheep Study.
dental implants
healing chamber
osseointegration
osteogenic matrix
Journal
International journal of environmental research and public health
ISSN: 1660-4601
Titre abrégé: Int J Environ Res Public Health
Pays: Switzerland
ID NLM: 101238455
Informations de publication
Date de publication:
16 05 2020
16 05 2020
Historique:
received:
08
04
2020
revised:
12
05
2020
accepted:
13
05
2020
entrez:
21
5
2020
pubmed:
21
5
2020
medline:
6
11
2020
Statut:
epublish
Résumé
Decompression or healing chambers between the threads have been proposed to improve and accelerate the osseointegration process of dental implants. The aim of the present work was to test, in an in vivo sheep study, if healing chambers between the threads could produce a better osseointegration process. Thirty titanium implants (15 conventional design (control) and 15 implants with healing chambers (test)) were inserted in a random fashion in the tibia of 3 sheep. The animals were euthanized after 30 days of healing, and the retrieved specimens treated to obtain thin ground sections. Histological observations showed that the quantity of newly formed bone growing in an apical direction was lower in the control group (1095 µm) when compared to the Test group (1658 µm). This difference was statistically significant. Moreover, a layer of osteogenic matrix was present around the portion of implants immersed in the marrow spaces. This osteogenic tissue was thicker in the test group. In conclusion, the present study confirmed the very good results in implants with healing chambers that presented a higher percentage of new bone formation.
Identifiants
pubmed: 32429405
pii: ijerph17103477
doi: 10.3390/ijerph17103477
pmc: PMC7277453
pii:
doi:
Substances chimiques
Titanium
D1JT611TNE
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Références
Clin Oral Implants Res. 2004 Apr;15(2):249-57
pubmed: 15008938
J Biomed Mater Res B Appl Biomater. 2009 Nov;91(2):975-9
pubmed: 19582841
PLoS One. 2018 Aug 29;13(8):e0202957
pubmed: 30157237
Clin Implant Dent Relat Res. 2015 Jun;17(3):453-60
pubmed: 24020511
Odontology. 2014 Jul;102(2):259-66
pubmed: 23783569
Biomed Pharmacother. 2004 Nov;58(9):487-93
pubmed: 15511604
Int J Prosthodont. 1998 Sep-Oct;11(5):391-401
pubmed: 9922731
Clin Implant Dent Relat Res. 2014 Aug;16(4):572-81
pubmed: 23305450
J Biomed Mater Res B Appl Biomater. 2016 Aug;104(6):1091-7
pubmed: 26034012
Int J Oral Maxillofac Implants. 2013 May-Jun;28(3):694-700
pubmed: 23748299
J Long Term Eff Med Implants. 2010;20(4):335-42
pubmed: 21488826
Biomaterials. 1997 Apr;18(7):577-9
pubmed: 9105598
Clin Implant Dent Relat Res. 2010 Sep;12(3):202-8
pubmed: 19438947
Int J Oral Maxillofac Implants. 2011 Jan-Feb;26(1):75-82
pubmed: 21365041
J Dent Res. 2004 Jul;83(7):529-33
pubmed: 15218041
J Funct Biomater. 2019 Oct 25;10(4):
pubmed: 31731451
Int J Oral Maxillofac Implants. 2016 Nov 11;32(3):585–592
pubmed: 27835707
Biomed Res Int. 2017;2017:1970680
pubmed: 28293628
Mater Sci Eng C Mater Biol Appl. 2017 May 1;74:334-346
pubmed: 28254302
J Clin Med. 2019 May 31;8(6):
pubmed: 31159286
Int J Oral Maxillofac Surg. 2014 Oct;43(10):1269-75
pubmed: 24794761
J Biomed Mater Res B Appl Biomater. 2015 Aug;103(6):1328-32
pubmed: 25367155
J Bone Joint Surg Br. 1993 Mar;75(2):270-8
pubmed: 8444949
Clin Oral Implants Res. 2010 Jun;21(6):577-83
pubmed: 20105196
Clin Oral Implants Res. 2015 Nov;26(11):1256-60
pubmed: 24995491
Arch Biochem Biophys. 2014 Nov 1;561:99-108
pubmed: 25010447
J Biomed Mater Res B Appl Biomater. 2009 Jul;90(1):396-403
pubmed: 19107801
Adv Exp Med Biol. 2015;881:111-28
pubmed: 26545747
Clin Oral Implants Res. 2003 Feb;14(1):35-42
pubmed: 12562363
Clin Oral Implants Res. 2004 Aug;15(4):381-92
pubmed: 15248872
Adv Exp Med Biol. 2015;881:v-vii
pubmed: 26925474
Implant Dent. 2016 Oct;25(5):650-5
pubmed: 27540838