Immunomodulatory Effects of Vitamin D in Thyroid Diseases.

Humans Immunologic Factors / immunology Immunomodulation / immunology Thyroid Diseases / immunology Thyroiditis, Autoimmune / immunology Vitamin D / immunology Vitamin D Deficiency / immunology
immune system thyroid autoimmunity thyroid cancer vitamin D

Journal

Nutrients
ISSN: 2072-6643
Titre abrégé: Nutrients
Pays: Switzerland
ID NLM: 101521595

Informations de publication

Date de publication:
16 May 2020
Historique:
received: 19 04 2020
revised: 12 05 2020
accepted: 14 05 2020
entrez: 21 5 2020
pubmed: 21 5 2020
medline: 12 2 2021
Statut: epublish

Résumé

Vitamin D is a secosteroid with a pleiotropic role in multiple physiological processes. Besides the well-known activity on bone homeostasis, recent studies suggested a peculiar role of vitamin D in different non-skeletal pathways, including a key role in the modulation of immune responses. Recent evidences demonstrated that vitamin D acts on innate and adaptative immunity and seems to exert an immunomodulating action on autoimmune diseases and cancers. Several studies demonstrated a relationship between vitamin D deficiency, autoimmune thyroid disorders, and thyroid cancer. This review aims to summarize the evidences on the immunomodulatory effect of vitamin D on thyroid diseases.

Identifiants

DOI: 10.3390/nu12051444 PMID: 32429416 PMC: PMC7284826
pubmed: 32429416
pii: nu12051444
doi: 10.3390/nu12051444
pmc: PMC7284826
pii:
doi:

Substances chimiques

Immunologic Factors 0
Vitamin D 1406-16-2

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

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Auteurs

Chiara Mele (C)

Department of Translational Medicine, University of Piemonte Orientale UPO, 28100 Novara, Italy.
Division of General Medicine, S. Giuseppe Hospital, I.R.C.C.S. Istituto Auxologico Italiano, 28824 Verbania, Italy.

Marina Caputo (M)

Department of Health Sciences, University of Piemonte Orientale UPO, 28100 Novara, Italy.
Division of Endocrinology, University Hospital "Maggiore della Carità", 28100 Novara, Italy.

Alessandro Bisceglia (A)

Division of Endocrinology, Diabetology and Metabolism, Department of Medical Sciences, University of Turin, 10126 Turin, Italy.

Maria Teresa Samà (MT)

Division of Endocrinology, University Hospital "Maggiore della Carità", 28100 Novara, Italy.

Marco Zavattaro (M)

Division of Endocrinology, University Hospital "Maggiore della Carità", 28100 Novara, Italy.
Division of Endocrinology, Diabetology and Metabolism, Department of Medical Sciences, University of Turin, 10126 Turin, Italy.

Gianluca Aimaretti (G)

Department of Translational Medicine, University of Piemonte Orientale UPO, 28100 Novara, Italy.
Division of Endocrinology, University Hospital "Maggiore della Carità", 28100 Novara, Italy.

Loredana Pagano (L)

Division of Endocrinology, Diabetology and Metabolism, Department of Medical Sciences, University of Turin, 10126 Turin, Italy.

Flavia Prodam (F)

Department of Health Sciences, University of Piemonte Orientale UPO, 28100 Novara, Italy.
Division of Endocrinology, University Hospital "Maggiore della Carità", 28100 Novara, Italy.
ORCID: 0000-0001-9660-5335

Paolo Marzullo (P)

Department of Translational Medicine, University of Piemonte Orientale UPO, 28100 Novara, Italy.
Division of General Medicine, S. Giuseppe Hospital, I.R.C.C.S. Istituto Auxologico Italiano, 28824 Verbania, Italy.
ORCID: 0000-0003-3215-5747

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Immunomodulatory Effects of Vitamin D in...
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Effets physiologiques des médicaments › Facteurs immunologiques › Immunomodulatory Effects of Vitamin D in...
questionsmedicales.fr › Phénomènes du système immunitaire › Immunomodulation › Immunomodulatory Effects of Vitamin D in...
questionsmedicales.fr › Maladies endocriniennes › Maladies de la thyroïde › Immunomodulatory Effects of Vitamin D in...
questionsmedicales.fr › Maladies du système immunitaire › Maladies auto-immunes › Thyroïdite auto-immune › Immunomodulatory Effects of Vitamin D in...
questionsmedicales.fr › Composés polycycliques › Composés à cycles fusionnés › Stéroïdes › Sécostéroïdes › Vitamine D › Immunomodulatory Effects of Vitamin D in...
questionsmedicales.fr › Maladies métaboliques et nutritionnelles › Troubles nutritionnels › Malnutrition › Maladies de carence › Avitaminoses › Carence en vitamine D › Immunomodulatory Effects of Vitamin D in...